Results 221 to 230 of about 607,524 (301)

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

The Prognostic Significance and Co-Expression of Fibroblast Growth Factor Receptor 2 and c-Met in Endometrial Cancer. [PDF]

Int J Womens Health
Gao H, Lu Q, Zhang J.
europepmc   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Sprouty2 Regulates Endocytosis and Degradation of Fibroblast Growth Factor Receptor 1 in Glioblastoma Cells. [PDF]

Cells
Hausott B, Pircher L, Kind M, Park JW, Claus P, Obexer P, Klimaschewski L.   +6 more
europepmc   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Efficacy of 2 different fibroblast growth factor receptor-inhibitors in a patient with extrahepatic cholangiocarcinoma harboring an FGFR2 mutation: a case report. [PDF]

Oncologist
Galli-Vareia I, Szturz P, Voutsadakis IA, Villard N, Tsoumakidou G, Fleury M, Herrera G, Fasquelle F, Godat S, Digklia A.   +9 more
europepmc   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands. [PDF]

Cytokine Growth Factor Rev
Krzyscik MA, Karl K, Dudeja P, Krejci P, Hristova K.   +4 more
europepmc   +1 more source

Fibroblast growth factor receptor risk signature predicts patient prognosis and immunotherapy resistance in colorectal cancer. [PDF]

Front Immunol
Li X, Pan Z, Luan T, Xiao Q, Li L, Wu Q, Yao G, Zhang X, Song D.   +8 more
europepmc   +1 more source

Fibroblast growth factor 23 and fibroblast growth factor receptor 4 promote cardiac metabolic remodeling in chronic kidney disease. [PDF]

Kidney Int
Fuchs MAA, Burke EJ, Latic N, Murray SL, Li H, Sparks MA, Abraham D, Zhang H, Rosenberg P, Saleem U, Hansen A, Miller SE, Ferreira D, Hänzelmann S, Hausmann F, Huber T, Erben RG, Fisher-Wellman K, Bursac N, Wolf M, Grabner A.   +20 more
europepmc   +1 more source