Results 11 to 20 of about 187,834 (297)

Fibril Breaking Accelerates α-Synuclein Fibrillization [PDF]

open access: yesThe Journal of Physical Chemistry B, 2015
The formation of amyloid fibrils of α-synuclein (αSyn), the key protein in Parkinson's disease, is an autocatalytic process that is seeded by mature αSyn fibrils. Based on systematic measurements of the dependence of the fibril growth rate on the concentrations of monomers and preformed fibrillar seeds, we propose a mechanism of αSyn aggregation that ...
Shvadchak, Volodymyr V.   +2 more
openaire   +4 more sources

Atrial fibrillation [PDF]

open access: yesNature Reviews Disease Primers, 2016
Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, and increases in prevalence with increasing age and the number of cardiovascular comorbidities. AF is characterized by a rapid and irregular heartbeat that can be asymptomatic or lead to symptoms such as palpitations, dyspnoea and dizziness.
Lip, Gregory   +10 more
  +14 more sources

Atrial fibrillation

open access: yesAustralian Journal of General Practice, 2019
Atrial fibrillation (AF) is increasingly common among Australia's ageing population and carries significant morbidity and mortality. Its detection through screening, cardiac device interrogation and/or symptoms of AF brings with it a number of significant clinical issues.The aim of this article is to outline a systematic approach to the management of ...
Kunal Pradip, Verma, Michael, Wong
openaire   +5 more sources

Atrial Fibrillation [PDF]

open access: yesHeart Lung <html_ent glyph="@amp;" ascii="&amp;"/> Circulation, 2003
Atrial fibrillation (AF) is a hetrogeneous disease that may present in many forms. Advances in our understanding of the mechanism responsible for AF have led to exciting new therapies that may soon provide a definitive cure.
openaire   +4 more sources

DNAJB9 Is a Reliable Immunohistochemical Marker of Fibrillary Glomerulonephritis: Evaluation of Diagnostic Efficacy in a Large Series of Kidney Biopsies

open access: yesBiomedicines, 2022
Fibrillary glomerulonephritis (FGN) is a rare glomerular disease characterized by a challenging diagnostic workup requiring ultrastructural identification of 20 nm-thick randomly oriented fibrillar deposits.
Alessandro Gambella   +9 more
doaj   +1 more source

Structure-mechanics relationships of collagen fibrils in the Osteogenesis Imperfecta Mouse model [PDF]

open access: yes, 2015
The collagen molecule, which is the building block of collagen fibrils, is a triple helix of two α1(I) chains and one α2(I) chain. However, in the severe mouse model of osteogenesis imperfecta (OIM), deletion of the COL1A2 gene results in the ...
Andriotis, OG   +7 more
core   +4 more sources

A viscoelastic theory of turbulent fluid permeated with fibril magnetic fields [PDF]

open access: yes, 2003
The solar convection zone is a turbulent plasma interacting with a magnetic field. Its magnetic field is often described as fibrillar since it consists of slender flux tubes occupying a small fraction of the total volume.
Fisher, G.H.   +2 more
core   +1 more source

Effect of Fibril Entanglement on Pickering Emulsions Stabilized by Whey Protein Fibrils for Nobiletin Delivery

open access: yesFoods, 2022
The aim of the study was to investigate the effects of whey protein isolate (WPI) fibrils entanglement on the stability and loading capacity of WPI fibrils-stabilized Pickering emulsion.
Fangcheng Jiang   +5 more
doaj   +1 more source

Dynamics of internetwork chromospheric fibrils: Basic properties and MHD kink waves [PDF]

open access: yes, 2017
Using the spectroscopic imaging capabilities of the Swedish Solar Telescope, we aim to provide the first investigation on the nature and dynamics of elongated absorption features (fibrils) observed in H$\alpha$ in the internetwork.
Henriques, V.   +2 more
core   +2 more sources

Phenol-Soluble Modulins Modulate Persister Cell Formation in Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2020
Staphylococcus aureus is a human pathogen that can cause chronic and recurrent infections and is recalcitrant to antibiotic chemotherapy. This trait is partly attributed to its ability to form persister cells, which are subpopulations of cells that are ...
Mara Baldry   +6 more
doaj   +1 more source

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