Results 221 to 230 of about 665,368 (391)

Multiple structural elements determine ligand binding of fibroblast growth factor receptors. Evidence that both Ig domain 2 and 3 define receptor specificity.

, 1993
Yitzhak Zimmer, David Givol, Avner Yayon
openalex   +1 more source

Engineered 3D Kidney Glomerular Microtissues to Model Podocyte‐Centric Diseases for the Validation of New Drug Targets

Advanced Healthcare Materials, EarlyView.
The study introduces innovative 3D microtissues that replicate the glomerular filtration barrier of the kidney, offering a novel platform for understanding podocytopathies. These microtissues simulate the glomerulus's structure and dynamics, allowing for the modeling of podocyte injuries and drug testing.
Sara Buttό, Solange Vidal, Xi Rui Zeng, Martin Rausch, Immihan Ceren Yasa, Magali P. Ferro   +5 more
wiley   +1 more source

Fibroblast Growth Factor Receptor 2 (FGFR2), a New Gene Involved in the Genesis of Autism Spectrum Disorder. [PDF]

Neuromolecular Med, 2023
Nicotera AG, Amore G, Saia MC, Vinci M, Musumeci A, Chiavetta V, Federico C, Spoto G, Saccone S, Di Rosa G, Calì F.   +10 more
europepmc   +1 more source

Fibroblast growth factor receptors contain a conserved HAV region common to cadherins and influenza strain a hemagglutinins: A role in protein-protein interactions?

, 1992
Stephen W. Byers, Enrique Amaya, Sandra B. Munro, Orest W. Blaschuk   +3 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Prognostic Impact of Oncogenic Fibroblast Growth Factor Receptor Alterations in Patients With Advanced Solid Tumors in a Real-World Setting. [PDF]

Cancer Med
Demirdjian L, Triantos S, Standish K, Thomas S, Xia Q, Zhang J, Greshock J, Paone J, Sheridan P, Pant S, Massard C, Reardon DA, Loriot Y, Schuler M, Sweiti H.   +14 more
europepmc   +1 more source

Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma

Hepatology, 2014
Y. Arai, Y. Totoki, F. Hosoda, T. Shirota, Natsuko Hama, Hiromi Nakamura, H. Ojima, K. Furuta, K. Shimada, T. Okusaka, T. Kosuge, T. Shibata   +11 more
semanticscholar   +1 more source

Requirement for Anticoagulant Heparan Sulfate in the Fibroblast Growth Factor Receptor Complex [PDF]

, 1999
Wallace L. McKeehan, Xiaochong Wu, Mikio Kan   +2 more
openalex   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer. [PDF]

Mol Ther Nucleic Acids
Zlinska V, Feketova Z, Czyrek A, Chudzian J, Zivkovic ML, Ursachi VC, Dudeja P, Fafilek B, Rynes J, Rico-Llanos G, Koudelka A, Roy T, Biadun M, Raskova V, Svozilova K, Stroblova M, Krzyscik M, Hristova K, Krowarsch D, Foldynova-Trantirkova S, Zakrzewska M, Trantirek L, Krejci P.   +22 more
europepmc   +1 more source