Results 81 to 90 of about 14,040 (225)
International audienceBACKGROUND & AIMS: In patients with primary sclerosing cholangitis (PSC), ursodeoxycholic acid (UDCA) treatment improves serum liver tests and surrogate markers of prognosis but has no proven effect on survival. Additional therapies
Kemgang Fankem, Astrid Donald +9 more
core +1 more source
This study examined whether dipeptidyl peptidase 4 (DPP4) characteristics in peripheral blood monocytes relate to renal parameters. Monocyte DPP4 activity was independently associated with urinary albumin excretion in patients with type 2 diabetes, suggesting that monocytes may function as a cellular link between DPP4 and diabetic kidney disease ...
Hideyuki Okuma +2 more
wiley +1 more source
Use of fibrates in clinical practice: Queensland lipid group consensus recommendations
Background Fibrates have been prescribed for decades as `broad-spectrum' lipid modifying agents that can improve plasma levels of triglycerides, high-density lipoprotein cholesterol, and triglyceride-rich lipoproteins, including very low-and intermediate-
Hamilton-Craig, Ian +7 more
core +1 more source
Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study
ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai +5 more
wiley +1 more source
Role of fibrates in reducing coronary risk: a UK Consensus
This paper presents the consensus reached by a panel of experts on the role of fibrates in reducing coronary heart disease (CHD). The emphasis is on the application of these agents in clinical practice.
Byrne, Christopher D.
core +1 more source
Yi-Fen Lei,1,2 Hsiu-Chen Lin,3,4 Hsiu-Li Lin,5 Yow-Sheng Uang,2 Hui-Wen Cheng,2 Li-Hsuan Wang2,6 1Department of Pharmacy, Mackay Memorial Hospital, Taipei 10449, Taiwan; 2School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031 ...
Lei YF +5 more
doaj
Target trial emulation of a multi‐institutional electronic health record network showed comparable cardiorenal effectiveness and safety of dapagliflozin versus empagliflozin in adults with type 2 diabetes and advanced‐stage chronic kidney disease.
Shih‐Hsuan Lin +6 more
wiley +1 more source
Fibred fibration categories [PDF]
We introduce fibred type-theoretic fibration categories which are fibred categories between categorical models of Martin-Löf type theory. Fibred type-theoretic fibration categories give a categorical description of logical predicates for identity types. As an application, we show a relational parametricity result for homotopy type theory.
openaire +2 more sources
Chemical degradation kinetics of fibrates: bezafibrate, ciprofibrate and fenofibrate
Fibrates are drugs used for the treatment of hypertriglyceridemia and for the prevention of atherosclerosis. Three drugs in the fibrate class, ciprofibrate, fenofibrate and bezafibrate, were chosen for this study because their raw materials are readily ...
Marcelo Antonio de Oliveira +2 more
doaj +1 more source
Epoxy Clerodane Diterpene (ECD) significantly reduces adipocyte hypertrophy and lipid accumulation in human mesenchymal stem cell (hMSC)‐derived adipocytes. ECD improves mitochondrial membrane potential (ΔΨm), increases thermogenic regulators (UCP‐1, PPARγC1α), decreases adipogenic markers (C/EBPα, PPARγ), and reduces inflammatory mediators (TNF‐α, NF ...
Sahar Abdulaziz AlSedairy +4 more
wiley +1 more source

