Results 41 to 50 of about 12,053 (162)
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Cardiovascular Diabetology, 2005 Background The importance of low high-density lipoprotein cholesterol (HDL-C), elevated non HDL-C (as part of the metabolic syndrome, prediabetes, and type 2 diabetes mellitus), and an isolated low HDL-C is rapidly emerging. The antiatherosclerotic roles
Tyagi Suresh C, Hayden Melvin R
doaj +1 more source
Antioxidants, 2023 High ethanol consumption triggers neuroinflammation, implicated in sustaining chronic alcohol use. This inflammation boosts glutamate, prompting dopamine release in reward centers, driving prolonged drinking and relapse.
Cristina Ibáñez +5 more
doaj +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Lipid-lowering therapy in the outpatient practice
Медицинский совет, 2013 The review focuses on the importance of primary and secondary prevention of cardiovascular disease in outpatient settings, and principles of effective and safe use of modern lipid-lowering drugs.
S. A. Urazgildeyeva
doaj +1 more source
Pharmaceuticals, 2021 Common pathophysiological mechanisms have emerged for different neurological and neuropsychiatric conditions. In particular, mechanisms of oxidative stress, immuno-inflammation, and altered metabolic pathways converge and cause neuronal and non-neuronal ...
Claudia Sagheddu +3 more
doaj +1 more source
Inhibitory action of gemfibrozil on cholesterol absorption in rat intestine
Journal of Lipid Research, 2001 This study was designed to determine whether gemfibrozil inhibits intestinal lipid absorption. Male Sprague-Dawley rats received an oral dose of 30 mg gemfibrozil/kg body weight for 14 days.
Yoh Umeda +6 more
doaj +1 more source
Effects of Hypolipidemic Drugs on Psoriasis
Metabolites, 2023 Psoriasis is a chronic, systematic, inflammatory disease in which multiple metabolic and immunologic disturbances lead to lipid abnormalities, impaired glucose tolerance, metabolic syndrome, diabetes mellitus, atherosclerosis, hypertension, ischemic ...
Mateusz Matwiejuk +4 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Tommaso Braga +2 more
wiley +1 more source
Diagonal fibrations are pointwise fibrations
, 2007 to be published in "Journal of Homotopy and Related Structures"
Cegarra, A. M., Remedios, J.
openaire +3 more sources