Results 61 to 70 of about 14,825 (199)

Fibrates for primary prevention of cardiovascular disease events

, 2012
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the clinical benefit and harm of fibrates versus placebo or usual care or fibrates plus other lipid-modifying drugs versus other lipid-modifying drugs ...
Benjamin Kasenda, Ramon Saccilotto, Saccilotto, Ramon, Alain J Nordmann, Dirk Bassler, Nordmann, Alain J., Bassler, Dirk, Neera Bhatnagar, Matthias Briel, Ferreira-González, Ignacio, Briel, Matthias, Bhatnagar, Neera, Kasenda, Benjamin, Ignacio Ferreira-González   +13 more
core   +1 more source

Safety of Combined Statin and Fibrate Therapy: Risks of Liver Injury and Acute Kidney Injury in a Cohort Study from the Shizuoka Kokuho Database

Drugs - Real World Outcomes
Introduction Statins and fibrates are important means of preventing cardiovascular diseases, particularly when administered in combination as part of various therapeutic strategies.
Yohei Sobukawa, Taichi Hatta, Daito Funaki, Eiji Nakatani   +3 more
doaj   +1 more source

From Crisis to Diagnosis: A Case of Hypertriglyceridemic Pancreatitis as the First Clinical Presentation of Type 1 Diabetes [PDF]

Journal of Clinical and Diagnostic Research
Acute Pancreatitis (AP) is a prevalent and rapidly progressive inflammatory disorder of the pancreas, often presenting with abdominal pain and elevated serum pancreatic enzymes.
Subashini Vadivel, Sheetal Nandha Kishore, Jagannath S Dhadwad, Janvi Panchal   +3 more
doaj   +1 more source

Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates. [PDF]

Epidemiological and transgenic animal studies have implicated apo C-III as a major determinant of plasma triglyceride metabolism. Since fibrates are very efficient in lowering triglycerides, it was investigated whether fibrates regulate apo C-III gene ...
Saladin, R, Staels, B, Dallongeville, J, Auwerx, J, Fruchart, J C, Vu-Dac, N, Kosykh, V A   +6 more
core   +2 more sources

FIBRATES SEEM TO BE EQUALLY EFFECTIVE AS SECOND-LINE THERAPY IN PRIMARY BILIARY CHOLANGITIS, WITH BIOCHEMICAL RESPONSE PLATEAUING AT 6 MONTHS

Annals of Hepatology
Introduction and Objectives: Approximately 40% of patients with primary biliary cholangitis (PBC) exhibit an incomplete biochemical response to ursodeoxycholic acid (UDCA) and require second-line therapy.
Guilherme Grossi Lopes Cançado, María Lucía Ferraz, Debora Raquel Benedita Terrabuio, Alejandra Villamil, Lorena Castro Solari, Graciela Elia Castro-Narro, Ezequiel Ridruejo, Cristiane A. Villela-Nogueira, Malen L. Fernandes, Daniela Chiodi, Carla Enrique, Paulo Lisboa Bittencourt, Gustavo Pereira, Fernando Bessone, Eira Cerda, Rodrigo Zapata, Hugo Cheinquer, Álvaro Urzúa, Manuel Mendizabal, Liliana Sampaio Costa Mendes, Pablo Andrés Coste Murillo, Janaina L. Narciso-Schiavon, Fernanda A. Gelape, Vinicius A. Santos, Raimundo de Araujo Gama, Ana Cristina Amaral, Mario Guimarães Pessoa, Sarah Rufino, Eduardo Luiz Rachid Cançado, Andreína Fragens, Natalia Sobenko, Franco Weisser Vuskovic, Gabriel Mezzano Puentes, Mirta Peralta, Harlim Rodrigues, Lívia Villela Nogueira, Vivian Rotman, Federico Orozco, Nelia Hernandez, Claudia Alves Couto   +39 more
doaj   +1 more source

Hitchin fibrations are Ngô fibrations

We study the geometry of the Hitchin fibration for $\mathcal{L}$-valued $G$-Higgs bundles over a smooth projective curve of genus $g$, where $G$ is a reductive group and $\mathcal{L}$ is a suitably positive line bundle. We show that the Hitchin fibration admits the structure of a weak Abelian fibration. In the case when the line bundle $\mathcal{L}$ is
de Cataldo, Mark Andrea, Fringuelli, Roberto, Herrero, Andres Fernandez, Mauri, Mirko   +3 more
openaire   +2 more sources

Mirrorfolds with K3 fibrations

Journal of High Energy Physics, 2008
Eqns (2.61) and (3.17 ...
Kawai, Shinsuke, Sugawara, Yuji
openaire   +2 more sources

Primary sclerosing cholangitis response to the combination of fibrates with ursodeoxycholic acid: French–Spanish experience

, 2018
International audienceBACKGROUND & AIMS: In patients with primary sclerosing cholangitis (PSC), ursodeoxycholic acid (UDCA) treatment improves serum liver tests and surrogate markers of prognosis but has no proven effect on survival. Additional therapies
Kemgang Fankem, Astrid Donald, Poupon, Raoul, Housset, Chantal, Belkacem, Karima, Ben, Pares, Albert, Gaouar, Farid, Corpechot, Christophe, Chazouillères, Olivier, Lemoinne, Sara, Reig, Anna   +9 more
core   +1 more source

Association Between Use of Antihyperlipidemic Agents and Chronic Obstructive Pulmonary Disease in Patients with Hyperlipidemia: A Population-Based Retrospective Cohort Study

International Journal of COPD, 2020
Yi-Fen Lei,1,2 Hsiu-Chen Lin,3,4 Hsiu-Li Lin,5 Yow-Sheng Uang,2 Hui-Wen Cheng,2 Li-Hsuan Wang2,6 1Department of Pharmacy, Mackay Memorial Hospital, Taipei 10449, Taiwan; 2School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031 ...
Lei YF, Lin HC, Lin HL, Uang YS, Cheng HW, Wang LH   +5 more
doaj  

Chemical degradation kinetics of fibrates: bezafibrate, ciprofibrate and fenofibrate

Brazilian Journal of Pharmaceutical Sciences
Fibrates are drugs used for the treatment of hypertriglyceridemia and for the prevention of atherosclerosis. Three drugs in the fibrate class, ciprofibrate, fenofibrate and bezafibrate, were chosen for this study because their raw materials are readily ...
Marcelo Antonio de Oliveira, Gerliane Damázio da Silva, Michele Soares Tacchi Campos   +2 more
doaj   +1 more source