Results 231 to 240 of about 10,197,473 (297)

High Dietary Phosphate Intake Induces Hypertension and Sympathetic Overactivation via Central Fibroblast Growth Factor Receptor Signaling. [PDF]

Circulation
Kim HK, Fukazawa A, Smith SA, Mizuno M, Rothermel BA, Fujikawa T, Galvan M, Gautron L, Pastor JV, Carroll IJ, Moe OW, Vongpatanasin W.   +11 more
europepmc   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source

Fibroblast growth factor receptor 2 (FGFR2) genetic polymorphisms contribute to fused roots in human molars. [PDF]

PLoS One
Meyfarth SRS, Baratto-Filho F, Locks MEN, Proff P, Zandoná GO, Fernandes TO, de França PHC, Kirschneck C, Antunes LS, Küchler EC.   +9 more
europepmc   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Cataracts Associated With Fibroblast Growth Factor Receptor Inhibitors for Cholangiocarcinoma.

JAMA Ophthalmol
Kassaye I, Alyafaie A, Zhang K, Lifton J, Gordan JD, Kelley RK, Yung M.   +6 more
europepmc   +1 more source

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer. [PDF]

Mol Ther Nucleic Acids
Zlinska V, Feketova Z, Czyrek A, Chudzian J, Zivkovic ML, Ursachi VC, Dudeja P, Fafilek B, Rynes J, Rico-Llanos G, Koudelka A, Roy T, Biadun M, Raskova V, Svozilova K, Stroblova M, Krzyscik M, Hristova K, Krowarsch D, Foldynova-Trantirkova S, Zakrzewska M, Trantirek L, Krejci P.   +22 more
europepmc   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source

Fibroblast Growth Factor Receptor (FGFR) Inhibitors for the Treatment of Cholangiocarcinoma: Key Therapeutic Developments and Knowledge Gaps. [PDF]

Drug Des Devel Ther
Erul E, Cifuentes-Canaval S, Santhosh A, Sokolović E, Della Mura M, Cazzato G, Kubilay Tolunay P, Rizzo A.   +7 more
europepmc   +1 more source

Fibroblast growth factor receptor signaling modulates cholesterol storage in a SOAT1-dependent manner to promote mammary tumor cell invasion. [PDF]

Breast Cancer Res
Tuokkola JE, Reese LE, Wang Y, O'Connor CH, VanTreeck JG, Rumahorbo AH, Schwertfeger KL.   +6 more
europepmc   +1 more source

miR-590-5p mediates mitochondrial respiration, proliferation, and apoptosis in thyroid carcinoma cells via fibroblast growth factor receptor substrate 2. [PDF]

Arch Endocrinol Metab
Wang P, Hou X, Sun W, Chen J, Cao Y, Cheng H.   +5 more
europepmc   +1 more source