Results 51 to 60 of about 35,836 (258)
, 2015 Bar diagram showing fold change expression of FGF-2, FGFR-2 and FGFR-3 by Real Time. A, PCR in OSMF, LKP, OSCC and healthy controls. B, Frequency of FGF-2 malignant transformation rate in PMOLs.
Vikram Bhatia (406012) +6 more
core +1 more source
Association of FGF-2, FGFR-2 and FGFR-3 with clinico-pathological features in OSCC.
, 2015 Association of FGF-2, FGFR-2 and FGFR-3 with clinico-pathological features in OSCC.
Vikram Bhatia (406012) +6 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Relation of FGF-2, FGFR-2 and FGFR-3 expression with clinico-pathological parameters in PMOLs.
, 2015 Relation of FGF-2, FGFR-2 and FGFR-3 expression with clinico-pathological parameters in PMOLs.
Vikram Bhatia (406012) +6 more
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Mechanisms of FGFR-mediated carcinogenesis
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012 In this review, the evidence for a role of fibroblast growth factor receptor (FGFR) mediated signalling in carcinogenesis are considered and relevant underlying mechanisms highlighted. FGF signalling mediated by FGFR follows a classic receptor tyrosine kinase signalling pathway and its deregulation at various points of its cascade could result in ...
Ahmad, Imran +2 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang +4 more
wiley +1 more source
Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Targeting FGFR Signaling in Cancer [PDF]
Clinical Cancer Research, 2015 Abstract The fibroblast growth factor signaling pathway (FGFR signaling) is an evolutionary conserved signaling cascade that regulates several basic biologic processes, including tissue development, angiogenesis, and tissue regeneration. Substantial evidence indicates that aberrant FGFR signaling is involved in the pathogenesis of cancer.
Mehdi, Touat +4 more
openaire +2 more sources