Results 101 to 110 of about 14,825 (199)
Fibrates, glitazones, and peroxisome proliferator-activated receptors.
, 2010 International audienceSeveral decades ago, fibrates were approved for the treatment of dyslipidemia, whereas thiazolidinediones were screened in animal models to improve glucose homeostasis and were subsequently developed for the treatment of type 2 ...
Staels, Bart, Lalloyer, Fanny
core +1 more source
Current Issues in Pharmacy and Medical Sciences, 2012 A theoretical study on fibrate-type drugs in gas phase is presented. All stable conformations of fibric acid (as common and active moiety of these drugs) were identified and optimized at B3LYP/6-31+g(d) level.
Łukasz Komsta +2 more
doaj
JGH OpenObjective Peroxisome proliferator‐activated receptor (PPAR) agonists are agents used for patients with primary biliary cholangitis (PBC) who do not respond to conventional agents like ursodeoxycholic acid (UDCA).
Maadeha H. Zaidi +17 more
doaj +1 more source
Атеросклероз, 2016 This article is devoted to discussion about main aspects of current use of non-statin hypolipidemic drugs according last international guidelines (including fibrates, nicotinic acid, resins, polyunsaturated fatty acids, ezetimibe, PCSK9-inhibitors).
A. E. Bagriy +6 more
doaj
Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates
Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular ...
Abhinav Sharma +5 more
core +1 more source
Hyperlipidemia and gut microbiota: the role of prebiotics, probiotics, statins and fibrates
Сибирский научный медицинский журналAim of the study was to characterize the intestinal microbiota and its metabolites in hyperlipidemia and analyze the associations between the intestinal microbiota and some biological (prebiotics and probiotics) and lipid-lowering (statins, fibrates ...
I. N. Grigor’eva +2 more
doaj +1 more source
Рациональная фармакотерапия в кардиологииAim. To evaluate the prevalence, clinical features, and effectiveness of various lipid-lowering therapy (LLT) regimens in patients with extreme hypertriglyceridemia (EHTG).Material and methods.
A. V. Tyurina +4 more
doaj +1 more source
Pharmacokinetic interactions between statins and fibrates
, 2005 Concomitant use of a fibrate and a statin may offer a therapeutic advantage to patients with dyslipidemia, especially in patients whose low-density lipoprotein cholesterol is controlled by statins but whose high-density lipoprotein cholesterol or ...
S. Bellosta, A. Corsini, M. H. Davidson
core +1 more source
Coronary effect of fibrates on proteins and enzymes which hydrolyze triacylglycerols [PDF]
, 2016 Clofibric acid derivatives called fibrates, are quite commonly used lipid-lowering drugs, so it is necessary to know beneficial and adverse effects of these compounds on the body. The European Medicines Agencyís Committee for Medicinal Products for Human
Francik, Renata +2 more
core