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The Fibrinolytic System in Children
Seminars in Thrombosis and Hemostasis, 2003The fibrinolytic system comprises a cascade of serine proteinase activation events that culminate in the generation of plasmin and, subsequently, degradation of fibrin. Although all components of the fibrinolytic system are present at birth, plasma concentrations of key components in infants and children differ physiologically from those in adults ...
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Elements of the Fibrinolytic System
Annals of the New York Academy of Sciences, 2001Abstract: The blood fibrinolytic system comprises an inactive proenzyme, plasminogen, that can be converted to the active enzyme, plasmin. Plasmin degrades fibrin into soluble fibrin degradation products, by two physiological plasminogen activators (PA), the tissue type PA (t‐PA) and the urokinase type PA (u‐PA).
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