Results 61 to 70 of about 5,542 (153)

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Immunodominant Domains Present on theBordetella pertussisVaccine Component Filamentous Hemagglutinin [PDF]

The Journal of Infectious Diseases, 1997
To identify immunologically important domains on filamentous hemagglutinin (FHA), a Bordetella pertussis protein included in new acellular pertussis vaccines (ACPVs), a series of monoclonal antibodies, sera from infants vaccinated with ACPVs or whole cell pertussis vaccine (WCPV), and sera from patients with pertussis were analyzed by immunoblots ...
E, Leininger, S, Bowen, G, Renauld-Mongénie, J H, Rouse, F D, Menozzi, C, Locht, I, Heron, M J, Brennan   +7 more
openaire   +2 more sources

To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility

Molecular Microbiology, EarlyView.
Motility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses. This process is controlled by associated mechanisms such as post‐translational modifications and second messenger signalling that stabilise non‐motile ...
Fatemeh Mohaghegh, Jacob Scadden, Matthew A. B. Baker   +2 more
wiley   +1 more source

Bordetella pertussis binds the human complement regulator C4BP: role of filamentous hemagglutinin [PDF]

Infection and Immunity, 1997
C4BP (C4b-binding protein) is a high-molecular-weight plasma protein that inhibits the classical pathway of complement activation. Recent experiments have demonstrated that C4BP binds to many strains of the gram-positive bacterium Streptococcus pyogenes, a major respiratory tract pathogen. Binding to S.
Berggard, K, Johnsson, E, Mooi, FR, Lindahl, G   +3 more
openaire   +3 more sources

Morphology-dependent entry kinetics and spread of influenza A virus

The EMBO Journal
Influenza A viruses (IAV) display a broad variety of morphologies ranging from spherical to long filamentous virus particles. These diverse phenotypes are believed to allow the virus to overcome various immunological and pulmonary barriers during entry ...
Sarah Peterl, Carmen M Lahr, Carl N Schneider, Janis Meyer, Xenia Podlipensky, Vera Lechner, Maria Villiou, Larissa Eis, Steffen Klein, Charlotta Funaya, Elisabetta Ada Cavalcanti-Adam, Frederik Graw, Christine Selhuber-Unkel, Karl Rohr, Petr Chlanda   +14 more
doaj   +1 more source

An FtsH protease is recruited to the mitochondrion of Plasmodium falciparum. [PDF]

PLoS ONE, 2013
The two organelles, apicoplast and mitochondrion, of the malaria parasite Plasmodium falciparum have unique morphology in liver and blood stages; they undergo complex branching and looping prior to division and segregation into daughter merozoites ...
Aiman Tanveer, Stacey M Allen, Katherine E Jackson, Manish Charan, Stuart A Ralph, Saman Habib   +5 more
doaj   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Mucosal immunization with filamentous hemagglutinin protects against Bordetella pertussis respiratory infection [PDF]

Infection and Immunity, 1992
Mucosal immunization of mice with purified Bordetella pertussis filamentous hemagglutinin (FHA), by either the respiratory or the gut route, was found to protect against B. pertussis infection of the trachea and lungs. Intranasal immunization of BALB/c and (C57BL/6 x C3H/HeN)F1 adult female mice with FHA prior to B. pertussis aerosol challenge resulted
R D, Shahin, D F, Amsbaugh, M F, Leef
openaire   +2 more sources

Genotypic Characterization of Bordetella bronchiseptica Strains Isolated from Stray and Pet Dogs [PDF]

Pakistan Veterinary Journal, 2016
Bordetella bronchiseptica (B. bronchiseptica) is the most important pathogen associated with kennel cough in dogs. The presence of B. bronchiseptica in pet dogs and shelter dogs with clinical respiratory disease was investigated in present study.
Zafer Sayin1*, Asli Sakmanoglu1, Osman Erganis1, Uckun Sait Ucan1, Hasan Huseyin Hadimli1, Zeki Aras2, Gokcenur Sanioglu2 and Alp Aslan Coskun3
doaj  

Role of Evolutionary Selection Acting on Vaccine Antigens in the Re-Emergence of Bordetella Pertussis

Diseases, 2019
Pertussis (“whooping cough”) is a re-emerging disease with increasing incidence among fully vaccinated individuals. We explored the genetic diversity of five Bordetella pertussis proteins used to generate the subunit vaccine across ancestral and newly ...
Haley Etskovitz, Nicole Anastasio, Evangeline Green, Meghan May   +3 more
doaj   +1 more source