Results 121 to 130 of about 5,296,642 (245)

Configuration‐Encoded Cell Alignment by Light‐Gated Silicon Photovoltaic Microcell Arrays

Advanced Functional Materials, EarlyView.
Light‐gated silicon photovoltaic microcells convert pulsed illumination into localized electrical cues. Arranging otherwise similar microcells into four‐lobed, six‐lobed, or circular patterns directs fibroblasts into corresponding local arrangements without wired stimulation.
Yifan Tao, Ilayda Namli, Joseph Christakiran Moses, Youdi Liu, Suihong Liu, Syed Hasan Askari Rizvi, Yasar Ozer Yilmaz, Ibrahim T. Ozbolat   +7 more
wiley   +1 more source

FAPI in radionuclide theranostics: toward a new emerging paradigm for tumor management

肿瘤影像学
Radionuclide imaging targeting fibroblast activation protein inhibitor (FAPI) has shown notable advantages in the early diagnosis and staging of various tumors.
Ying DING, Hui YANG
doaj  

Hydrostatic pressure regulates glutamine metabolism to promote bladder fibroblast activation via the Piezo1/YAP1/GLS1 axis

Journal of Translational Medicine
Background Bladder outlet obstruction (BOO), initiated by abnormal mechanical stress, leads to progressive bladder fibrosis and functional decompensation.
Kang Li, Pengyu Wei, Zhipeng Li, Wenbo Kuang, Mengyang Zhang, Changcheng Luo, Kai Cui, Dongxu Lin, Zhong Chen   +8 more
doaj   +1 more source

Increased synovial and entheseal fibroblast activation detected by 68Ga-FAPI-PET/CT is associated with the development of psoriatic arthritis in psoriasis patients with arthralgia

RMD Open
Objectives To assess the clinical and imaging characteristics associated with fibroblast activation detected by 68Gallium-labelled fibroblast activation protein inhibitor positron emission tomography/CT (68Ga-FAPI-PET/CT) in patients with psoriasis and ...
Georg Schett, Andreas Ramming, Filippo Fagni, Christian Schmidkonz, Armin Atzinger, Torsten Kuwert, Michael Sticherling, Koray Tascilar, Sara Bayat, Maria Gabriella Raimondo, Melek Yalcin Mutlu, Rita Noversa de Sousa, Giulia Corte, Alp Temiz   +13 more
doaj   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

HMGB1-mediated macrophage polarization to M2 phenotype promotes ureteral stricture: therapeutic potential of HMGB1 inhibitors

European Journal of Medical Research
Background Ureteral stricture is a common condition characterized by fibrotic narrowing of the ureter, often resulting in obstruction and impaired renal function.
Jie Zheng, Lingsong Tao, Yingqing Liu, Yang Zhang, Li Cheng, Zongyao Hao   +5 more
doaj   +1 more source

Recent clinical advances in fibroblast activation protein targeted radioligand therapy for solid tumors

Frontiers in Nuclear Medicine
Fibroblast activation protein (FAP) is a type II transmembrane serine protease predominantly expressed by cancer-associated fibroblasts (CAFs) in more than 90% of epithelial malignancies.
Xiaolong Wu, Yu Wang, Yingchun Li, Wenli Hu   +3 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Cloning strategies for the isolation of an a-amylase inhibitor/endochitinase gene from the seeds of Coix lachryma-jobi [PDF]

, 1993
The aim of this work was to isolate the gene encoding a bifunctional a-amylase inhibitor/endochitinase protein from the seeds of Coix lachryma-jobi, a tropical cereal.
Fairweather, Donna, Fairweather, D
core  

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source