Results 111 to 120 of about 18,476 (229)
Glycophenotyping of osteoarthritic fibroblast-like synoviocytes [PDF]
Osteoarthritis and Cartilage, 2020 S. Toegel +7 more
openaire +1 more source
Orexin A may suppress inflammatory response in fibroblast-like synoviocytes
Biomedicine & Pharmacotherapy, 2018 Orexins are peptides found in the hypothalamus and other peripheral tissues including adipose tissue, the endocrine cells of the gut, adrenal gland testis, and the pancreas. They play important roles in neuro-protection by inhibiting oxidative stress and inflammatory response via their type 1 and 2 receptors (OX1R and OX2R). The expressions of OX1R and
Minghui, Sun +4 more
openaire +2 more sources
Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
The emerging fibroblast‐like synoviocyte channelome [PDF]
Experimental Physiology, 2018 Simon R. Tew, Richard Barrett‐Jolley
openaire +3 more sources
Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.ABSTRACT Objective We examined the effectiveness of combining nanochitosan Black Soldier Fly (BSF) pupae and demineralized dentin matrix (DDM) for accelerated bone remodeling by path analysis of osteoblasts, OPG, osteocalcin (OCN), osteoclasts, and RANKL.
Renie Kumala Dewi +8 more
wiley +1 more source
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada +9 more
core +1 more source
Journal of Orthopaedic Research, Volume 44, Issue 4, April 2026.ABSTRACT Dysregulation of synovial homeostasis has been implicated in the pathophysiology of osteoarthritis (OA), but the effects that cigarette smoking has on OA‐affected synovium have yet to be studied. To further the knowledge on how cigarette smoke alters OA progression, we investigated the direct effects of cigarette smoke extract (CSE) on ...
Emily Sawvell DiNicola +3 more
wiley +1 more source
Oridonin suppresses autophagy and survival in rheumatoid arthritis fibroblast-like synoviocytes
Pharmaceutical Biology, 2020 Context Oridonin exhibits various pharmacological and physiological activities, including antioxidant, antibacterial, anti-inflammatory, pro-apoptotic, anticancer and neurological effects.
Shou-Di He +7 more
doaj +1 more source
Osteoarthritis: Epidemiology, Pathogenesis, and Treatment
MedComm, Volume 7, Issue 4, April 2026.Osteoarthritis is a prevalent degenerative joint disease with a growing global burden. Its development involves complex interactions among epidemiological factors, pathological changes, molecular signaling, and epigenetic regulation. Understanding these mechanisms provides insights into disease progression and supports the development of therapeutic ...
Tianrui Chen +8 more
wiley +1 more source
Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes
Experimental Biology and Medicine, 2011 Activated rheumatoid arthritis fibroblast-like synoviocytes (RAFLSs) play an important role in the initiation and progression of rheumatoid arthritis (RA). Rapid proliferation and defective apoptosis of RAFLSs are two main mechanisms contributing to synovial hyperplasia.
Xiu-hua, Wang +2 more
openaire +2 more sources