Results 31 to 40 of about 316,930 (256)

Prostaglandins Regulate the Expression of Fibroblast Growth Factor-2 in Bone [PDF]

Endocrinology, 1999
We examined the effect of PGs, particularly PGF2alpha, on basic fibroblast growth factor-2 (FGF-2) messenger RNA (mRNA) and protein in the rat osteoblastic cell line Py1a and in fetal rat calvariae. Py1a cells expressed multiple FGF-2 mRNA transcripts. PGF2alpha dose-dependently increased the 6-kb transcript at 6 h.
SABBIETI, Maria Giovanna, MARCHETTI, Luigi, ABREU C., MONTERO A., HAND A. R, RAISZ L. G., HURLEY M. M.   +6 more
openaire   +3 more sources

Role of Lactoferrinin Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor in Gingival Wounds [PDF]

Journal of Krishna Institute of Medical Sciences University, 2019
Background: Lactoferrin possesses the ability to promote migration and proliferation of fibroblasts which represents one potential reason for the use of lactoferrin to accelerate the healing process in gingival wounds.
Istiati, Intan Nirwana, Indra Surjono, Meircurius Dwi Condro Surboyo   +3 more
doaj  

FGF2 (fibroblast growth factor 2 (basic)) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FGF2 (fibroblast growth factor 2 (basic)), with data on DNA, on the protein encoded, and where the gene is implicated.
MacFarlane, LA, Murphy, P
openaire   +2 more sources

Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients

Journal of Translational Medicine, 2011
Background Non-gastrointestinal stromal tumor soft-tissue sarcomas (non-GIST STSs) constitute a heterogeneous group of tumors with poor prognosis. Fibroblast growth factor 2 (FGF2) and fibroblast growth factor receptor-1 (FGFR-1), in close interplay with
Smeland Eivind, Sorbye Sveinung W, Valkov Andrej, Kilvaer Thomas K, Bremnes Roy M, Busund Lill-Tove, Donnem Tom   +6 more
doaj   +1 more source

Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice

Scientific Reports, 2021
Fibroblast growth factor 2 (FGF2) is important in musculoskeletal homeostasis, therefore the impact of reduction or Fgf2 knockout on skeletal muscle function and phenotype was determined.
C. Homer-Bouthiette, L. Xiao, Marja M. Hurley   +2 more
doaj   +1 more source

Essential growth factor receptors for fibroblast homeostasis and activation: Fibroblast Growth Factor Receptor (FGFR), Platelet Derived Growth Factor Receptor (PDGFR), and Transforming Growth Factor β Receptor (TGFβR) [version 2; peer review: 2 approved]

F1000Research
Fibroblasts are cells of mesenchymal origin that are found throughout the body. While these cells have several functions, their integral roles include maintaining tissue architecture through the production of key extracellular matrix components, and ...
Matthew B. Buechler, Maye F. Cheng, Faizah S. Abdullah   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Fibroblast growth factor 10 attenuates advanced liver fibrosis through hepatocyte fibroblast growth factor receptor 2 signalling

Clinical and Translational Medicine
Background Metabolic dysfunction–associated steatotic liver disease (MASLD) and advanced fibrotic stages are significant contributors to cirrhosis and liver‐related mortality, yet no therapies directly target fibrosis in the later stages of the disease ...
Xuanxin Yang, Qingqing Dong, Jiaying Ma, Yawei Yan, Shuangyan Peng, Qiqi Wu, Huan Wang, Tingting Zhang, Panyu Zhang, Zelong Jiang, Chao Lu, Le Li, Xinyi You, Yuandong Xu, Joshua Banda, Zhixiang Mu, Minghua Zheng, Xiaokun Li, Qi Hui, Bingjie Yu, Xiaojie Wang   +20 more
doaj   +1 more source

Topical fibroblast growth factor‐2 for treatment of chronic tympanic membrane perforations

Laryngoscope Investigative Otolaryngology, 2020
Objective To determine the efficacy of fibroblast growth factor‐2 (FGF‐2) in treating chronic nonhealing tympanic membrane (TM) perforations. Method Double‐blinded, randomized placebo controlled phase 2 clinical trial for patients with chronic TM ...
Felipe Santos, Edina Shu, Daniel J. Lee, David H. Jung, Alicia M. Quesnel, Konstantina M. Stankovic, Dunia E. Abdul‐Aziz, Camden P. Bay, Amy Quinkert, D. Bradley Welling   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source