Results 71 to 80 of about 32,832 (202)

Fibroblast Growth Factor Receptor, a Novel Receptor for Vegetative Insecticidal Protein Vip3Aa

Toxins, 2018
Vegetative insecticidal proteins (Vips), which are secreted by some Bacillus thuringiensis strains during vegetative growth, exhibit high virulence to many pests.
Kun Jiang, Xiaoyue Hou, Lu Han, Tongtong Tan, Zhanglei Cao, Jun Cai   +5 more
doaj   +1 more source

Clinical advances and challenges in targeting FGF/FGFR signaling in lung cancer

Molecular Cancer
Fibroblast growth factors (FGFs) and their receptors regulate numerous cellular processes, such as metabolism and signal transduction, but can also drive tumorigenesis.
Mei Peng, Jun Deng, Xiangping Li
doaj   +1 more source

FGFR families: biological functions and therapeutic interventions in tumors

MedComm, 2023
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and autophosphorylates, thereby activating several key downstream pathways that play an ...
Qing Liu, Jiyu Huang, Weiwei Yan, Zhen Liu, Shu Liu, Weiyi Fang   +5 more
doaj   +1 more source

Lineage-specific biomarkers predict response to FGFR inhibition

, 2012
In this issue of Cancer Discovery, Guagnano and colleagues use a large and diverse annotated collection of cancer cell lines, the Cancer Cell Line Encyclopedia, to correlate whole-genome expression and genomic alteration datasets with cell line ...
Pollock, Pamela M., Loch, David
core   +1 more source

The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking [PDF]

, 2009
Neural cell adhesion molecule (NCAM) associates with fibroblast growth factor (FGF) receptor-1 (FGFR1). However, the biological significance of this interaction remains largely elusive.
Vladimir Berezin, Gerhard Christofori, Christofori, Gerhard, Francavilla, Chiara; id_orcid, Paola Cattaneo, Cattaneo, Paola, Ugo Cavallaro, Cavallaro, Ugo, de Marco, Ario, Francavilla, Chiara, Ami, Diletta, Berezin, Vladimir, Ario de Marco, Chiara Francavilla, Bock, Elisabeth, Elisabeth Bock, Diletta Ami   +16 more
core   +1 more source

FGFR-TACC gene fusions in human glioma

, 2016
International audienceChromosomal translocations joining in-frame members of the fibroblast growth factor receptor–transforming acidic coiled-coil gene families (the FGFR-TACC gene fusions) were first discovered in human glioblastoma multiforme (GBM) and
Marc Sanson, Sanson, Marc, Lasorella, Anna, Iavarone, Antonio, Antonio Iavarone, Anna Lasorella   +5 more
core   +1 more source

Association of FGF-2, FGFR-2 and FGFR-3 with clinico-pathological features in OSCC.

, 2015
Association of FGF-2, FGFR-2 and FGFR-3 with clinico-pathological features in OSCC.
Vikram Bhatia (406012), Seema Nayak (813016), Annu Makker (813017), Saumya Chandra (813018), Sandeep Kumar (145759), Madhu Mati Goel (473426), S. P. Agarwal (813019)   +6 more
core   +1 more source

Relation of FGF-2, FGFR-2 and FGFR-3 expression with clinico-pathological parameters in PMOLs.

, 2015
Relation of FGF-2, FGFR-2 and FGFR-3 expression with clinico-pathological parameters in PMOLs.
Vikram Bhatia (406012), Seema Nayak (813016), Annu Makker (813017), Saumya Chandra (813018), Sandeep Kumar (145759), Madhu Mati Goel (473426), S. P. Agarwal (813019)   +6 more
core   +1 more source

Inhibition of FGFR Signaling by Targeting FGF/FGFR Extracellular Interactions: Towards the Comprehension of the Molecular Mechanism through NMR Approaches

, 2022
NMR-based approaches play a pivotal role in providing insight into molecular recognition mechanisms, affording the required atomic-level description and enabling the identification of promising inhibitors of protein–protein interactions.
Pagano, Katiuscia, Henriette Molinari, Laura Ragona, Taraboletti, Giulia, Ragona, Laura, Longhi, Elisa, Elisa Longhi, Giulia Taraboletti, Katiuscia Pagano, Molinari, Henriette   +9 more
core   +1 more source

Immunohistochemical staining of FGFR-2 (A-C).

, 2015
A, FGFR-2 positivity in transformed cases of Leukoplakia with dysplasia X 200. B, FGFR-2 positivity in transformed case of OSMF in fibrosis area X 100. C, FGFR-2 positivity in OSCC X 100.
Vikram Bhatia (406012), Seema Nayak (813016), Annu Makker (813017), Saumya Chandra (813018), Sandeep Kumar (145759), Madhu Mati Goel (473426), S. P. Agarwal (813019)   +6 more
core   +1 more source