Results 71 to 80 of about 14,825 (199)
Role of fibrates in reducing coronary risk: a UK Consensus
This paper presents the consensus reached by a panel of experts on the role of fibrates in reducing coronary heart disease (CHD). The emphasis is on the application of these agents in clinical practice.
Byrne, Christopher D.
core +1 more source
Fibrates are widely used hypolipidaemic agents that act as ligands of the peroxisome proliferator-activated receptor α (PPARα). p38 is a protein kinase that is mainly activated by environmental and genotoxic stress. We investigated the effect
Katerina Cizkova, Zdenek Tauber
core +1 more source
Update on the use of fibrates: focus on bezafibrate
Ilan Goldenberg1, Michal Benderly2, Uri Goldbourt2,31Heart Institute and 2Neufeld Cardiac Research Institute, Sheba Medical Center Tel Hashomer, Israel; 3Division of Epidemiology and Preventive Medicine, Sackler School of Medicine, Tel-Aviv University ...
Ilan Goldenberg +2 more
core
Fibred fibration categories [PDF]
We introduce fibred type-theoretic fibration categories which are fibred categories between categorical models of Martin-Löf type theory. Fibred type-theoretic fibration categories give a categorical description of logical predicates for identity types. As an application, we show a relational parametricity result for homotopy type theory.
openaire +2 more sources
Anti-atherogenic effects of fibrates in type 2 diabetes [PDF]
Type 2 diabetes is an increasing cause of premature coronary heart disease. Several trials with lipid-modifying therapy have included sufficient numbers of diabetics to indicate that treatment of diabetic dyslipidaemia with either fibrates or statins ...
Philip Barter +2 more
core +1 more source
Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels
Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt +3 more
doaj +1 more source
Classifying pro-fibrations and shape fibrations
We first describe some categories. Let TOP denote the category whose objects are topological spaces and whose morphisms are continuous maps. Let \(TOP^ N\) denote the category whose objects are the inverse systems in TOP indexed by the set of natural numbers \({\mathbb{N}}\) (with continuous bonding maps).
Hastings, Harold M., Waner, Stefan
openaire +2 more sources
Mechanism of action of fibrates on lipid and lipoprotein metabolism
Treatment with fibrates, a widely used class of lipid-modifying agents, results in a substantial decrease in plasma triglycerides and is usually associated with a moderate decrease in LDL cholesterol and an increase in HDL cholesterol concentrations ...
Staels, B. +5 more
core +1 more source
Fibrates and coronary risk reduction
Many medications are currently available to correct lipoprotein abnormalities when lifestyle measures alone are not sufficient. No single agent or class of agents is able to correct all of the lipoprotein abnormalities. This paper reviews the role of one
George Steiner
core
This analysis evaluates the effects on lipoprotein subfractions and LDL particle size of ezetimibe/simvastatin with or without coadministration of fenofibrate in patients with mixed hyperlipidemia.
Michel Farnier +4 more
doaj +1 more source

