Results 101 to 110 of about 14,279 (236)

Management of dyslipidemias with fibrates, alone and in combination with statins: role of delayed-release fenofibric acid

open access: yes, 2010
Elisavet Moutzouri, Anastazia Kei, Moses S Elisaf, Haralampos J MilionisDepartment of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, GreeceAbstract: Cardiovascular disease (CVD) represents the leading cause of mortality ...
Moses S Elisaf   +3 more
core  

Fibrates and estimated glomerular filtration rate: observations from an outpatient clinic setting and clinical implications.

open access: yes, 2012
BACKGROUND Previous studies have demonstrated that fibrates have an effect on creatinine concentrations. The pattern of change with fibrates in estimated glomerular filtration rate (eGFR), widely used in clinical practice, has not been previously ...
Raju, Jessie   +4 more
core   +1 more source

Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI

open access: yesJournal of Lipid Research, 2007
Treatment of atherosclerotic disease often focuses on reducing plasma LDL-cholesterol or increasing plasma HDL-cholesterol. We examined in vitro the effects on HDL receptor [scavenger receptor class B type I (SR-BI)] activity of three classes of clinical
Thomas J.F. Nieland   +6 more
doaj   +1 more source

Effects of esaxerenone add‐on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin–angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, reduces albuminuria; however, its effects on oxidative stress remain unclear.
Makoto Ohara   +9 more
wiley   +1 more source

The Pleiotropic Effects of Lipid-Modifying Interventions: Exploring Traditional and Emerging Hypolipidemic Therapies

open access: yesMetabolites
Atherosclerotic cardiovascular disease poses a significant global health issue, with dyslipidemia standing out as a major risk factor. In recent decades, lipid-lowering therapies have evolved significantly, with statins emerging as the cornerstone ...
Dimitris Kounatidis   +10 more
doaj   +1 more source

On A∗-fibrations

open access: yesJournal of Pure and Applied Algebra, 2000
AbstractIn this paper we investigate minimal sufficient fibre conditions for a finitely generated flat algebra over a noetherian integral domain to be locally A∗ or at least an A∗-fibration. We also describe the structure of finitely generated locally A∗-algebras.
Bhatwadekar, S.M., Dutta, Amartya K.
openaire   +1 more source

Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai   +5 more
wiley   +1 more source

Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-κ B activation [PDF]

open access: yes, 2002
Elsevier , Hirano, Y; Hirano, F; Fujii, H; Makino, I, EUROPEAN JOURNAL OF PHARMACOLOGY, 448(1), 2002, 19-26. authorFibrates, hypolipidemic agents, are reported to be effective in treatment of primary biliary cirrhosis. However, the mechanism involved in
Makino, I   +5 more
core   +1 more source

Fibrations of Simplicial Sets [PDF]

open access: yesApplied Categorical Structures, 2009
There are infinitely many variants of the notion of Kan fibration that, together with suitable choices of cofibrations and the usual notion of weak equivalence of simplicial sets, satisfy Quillen's axioms for a homotopy model category. The combinatorics underlying these fibrations is purely finitary and seems interesting both for its own sake and for ...
openaire   +4 more sources

Evaluating the Impact on Adult Caregivers of Family‐Based Treatment for Childhood Obesity

open access: yesObesity Science &Practice, Volume 12, Issue 5, October 2026.
ABSTRACT Background Weight management in children involves family lifestyle changes and relies on caregivers of children to implement these changes at home. Little is known about the effects of family‐based lifestyle intervention programs for children on caregivers themselves when not specifically targeted by the intervention.
Paola Luca   +7 more
wiley   +1 more source

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