Results 51 to 60 of about 14,825 (199)

Fibrates in the prevention of cardiovascular disease in patients with type 2 diabetes mellitus: meta-analysis of randomised controlled trials

open access: yes, 2006
To assess the impact of lipid lowering treatment with fibrates on cardiovascular endpoints in patients with type 2 diabetes ...
Allemann, Sabin   +4 more
core   +1 more source

Induction of 1-Acylglycerophosphocholine Acyltransferase Genes by Fibrates in the Liver of Rats [PDF]

open access: yes, 2012
The effect of fibrates (clofibric acid, bezafibrate and fenofibrate) on the gene expression and activity of 1-acylglycerophosphocholine acyltransferase (LPCAT) was investigated.
川嶋, 洋一   +7 more
core   +1 more source

Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review

open access: yesCardiovascular Diabetology, 2005
Background The importance of low high-density lipoprotein cholesterol (HDL-C), elevated non HDL-C (as part of the metabolic syndrome, prediabetes, and type 2 diabetes mellitus), and an isolated low HDL-C is rapidly emerging. The antiatherosclerotic roles
Tyagi Suresh C, Hayden Melvin R
doaj   +1 more source

Fenofibrate (a PPAR-α Agonist) Administered During Ethanol Withdrawal Reverts Ethanol-Induced Astrogliosis and Restores the Levels of Glutamate Transporter in Ethanol-Administered Adolescent Rats

open access: yesFrontiers in Pharmacology, 2021
High-ethanol intake induces a neuroinflammatory response, which has been proposed as responsible for the maintenance of chronic ethanol consumption. Neuroinflammation decreases glutamate transporter (GLT-1) expression, increasing levels of glutamate that
Francisca Villavicencio-Tejo   +4 more
doaj   +1 more source

Mécanismes d'action des statines et des fibrates

open access: yes, 2007
Les statines et les fibrates constituent les deux classes majeures d'hypolipémiants. Les statines sont utilisées dans le traitement des hypercholestérolémies essentielles et des hyperlipidémies mixtes, alors que les fibrates sont employés dans celui des ...
Patrick Duriez
core   +1 more source

Lipid-lowering therapy in the outpatient practice

open access: yesМедицинский совет, 2013
The review focuses on the importance of primary and secondary prevention of cardiovascular disease in outpatient settings, and principles of effective and safe use of modern lipid-lowering drugs.
S. A. Urazgildeyeva
doaj   +1 more source

Current and future opportunities for the management of primary biliary cholangitis

open access: yesFrontiers in Gastroenterology, 2023
Primary biliary cholangitis (PBC) is a rare immune-mediated chronic cholestatic liver disease that can progress to liver fibrosis and, ultimately, cirrhosis if left untreated.
Sandra Naffouj, Jennifer Wang
doaj   +1 more source

Fibrations of graphs

open access: yesDiscrete Mathematics, 2002
A fibration of graphs is a morphism that is a local ismorphism of in-neighbourhoods, much in the same way a covering projection is a local isomorphism of neighbourhoods. The authors develop systematically the theory of graph fibrations, with a special emphasis on results related to some applications in computer science.
P. Boldi, S. Vigna
openaire   +3 more sources

Inhibitory action of gemfibrozil on cholesterol absorption in rat intestine

open access: yesJournal of Lipid Research, 2001
This study was designed to determine whether gemfibrozil inhibits intestinal lipid absorption. Male Sprague-Dawley rats received an oral dose of 30 mg gemfibrozil/kg body weight for 14 days.
Yoh Umeda   +6 more
doaj   +1 more source

Flavonoids and fibrate modulate apoE4-induced processing of amyloid precursor protein in neuroblastoma cells

open access: yesFrontiers in Neuroscience, 2023
IntroductionApolipoprotein (apo) E4, being a major genetic risk factor for Alzheimer’s disease (AD), is actively involved in the proteolytic processing of amyloid precursor protein (APP) to amyloid β (Aβ) peptide, the principle constituent of amyloid ...
Viralkumar Davra, Kenza E. Benzeroual
doaj   +1 more source

Home - About - Disclaimer - Privacy