Results 11 to 20 of about 316,930 (256)
Prognostic Utility of Circulating Growth Factors in Aortic Valve Stenosis: A Pilot Study
Medicina, 2021 Background and Objectives: Aortic valve stenosis (AS) develops with a pronounced local inflammatory response, where a variety of growth factors are involved in the process, and may have a pro-inflammatory and anti-inflammatory effect.
Juris Hofmanis +9 more
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Pharmaceutics, 2021 Basic fibroblast growth factor (FGF-2) is a highly labile protein with strong potential for tissue engineering. The aim of this study was to develop FGF-2 formulations that are stable against physical stressors encountered in pharmaceutical processing ...
Leah R. Benington +3 more
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Fibroblast growth factor 2 (FGF2) [PDF]
Science-Business eXchange, 2009 Epileptogenesis and epilepsy progression are associated with rearrangements of neuronal circuits mediated by such processes as sprouting, neuronal cell death, and neurogenesis. These processes lead to hyperexcitability, spontaneous seizures, and/or worsening of seizure severity/frequency. Neurotrophic factors, and the Fibroblast Growth Factor-2 (FGF-2)
SIMONATO, Michele, ZUCCHINI, Silvia
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Effects of Fibroblast Growth Factor-2 on Longitudinal Bone Growth* [PDF]
Endocrinology, 1998 In vivo, fibroblast growth factor-2 (FGF-2) inhibits longitudinal bone growth. Similarly, activating FGF receptor 3 mutations impair growth in achondroplasia and thanatophoric dysplasia. To investigate the underlying mechanisms, we chose a fetal rat metatarsal organ culture system that would maintain growth plate histological architecture.
E E, Mancilla +4 more
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Retraction Note: Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes [PDF]
Arthritis Research & TherapyDongyao Yan +6 more
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Intracellular trafficking of endogenous fibroblast growth factor‐2 [PDF]
The FEBS Journal, 2008 We have previously reported how the release of fibroblast growth factor‐2 (FGF‐2) is mediated by shed vesicles. In the present study, we address the question of how newly synthesized FGF‐2 is targeted to the budding vesicles. Considering that in vitro cultured Sk‐Hep1 hepatocarcinoma cells release FGF‐2 and shed membrane vesicles only when cultured in ...
Taverna Simona +3 more
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Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice
Disease Models & Mechanisms, 2021 People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the role ...
Jharna R. Das +5 more
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Incorporation of FGF-2 into Pharmaceutical Grade Fucoidan/Chitosan Polyelectrolyte Multilayers
Marine Drugs, 2020 Biopolymer polyelectrolyte multilayers are a commonly studied soft matter system for wound healing applications due to the biocompatibility and beneficial properties of naturally occurring polyelectrolytes.
Natalie L. Benbow +3 more
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Fibroblast growth factor 2 isoforms and cardiac hypertrophy [PDF]
Cardiovascular Research, 2004 Fibroblast growth factor 2 (FGF-2), a multifunctional polypeptide that affects cell growth and differentiation and becomes upregulated by stress, is expressed as AUG-initiated 18 kDa FGF-2 or CUG-initiated 21-34 kDa (hi-FGF-2) isoforms. Animal models have provided strong evidence that FGF-2 is essential for the manifestation of overload- and ...
Elissavet, Kardami +6 more
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Case Reports in Oncology, 2020 Pulmonary tumor thrombotic microangiopathy (PTTM) is characterized by tumor cell microemboli with occlusive fibrointimal remodeling in small pulmonary vessels.
Yusuke Kawanaka +7 more
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