Results 101 to 110 of about 11,223 (224)
PLoS ONE, 2009 Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions. Recent genetic studies have shown that mutations within the gene encoding the SFTP filaggrin cause ichthyosis vulgaris and are major predisposing ...
Zhihong Wu +4 more
openaire +4 more sources
A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions
Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan +3 more
wiley +1 more source
Scientific ReportsThe function of the skin as a barrier against the environment depends on the differentiation of epidermal keratinocytes into highly resilient corneocytes that form the outermost skin layer.
Julia Steinbinder +3 more
doaj +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
The Journal of biological chemistry, 1996 Peptidylarginine deiminases, which are commonly found in mammalian cells, catalyze the deimination of protein-bound arginine residues to citrullines. However, very little is known about their substrate requirements and the significance or consequences of this postsynthetic modification.
Edit Tarcsa +5 more
openaire +3 more sources
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Food Frontiers, Volume 7, Issue 2, March 2026.Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
Pharmaceutical Biology, 2019 Context: Citrus unshiu Markovich (Rutaceae) peel is known to contain high concentrations of flavonoids and exerts pharmacological effects on antioxidant, anti-inflammation, allergies, diabetes and viral infections.
Chulwon Kim +8 more
doaj +1 more source
Sleep Research, Volume 3, Issue 1, Page 33-46, March 2026.Abstract Background Sleep deprivation leads to changes in circadian rhythm, causing skin problems and aging. Whether acute sleep deprivation can be normalized after 14 days of natural skin metabolism is an important indicator for guiding treatment of sleep‐related skin physiological changes and mechanisms.
Qianxin Zhu +7 more
wiley +1 more source
Recent positive selection in genes of the mammalian epidermal differentiation complex locus [PDF]
, 2017 The epidermal differentiation complex (EDC) is the most rapidly evolving locus in the human genome compared to that of the chimpanzee. Yet the EDC genes that are undergoing positive selection across mammals and in humans are not known.
Goodwin, Zane A +1 more
core +2 more sources
The epidthelial sodium channel ENaC and its regulators in the epidermal permeability barrier function [PDF]
, 2010 The highly amiloride-sensitive epithelial sodium channel ENaC is well known to be involved in controlling whole body sodium homeostasis and lung liquid clearance. ENaC expression has also been detected in the skin of amphibians and mammals.
Charles, R-P. +2 more
core +1 more source