Results 71 to 80 of about 12,053 (162)

The usefulness of information on HDL-cholesterol: potential pitfalls of conventional assumptions

open access: yesCurrent Controlled Trials in Cardiovascular Medicine, 2001
Treatment decisions related to disease prevention are often based on two conventional and related assumptions. First, an intervention-induced change in a surrogate marker (such as high-density lipoprotein [HDL]-cholesterol) in the desired direction ...
Furberg Curt D
doaj   +1 more source

Comparative effectiveness of combination therapy with SGLT‐2 inhibitors and GLP‐1 RAs compared with SGLT‐2 inhibitors in individuals with type 2 diabetes: A prevalent new‐user cohort study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3273-3284, April 2026.
Abstract Aims To evaluate the effectiveness of combination therapy with sodium‐glucose cotransporter 2 (SGLT‐2) inhibitors and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) compared with continued SGLT‐2 inhibitor therapy in routine practice among individuals with type 2 diabetes.
Gregor A. Maier   +3 more
wiley   +1 more source

Classifying pro-fibrations and shape fibrations

open access: yesJournal of Pure and Applied Algebra, 1986
We first describe some categories. Let TOP denote the category whose objects are topological spaces and whose morphisms are continuous maps. Let \(TOP^ N\) denote the category whose objects are the inverse systems in TOP indexed by the set of natural numbers \({\mathbb{N}}\) (with continuous bonding maps).
Hastings, Harold M., Waner, Stefan
openaire   +2 more sources

Pharmacokinetic Comparison Between a Fixed‐Dose Combination of Atorvastatin/Fenofibrate 20/145 mg and the Corresponding Individual Components

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.
Abstract Co‐administration of atorvastatin and fenofibrate has demonstrated clinical benefits in patients with dyslipidemia. To improve convenience and adherence, a fixed‐dose combination (FDC) of the two agents has gained interest. This study aimed to compare the pharmacokinetics (PKs) and safety of an FDC of atorvastatin/fenofibrate 20/145 mg with ...
Seungri Lee   +6 more
wiley   +1 more source

Piecewise linear fibrations [PDF]

open access: yesPacific Journal of Mathematics, 1987
A PL \((=\) piecewise linear) fibration is a Hurewicz fibration p: \(E\to B\) such that E, B are compact polyhedra and p is a PL map. Very important examples are PL manifold bundles (i.e. PL locally trivial bundles whose fibers are compact PL manifolds with boundary). The present paper establishes a PL link between the category of PL fibrations and the
openaire   +3 more sources

Early Identification of Cardiovascular Adverse Events Associated With Rofecoxib Using Real‐World Data From the UK: A Nested Case–Control and Case‐Crossover Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Background Traditional pharmacovigilance systems have limitations in detecting common adverse drug reactions. We investigated whether real‐world data (RWD) could have detected rofecoxib's cardiovascular adverse effects earlier using nested case–control (NCC) and case‐crossover (CCO) designs.
Donya Moslemzadeh   +5 more
wiley   +1 more source

Opposite metabolic response to fenofibrate treatment in pregnant and virgin rats

open access: yesJournal of Lipid Research, 2002
The level of maternal circulating triglycerides during late pregnancy has been correlated to newborns' weight in humans. To investigate the response to fenofibrate, a hypotriglyceridemic agent, in pregnant rats, 0, 100, or 200 mg of fenofibrate/kg body ...
Ana Soria, Carlos Bocos, Emilio Herrera
doaj   +1 more source

Efficacy of probiotics (Bifidobacterium bifidum G9‐1) in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation: An exploratory, multicenter, open‐label, single‐arm study (BIRDIE study)

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 3, Page 470-482, March 2026.
Bifidobacterium bifidum G9‐1 improved stool form, defecation frequency, and Quality of Life in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation. ABSTRACT Introduction Although constipation is a major complication of type 2 diabetes mellitus and chronic kidney disease, evidence for its treatment in these ...
Fuki Ikeda   +10 more
wiley   +1 more source

The Pleiotropic Effects of Lipid-Modifying Interventions: Exploring Traditional and Emerging Hypolipidemic Therapies

open access: yesMetabolites
Atherosclerotic cardiovascular disease poses a significant global health issue, with dyslipidemia standing out as a major risk factor. In recent decades, lipid-lowering therapies have evolved significantly, with statins emerging as the cornerstone ...
Dimitris Kounatidis   +10 more
doaj   +1 more source

Lie algebroid fibrations

open access: yesAdvances in Mathematics, 2011
28 pages, 1 ...
Brahic, Olivier, Zhu, Chenchang
openaire   +4 more sources

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