Results 41 to 50 of about 10,264 (194)

Robust Humoral and Cellular Immune Responses to Pertussis in Adults After a First Acellular Booster Vaccination [PDF]

, 2018
IntroductionTo reduce the pertussis disease burden, nowadays several countries recommend acellular pertussis (aP) booster vaccinations for adults.
Anne-Marie Buisman, Axel Bonacic Marinovic, Debbie M. van Rooijen, Elisabeth A. M. Sanders, Elisabeth A. M. Sanders, Guy A. M. Berbers, Marjan J. M. Bogaard, Mary-Lène de Zeeuw-Brouwer, Pieter G. M. van Gageldonk, Saskia van der Lee, Saskia van der Lee   +10 more
core   +9 more sources

Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen burkholderia pseudomallei K96243 [PDF]

, 2010
Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions, including South East Asia and Northern Australia, where it causes melioidosis, a serious disease ...
Bentley, Stephen D., Dowling, Andrea J., ffrench-Constant, Richard H., Holden, Matthew T. G., Quail, Michael A., Reger, Julia, Titball, Richard W., Waterfield, Nicholas R., Wilkinson, Paul A.   +8 more
core   +12 more sources

Immunogenicity of a new enhanced tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine against Bordetella pertussis in a murine model

BMC Immunology, 2021
Background The necessity of the tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine in adolescence and adults has been emphasized since the resurgence of small-scale pertussis in Korea and worldwide due to the waning effect of the vaccine ...
Kyu Ri Kang, Dong Ho Huh, Ji Ahn Kim, Jin Han Kang   +3 more
doaj   +1 more source

Filamentous hemagglutinin adhesin FhaB limits i A baumannii i biofilm formation

Frontiers in Bioscience, 2017
Increased resistance and survival, as well as immune evasion, play a significant role in the pathogenicity of Acinetobacter baumannii. Here, we report on the adhesion of the bacterium to epithelial cells and formation of biofilm on abiotic surfaces. We identificed autotransporter (AT) genes that encode homologues (Fha-like) of the two-partner secretion
Shakiba, Darwish Alipour Astaneh, Iraj, Rasooli, Seyed Latif, Mousavi Gargari   +2 more
openaire   +2 more sources

Characterization of the Filamentous Hemagglutinin-Like Protein FhaS in Bordetella bronchiseptica [PDF]

Infection and Immunity, 2005
ABSTRACT Filamentous hemagglutinin (FHA) is a large (>200 kDa), rod-shaped protein expressed by bordetellae that is both surface-associated and secreted. FHA mediates bacterial adherence to epithelial cells and macrophages in vitro and is absolutely required for tracheal colonization in vivo. The recently sequenced
Steven M, Julio, Peggy A, Cotter
openaire   +2 more sources

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

Computational and Structural Biotechnology Journal, 2022
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim, John Tracey, Manuel Becerra Flores, Kanita Chaudhry, Rafae Nasim, Abraham Correa-Medina, Leslie Knipling, Qing Chen, Scott Stibitz, Lisa M.M. Jenkins, Kyung Moon, Tim Cardozo, Deborah M. Hinton   +12 more
doaj   +1 more source

Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection [PDF]

, 2011
Copyright © 2012, American Society for Microbiology. All Rights ReservedThe influenza A virus M2 ion channel protein has the longest cytoplasmic tail (CT) among the three viral envelope proteins and is well conserved between different viral strains.
B. Nal, Barman, Barman, Bruce, Carlton, Chen, Chen, Chen, Cheung, Ciampor, Compans, Creutz, Cubells, Eierhoff, Enrich, F. Kien, Formstecher, Fromont-Racine, Gannagé, Gerke, Goswami, Grantham, Guan, Gujuluva, H. Ma, Harris, Hartshorn, Henkel, Hoffmann, Holsinger, Honda, Hui, Ichinohe, Iwatsuki-Horimoto, K. S. Tse, L. L. M. Poon, Lakadamyali, Lamb, Lamb, Lee, Li, Liu, M. Maniere, McCown, McCown, Monastyrskaya, N. Lagarde, Nayak, Nefkens, Noton, Palese, Pinto, Pinto, Pinto, Pleschka, Rossman, Rossman, Rossman, Scheiffele, Simpson-Holley, Smythe, Sun, Thaa, Thomas, Ueda, Vila de Muga, Wang, Wang, Welsch, Y. Zhang   +69 more
core   +2 more sources

Serological response to filamentous hemagglutinin and lymphocytosis-promoting toxin of Bordetella pertussis [PDF]

Infection and Immunity, 1983
Serum antibody responses to the filamentous hemagglutinin and the lymphocytosis-promoting toxin of Bordetella pertussis after vaccination with diphtheria and tetanus toxoids and pertussis vaccine, adsorbed, were assayed by using the enzyme-linked immunosorbent assay.
D G, Burstyn, L J, Baraff, M S, Peppler, R D, Leake, J, St Geme, C R, Manclark   +5 more
openaire   +2 more sources

Identification of a carbohydrate recognition domain in filamentous hemagglutinin from Bordetella pertussis [PDF]

Infection and Immunity, 1993
The adherence of Bordetella pertussis to ciliated cells and macrophages is critical to colonization and infection of the respiratory tract. Adherence to both types of cells involves the recognition of eukaryotic carbohydrates by the bacterial adhesin filamentous hemagglutinin (Fha).
S M, Prasad, Y, Yin, E, Rodzinski, E I, Tuomanen, H R, Masure   +4 more
openaire   +2 more sources

Genome dynamics of Bartonella grahamii in micro-populations of woodland rodents [PDF]

, 2010
Background Rodents represent a high-risk reservoir for the emergence of new human pathogens. The recent completion of the 2.3 Mb genome of Bartonella grahamii, one of the most prevalent blood-borne bacteria in wild rodents, revealed a higher abundance of
Eva C Berglund, Christian Ehrenborg, Olga Vinnere Pettersson, Fredrik Granberg, Kristina Näslund, Martin Holmberg, Siv GE Andersson   +6 more
core   +2 more sources