Results 251 to 260 of about 607,524 (301)

Isoforms of Receptors of Fibroblast Growth Factors

Journal of Cellular Physiology, 2014
The breadth and scope of Fibroblast Growth Factor signaling is immense, with documentation of its role in almost every organism and system studied so far. FGF ligands signal through a family of four distinct tyrosine kinase receptors, the FGF receptors (FGFRs).
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Fibroblast Growth Factor Receptors

1997
Fibroblast growth factor (FGF) was discovered in the 1970s as an activity that stimulates the proliferation of 3T3 cells (1). Currently, FGFs comprise a family of nine structurally related proteins (FGF-1 to -9) (reviewed in 2–6). FGFs are expressed in specific spatial and temporal patterns and are involved in developmental processes, angiogenesis ...
David M. Ornitz, Gabriel Waksman
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Fibroblast Growth Factor 23 and Its Receptors

Therapeutic Apheresis and Dialysis, 2005
Abstract:  Fibroblast growth factor 23 (FGF23) is a circulating factor that plays critical roles in phosphate and vitamin D metabolism, as evidenced by the fact that FGF23 missense mutations cause autosomal dominant hypophosphatemic rickets (ADHR). Autosomal dominant hypophosphatemic rickets is characterized by hypophosphatemia with inappropriately ...
Xijie, Yu, Kenneth E, White
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Fibroblast Growth Factors and Their Receptors in Parathyroid Disease

World Journal of Surgery, 1998
AbstractFibroblast growth factors (FGFs) comprise a family of polypeptide growth factors implicated in the control of proliferation of glandular tissues. The aim of this study was to determine whether FGFs are produced in normal and abnormal parathyroid glands and if these tissues have the potential to respond to this growth factor family.
D, Lambert, C L, Eaton, B J, Harrison
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Immunohistochemical localization of growth factors fibroblast growth factor-1 and fibroblast growth factor-2 and receptors fibroblast growth factor receptor-2 and fibroblast growth factor receptor-3 in normal oral epithelium, epithelial dysplasias, and squamous cell carcinoma

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2002
Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been identified in a variety of carcinomas, but there are few studies concerning their presence in oral cancers. The objective of this study was to determine whether FGF-1, FGF-2, and high affinity receptors FGFR2 and FGFR3 are present in the pathogenesis of oral epithelial dysplasias ...
Candice, Wakulich, Linda, Jackson-Boeters, Tom D, Daley, George P, Wysocki   +3 more
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Immunclocalization of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptor-1 and Receptor-2 in Rat Cranial Sutures

Plastic and Reconstructive Surgery, 1998
Craniosynostosis is a common disorder with an unknown etiology. Recent genetic mapping studies have demonstrated a strong linkage between several familial craniosynostotic syndromes and mutations in fibroblast growth factor receptor 1 (FGF-R1) and 2 (FGF-R2).
B J, Mehrara, R J, Mackool, J G, McCarthy, G K, Gittes, M T, Longaker   +4 more
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Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas

Journal of Neuro-Oncology, 1994
Malignant astrocytomas are highly invasive, vascular neoplasms that comprise the majority of nervous system tumors in humans. A strong association has previously been made between malignancy in human astrocytic tumors and increased expression of certain fibroblast growth factor (FGF) family members, including basic and acidic FGF.
R S, Morrison, F, Yamaguchi, H, Saya, J M, Bruner, A M, Yahanda, L A, Donehower, M, Berger   +6 more
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Fibroblast Growth Factor and Epidermal Growth Factor Receptors in Ligament Healing

Clinical Orthopaedics and Related Research, 1997
Although recent in vivo studies indicate that basic fibroblast growth factor hastens the healing and strength of the medical collateral ligament after injury, in vitro studies with epidermal growth factor and basic fibroblast growth factor have shown increased fibroblast proliferation with the exogenous administration of these growth factors.
V, Panossian, S H, Liu, J M, Lane, G A, Finerman   +3 more
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Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation

Neuroscience, 2005
Basic fibroblast growth factor (bFGF) is an important mitogen and neurotrophic factor that binds and signals through the high-affinity receptor, fibroblast growth factor receptor 1 (FGFR1). However, only a limited amount of information is available concerning the molecular forms and anatomical distribution of fibroblast growth factors (FGFs) in the ...
C S, Weickert, D A, Kittell, R C, Saunders, M M, Herman, R A, Horlick, J E, Kleinman, T M, Hyde   +6 more
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Expression of basic fibroblast growth factor and fibroblast growth factor receptor in advanced gastric carcinoma

The Journal of Pathology, 1995
AbstractThe expression of basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor (FGFR) mRNA was examined in gastric carcinomas by immunohistochemistry and in situ hybridization, respectively. In the 20 advanced carcinomas examined, bFGF was found in 14 (70·0 per cent) and was confined to the tumour cells, whereas FGFR mRNA was ...
T, Ueki, T, Koji, S, Tamiya, P K, Nakane, M, Tsuneyoshi   +4 more
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