Results 241 to 250 of about 10,197,473 (297)

Prognostic Impact of Oncogenic Fibroblast Growth Factor Receptor Alterations in Patients With Advanced Solid Tumors in a Real-World Setting. [PDF]

open access: yesCancer Med
Demirdjian L   +14 more
europepmc   +1 more source

Retraction Note: Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

open access: yesArthritis Research & Therapy
Dongyao Yan   +6 more
doaj   +1 more source

Receptors for fibroblast growth factors

Immunology & Cell Biology, 1995
SummaryThe recent discovery of the involvement of heparan sulfate proteoglycans (HSPG) in the activation of fibroblast growth factor receptors (FGFR) has led to an intensification of study of this field. It appears that the HSPG act as low affinity receptors to which the fibroblast growth factors (FGF) must bind in order to successfully activate the ...
J C, Coutts, J T, Gallagher
openaire   +2 more sources

Fibroblast growth factors and their receptors

Biochemistry and Cell Biology, 1997
Fibroblast growth factors (FGFs) represent a group of polypeptide mitogens eliciting a wide variety of responses depending upon the target cell type. The knowledge of the cell surface receptors mediating the effects of FGFs has recently expanded remarkably.
Z, Galzie, A R, Kinsella, J A, Smith
openaire   +2 more sources

Fibroblast Growth Factors, Fibroblast Growth Factor Receptors, Diseases, and Drugs

Recent Patents on Cardiovascular Drug Discovery, 2006
Maintenance of endothelial cells (ECs), the building blocks of the vascular tree, is a presumed function of fibroblast growth factors (FGFs). In particular, the two prototypic members of FGF family, namely FGF1 and FGF2, due to their potent mitogenic and pro-migratory activities, have the ability to induce metabolic and phenotypic changes in ECs that ...
Gregory J, Chen, Reza, Forough
openaire   +2 more sources

Fibroblast Growth Factor Receptor Inhibitors

Current Pharmaceutical Design, 2012
Fibroblast growth factor receptors (FGFRs) play an important role in embryonic development, angiogenesis, wound healing, cell proliferation and differentiation. The fibroblast growth factor receptor (FGFR) isoforms have been under intense scrutiny for effective anticancer drug candidates.
Suneel B V S, Kumar   +4 more
openaire   +2 more sources

Promiscuity of fibroblast growth factor receptors

BioEssays, 1996
AbstractFibroblast growth factor receptors (FGFRs) have been implicated in many developmental and regenerative events, including axial organisation, mesodermal patterning, keratinocyte organisation and brain development. The consensus view that this reflects a role for one or other of the nine known members of the fibroblast growth factor family in ...
P J, Green, F S, Walsh, P, Doherty
openaire   +2 more sources

Home - About - Disclaimer - Privacy