Results 41 to 50 of about 14,040 (225)
Since the description of the synthetic chemical clofibrate in 1962, various derivatives of fibrates with a diversity of chemical structures have been developed. Several of these are used clinically to treat dyslipidemia because they are generally effective in lowering elevated plasma triglycerides and cholesterol.
Ganesaratnam K, Balendiran +2 more
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Searching for K3 fibrations [PDF]
21 pages, LaTeX2e, 4 eps figures, uses packages amssymb,latexsym,cite ...
Avram, A. C. +3 more
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Introduction and Objectives: Seladelpar was evaluated as monotherapy or with ursodeoxycholic acid in RESPONSE (NCT04620733) among patients with primary biliary cholangitis.
Alejandra M. Villamil +9 more
doaj +1 more source
Fibrations and recursivity [PDF]
This paper, a contribution to category-theoretic recursion theory, uses the language of fibred categories and presheaves to formulate abstract versions of some results from the classical theory. In particular, this work generalizes that of \textit{P. S. Mulry} [``Generalized Banach-Mazur functionals in the topos of recursive sets,'' J.
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Fibrations of AU-contexts beget fibrations of toposes
Suppose an extension map $U\colon \mathbb{T}_1 \to \mathbb{T}_0$ in the 2-category $\mathfrak{Con}$ of contexts for arithmetic universes satisfies a Chevalley criterion for being an (op)fibration in $\mathfrak{Con}$. If $M$ is a model of $\mathbb{T}_0$ in an elementary topos $\mathcal{S}$ with nno, then the classifier $p\colon\mathcal{S}[\mathbb{T}_1/M]
Hazratpour, Sina, Vickers, Steven
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PPARγ agonists are implicated in the regulation of diabetes and metabolic syndrome and have therapeutic potential in brain disorders. PPARγ modulates appetite through its central effects, especially on the hypothalamic arcuate nucleus (ARC).
Annalisa Chiavaroli +5 more
doaj +1 more source
Mode d’action moléculaire des fibrates
Les fibrates correspondent à des molécules découvertes et utilisées depuis de nombreuses années, connus pour présenter des effets pléiotropiques sur le métabolisme des lipides.
Patrick Duriez +2 more
core +1 more source
Induction of 1-Acylglycerophosphocholine Acyltransferase Genes by Fibrates in the Liver of Rats [PDF]
The effect of fibrates (clofibric acid, bezafibrate and fenofibrate) on the gene expression and activity of 1-acylglycerophosphocholine acyltransferase (LPCAT) was investigated.
川嶋, 洋一 +7 more
core +1 more source
Statin and fibrate associed myopathy: study of eight patients [PDF]
Lipid-lowering drugs have been occasionally associated with neuromuscular symptoms and muscle biopsy changes. We reported the clinical course and the muscle biopsy in eight patients with hyperlipoproteinemia, treated with lipid -lowering drugs (statins ...
Alzira A. Siqueira Carvalho +2 more
doaj +1 more source
The most documented fibrates are gemfibrozil, clofibrate and bezafibrate, while for statins, the majority of the published literature focuses on atorvastatin and simvastatin.
Manuel Blonç +5 more
doaj +1 more source

