Results 111 to 120 of about 14,040 (225)

Fibrations of Simplicial Sets [PDF]

open access: yesApplied Categorical Structures, 2009
There are infinitely many variants of the notion of Kan fibration that, together with suitable choices of cofibrations and the usual notion of weak equivalence of simplicial sets, satisfy Quillen's axioms for a homotopy model category. The combinatorics underlying these fibrations is purely finitary and seems interesting both for its own sake and for ...
openaire   +3 more sources

Statins, fibrates, and venous thromboembolism: a meta-analysis.

open access: yes, 2010
Aims The aim is to make a systematic review of the literature to assess the effect of lipid-lowering drugs on venous thromboembolism (VTE) occurrence. Methods and results MEDLINE and EMBASE databases were searched to identify studies that evaluated the
VENCO, ACHILLE   +16 more
core   +1 more source

The PROMINENT trial: swan song of the fibrates

open access: yes, 2023
Post hoc analyses of previous fibrate trials have suggested that individuals with type 2 diabetes mellitus with high triglyceride levels and low HDL-cholesterol levels benefit from fibrate therapy even when the overall trial results were neutral. However
Martens, Fabrice M.A.C.   +2 more
core  

Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP

open access: yesJournal of Cardiovascular Development and Disease, 2018
We previously reported how the loss of CHIP expression (Carboxyl terminus of Hsc70-Interacting Protein) during pressure overload resulted in robust cardiac dysfunction, which was accompanied by a failure to maintain ATP levels in the face of increased ...
Saranya Ravi   +9 more
doaj   +1 more source

On A∗-fibrations

open access: yesJournal of Pure and Applied Algebra, 2000
AbstractIn this paper we investigate minimal sufficient fibre conditions for a finitely generated flat algebra over a noetherian integral domain to be locally A∗ or at least an A∗-fibration. We also describe the structure of finitely generated locally A∗-algebras.
Bhatwadekar, S.M., Dutta, Amartya K.
openaire   +1 more source

MOESM6 of Statins and/or fibrates for diabetic retinopathy: a systematic review and meta-analysis

open access: yes, 2019
Additional file 6. Summary of findings table (fibrates compared to placebo for diabetic retinopathy)
Vânia Mozetic (7842722)   +3 more
core   +1 more source

LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia

open access: yesJournal of Lipid Research, 2012
ApoC-III is a proatherogenic protein associated with elevated triglycerides; its deficiency is associated with reduced atherosclerosis. Mixed dyslipidemia, characterized by elevated triglyceride and apoC-III levels and low HDL cholesterol level, with or ...
Ariel Brautbar   +5 more
doaj   +1 more source

Equivalence of shape fibrations and approximate fibrations

open access: yesTopology and its Applications, 1997
In this paper we give a description of approximate fibrations of arbitrary topological spaces using relations. Our method is to use relations with smaller and smaller images of points. This does not require any extensive knowledge of relations. The main result is that this improved version of the original concept of an approximate fibration of Coram ...
openaire   +1 more source

Fibrates for Primary Biliary Cholangitis: What’s All the Hype?

open access: yes, 2017
Ursodeoxycholic acid is the first-line therapy for primary biliary cholangitis. However, a subset of patients fail to show biochemical response. For these patients, adjuvant therapies are warranted. Obeticholic acid was conditionally approved as a second-
Cynthia Levy, Levy, Cynthia
core   +1 more source

Treatment with fibrates is associated with higher LAL activity in dyslipidemic patients [PDF]

open access: yes, 2019
Lysosomal acid lipase (LAL) is responsible for the hydrolysis of cholesteryl esters (CE) and triglycerides (TG) within the lysosomes; generated cholesterol and free fatty acids (FFA) are released in the cytosol where they can regulate their own synthesis
Gomaraschi, Monica   +8 more
core   +1 more source

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