Results 91 to 100 of about 4,822,589 (177)

LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-α stimulation

, 2018
Summary This study examined the expression of the inhibitory receptor, leucocyte-associated immunoglobulin (Ig)-like receptor-1 (LAIR-1) in fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA) patients to investigate its ...
X Yi, X Liu, Y Ding, J Zhang, H Dong, R Zhuang, S Wang, Y Zhang   +7 more
core   +1 more source

Immunological Roles of Fibroblast-Like Synoviocyte Cells in Rheumatoid Arthritis [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Fibroblast-like synoviocytes (FLS), also known as synovial fibroblasts or type B synoviocytes, are the primary cells responsible for the structure of the synovial lining.
Mohammad Reza Royaei, Mohammad Taher Tahoori   +1 more
doaj  

Functional expression of the chemokine receptor CCR7 on fibroblast-like synoviocytes

, 2008
Objectives. We have characterized the expression and the function of the chemokine receptor CCR7 on fibroblast-like synoviocytes (FLS) of patients with RA and OA and on dermal fibroblasts. Methods.
Schölmerich, J., Brühl, H., Lochbaum, D., Straub, R. H., Mack, M., Niedermeier, M.   +5 more
core   +1 more source

Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis

主査 : 亀田秀人 / タイトル : Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis /著者 : Hiroshi Sato, Sei Muraoka, Natsuko Kusunoki, Shotaro Masuoka, Soichi Yamada, Hideaki Ogasawara, Toshio Imai ...
佐藤, 洋志, サトウ, ヒロシ, Sato, Hiroshi   +2 more
core   +1 more source

Caveolae/lipid rafts in fibroblast-like synoviocytes: ectopeptidase-rich membrane microdomains

, 2001
Udgivelsesdato: 2001-Feb-15Membrane peptidases play important roles in cell activation, proliferation and communication. Human fibroblast-like synoviocytes express considerable amounts of aminopeptidase N/CD13, dipeptidyl peptidase IV/CD26, and ...
Riemann, D, Santos, A N, Danielsen, E M, Niels-Christiansen, L, Immerdal, Lissi, Thorsen, Evy, Kehlen, A, Langner, J, Hansen, Gert Helge   +8 more
core   +1 more source

Fibroblast-like synoviocyte-chondrocyte interaction in cartilage degradation

, 2007
Objective: In vitro models for joint diseases often focus on a single cell type, such as chondrocytes in osteoarthritis (OA) or fibroblast-like synoviocytes (synoviocytes) in rheumatoid arthritis (RA). However, these joint diseases affect the whole joint
Ronday, H.K., Huizinga, T.W.J., Steenvoorden, M.M.C., Bank, R.A., Groot, J. de, Toes, R.E.M.   +5 more
core  

siRNA therapy in osteoarthritis: targeting cellular pathways for advanced treatment approaches

Frontiers in Immunology
Osteoarthritis (OA) is a common joint disorder characterized by the degeneration of cartilage and inflammation, affecting millions worldwide. The disease’s complex pathogenesis involves various cell types, such as chondrocytes, synovial cells ...
Yunshen Li, Yunshen Li, Yunshen Li, Jianan Zhao, Jianan Zhao, Jianan Zhao, Shicheng Guo, Dongyi He, Dongyi He, Dongyi He   +9 more
doaj   +1 more source

Acylcarnitine enrichment as a characteristic of rheumatoid arthritis fibroblast-like synoviocyte metabolic fingerprint

Journal of Translational Autoimmunity
Objective: In rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLS) alter their metabolism to support their activation. We aimed to analyse the full spectrum of metabolic alterations associated with RA by performing untargeted metabolomics in RA ...
Georgios K. Vasileiadis, Yuan Zhang, Marion Laudette, Tahzeeb Fatima, Anna-Karin Hultgård Ekwall, Reshmi Sureshkumar, Ronald van Vollenhoven, Jon Lampa, Bjorn Gudbjornsson, Espen A. Haavardsholm, Dan Nordström, Gerdur Gröndal, Kim Hørslev-Petersen, Kristina Lend, Merete L. Hetland, Michael Nurmohamed, Mikkel Østergaard, Till Uhlig, Tuulikki Sokka-Isler, Anna Rudin, Jan Borén, Monica Guma, Cristina Maglio   +22 more
doaj   +1 more source

PHARMACOLOGICAL CHARACTERIZATION OF PURINE RECEPTORS IN BOVINE AND HUMAN CHONDROCYTES AND FIBROBLAST-LIKE SYNOVIOCYTES.

, 2010
Chronic inflammation is an important factor in the pathology of different forms of joint diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA).
TOSI, Alice
core  

ADAM8 silencing suppresses the migration and invasion of fibroblast-like synoviocytes via FSCN1/MAPK cascade in osteoarthritis

Arthritis Research & Therapy
Objective Osteoarthritis (OA) is a degenerative joint disease that affects elderly populations worldwide, causing pain and disability. Alteration of the fibroblast-like synoviocytes (FLSs) phenotype leads to an imbalance in the synovial inflammatory ...
Kai Chen, Huaqiang Tao, Pengfei Zhu, Miao Chu, Xueyan Li, Yi Shi, Liyuan Zhang, Yaozeng Xu, Shujun Lv, Lixin Huang, Wei Huang, Dechun Geng   +11 more
doaj   +1 more source