Results 21 to 30 of about 316,930 (256)

Action of fibroblast growth factor-2 on the intervertebral disc [PDF]

Arthritis Research & Therapy, 2008
Abstract Introduction Fibroblast growth factor 2 (FGF2) is a growth factor that is immediately released after cartilage injury and plays a pivotal role in cartilage homeostasis. In human adult articular cartilage, FGF2 mediates anti-anabolic and potentially catabolic effects via the suppression of ...
Li, Xin, An, Howard S, Ellman, Michael, Phillips, Frank, Thonar, Eugene J, Park, Daniel K, Udayakumar, Ranjith K, Im, Hee-Jeong   +7 more
openaire   +2 more sources

Combined effects of melatonin and FGF-2 on mouse preosteoblast behavior within interconnected porous hydroxyapatite ceramics - in vitro analysis

Journal of Applied Oral Science, 2016
Objective Biocompatible materials such as interconnected porous hydroxyapatite ceramics (IP-CHA) loaded with osteogenic cells and bioactive agents are part of an evolving concept for overcoming craniofacial defects by use of artificial bone tissue ...
Mohammad Zeshaan RAHMAN, Hideo SHIGEISHI, Kazuki SASAKI, Akira OTA, Kouji OHTA, Masaaki TAKECHI   +5 more
doaj   +1 more source

Fibroblast growth factor-2 alters the nature of extinction [PDF]

Learning & Memory, 2011
These experiments examined the effects of the NMDA-receptor (NMDAr) antagonist MK801 on reacquisition and re-extinction of a conditioned fear that had been previously extinguished before injection of fibroblast growth factor-2 (FGF2) or vehicle. Recent findings have shown that relearning and re-extinction, unlike initial learning and extinction, do not
Bronwyn M, Graham, Rick, Richardson
openaire   +2 more sources

Prognostic role of fibroblast growth factor receptor 2 in human solid tumors: A systematic review and meta-analysis

Tumor Biology, 2017
In the past decades, the oncogenic role of fibroblast growth factor receptor 2 has been demonstrated in a number of cancer types. However, studies have reported contradictory findings concerning the correlation between fibroblast growth factor receptor 2
Gang Liu, Disheng Xiong, Rui Xiao, Zhengjie Huang   +3 more
doaj   +1 more source

A case of Pfeiffer syndrome with c833_834GC>TG (Cys278Leu) mutation in the gene [PDF]

Korean Journal of Pediatrics, 2010
Pfeiffer syndrome is a rare autosomal dominant disorder characterized by coronal craniosynostosis, brachycephaly, mid-facial hypoplasia, and broad and deviated thumbs and great toes.
Min Young Lee, Ga Won Jeon, Ji Mi Jung, Jong Beom Sin   +3 more
doaj   +1 more source

Fibroblast Growth Factor-2 Signaling in Neurogenesis and Neurodegeneration [PDF]

Journal of Neuroimmune Pharmacology, 2013
Fibroblast growth factor-2 (FGF2), also known as basic FGF, is a multi-functional growth factor. One of the 22-member FGF family, it signals through receptor tyrosine kinases encoding FGFR1-4. FGF2 activates FGFRs in cooperation with heparin or heparin sulfate proteoglycan to induce its pleiotropic effects in different tissues and organs, which include
Maya E, Woodbury, Tsuneya, Ikezu
openaire   +2 more sources

Fibroblast Growth Factor-2 (FGF-2) Expression in Pterygia Using Cell Spot Arrays

Vision, 2022
Fibroblast growth factor (FGF) is a main regulator of cell differentiation, cell migration and angiogenesis in normal and abnormal conjunctiva epithelia, but specific mechanisms of its aberrant expression are yet to be investigated. In the present study,
Stylianos Mastronikolis, Evangelos Tsiambas, Konstantinos Kagkelaris, Marina Pagkalou, Panagiotis Plotas, Sofianiki Mastronikoli, Dimitrios Roukas, Constantinos D. Georgakopoulos   +7 more
doaj   +1 more source

Fibroblast growth factor 2 control of vascular tone [PDF]

Nature Medicine, 1998
Vascular tone control is essential in blood pressure regulation, shock, ischemia-reperfusion, inflammation, vessel injury/repair, wound healing, temperature regulation, digestion, exercise physiology, and metabolism. Here we show that a well-known growth factor, FGF2, long thought to be involved in many developmental and homeostatic processes ...
M, Zhou, R L, Sutliff, R J, Paul, J N, Lorenz, J B, Hoying, C C, Haudenschild, M, Yin, J D, Coffin, L, Kong, E G, Kranias, W, Luo, G P, Boivin, J J, Duffy, S A, Pawlowski, T, Doetschman   +14 more
openaire   +2 more sources

Thrombin‐mediated impairment of fibroblast growth factor‐2 activity [PDF]

The FEBS Journal, 2009
Thrombin generation increases in several pathological conditions, including cancer, thromboembolism, diabetes and myeloproliferative syndromes. During tumor development, thrombin levels increase along with several other molecules, including cytokines and angiogenic factors.
Totta P, De Cristofaro R, GIAMPIETRI, Claudia, Aguzzi MS, Faraone D, Capogrossi MC, Facchiano A.   +6 more
openaire   +5 more sources

Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury

Neural Regeneration Research, 2022
The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited, especially in case of severe injury. This often leads to poor motor function and permanent disability.
Kamilla Faritovna Idrisova, Alina Kazymovna Zeinalova, Galina Andreevna Masgutova, Alexey Andreevich Bogov, Cinzia Allegrucci, Valeriia Yurievna Syromiatnikova, Ilnur Ildusovich Salafutdinov, Ekaterna Evgenievna Garanina, Dina Ivanovna Andreeva, Adilet Abdullaatovich Kadyrov, Albert Anatolevich Rizvanov, Ruslan Faridovich Masgutov   +11 more
doaj   +1 more source