Cloning of the filamentous hemagglutinin of Bordetella pertussis and its expression in Escherichia coli [PDF]
Bordetella pertussis UT25 DNA was cloned into the kanamycin resistance gene of cosmid pCP13 to construct a genomic library in Escherichia coli LE392. One clone containing plasmid pDB441 expressed the filamentous hemagglutinin (FHA) as identified by protein immunoblots with the use of rabbit anti-B.
D R, Brown, C D, Parker
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Contribution of Bordetella bronchiseptica filamentous hemagglutinin and pertactin to respiratory disease in swine. [PDF]
ABSTRACTBordetella bronchisepticais pervasive in swine populations and plays multiple roles in respiratory disease. Most studies addressing virulence factors ofB. bronchisepticaare based on isolates derived from hosts other than pigs. Two well-studied virulence factors implicated in the adhesion process are filamentous hemagglutinin (FHA) and pertactin
Nicholson TL, Brockmeier SL, Loving CL.
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Heparin-inhibitable lectin activity of the filamentous hemagglutinin adhesin of Bordetella pertussis [PDF]
Bordetella pertussis, the etiologic agent of whooping cough, produces an outer membrane-associated filamentous hemagglutinin (FHA) which is the major adhesin of this organism. FHA exhibits a lectin-like activity for heparin and dextran sulfate. By using in vitro adherence assays to cultured epithelial cells, the attachment of B.
F D, Menozzi +7 more
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Influenza A virus surface proteins are organized to help penetrate host mucus
Influenza A virus (IAV) enters cells by binding to sialic acid on the cell surface. To accomplish this while avoiding immobilization by sialic acid in host mucus, viruses rely on a balance between the receptor-binding protein hemagglutinin (HA) and the ...
Michael D Vahey, Daniel A Fletcher
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New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates
Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of ...
Valérie Bouchez +4 more
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A filamentous hemagglutinin-like protein of Xanthomonas axonopodis pv. citri, the phytopathogen responsible for citrus canker, is involved in bacterial virulence. [PDF]
Xanthomonas axonopodis pv. citri, the phytopathogen responsible for citrus canker has a number of protein secretion systems and among them, at least one type V protein secretion system belonging to the two-partner secretion pathway. This system is mainly
Natalia Gottig +4 more
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The H9N2 subtype of influenza A virus circulates frequently among poultry in Asian and North African countries causing economic loss in the poultry sector. The antigenic variations of the H9N2 virus were at the origin of its genetic evolution through the
Marwa Arbi +7 more
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Adhesion and host cell modulation: critical pathogenicity determinants of
Bartonella henselae, the agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis, contains to date two groups of described pathogenicity factors: adhesins and type IV secretion systems.
Kempf Volkhard AJ, Franz Bettina
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Twenty-two atypical enteroaggregative Escherichia coli isolates from a previous epidemiological study harboring EAEC virulence genes were examined for their adhesion properties.
Mariane V. Monfardini +5 more
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Filamentous hemagglutinin adhesin FhaB limits i A baumannii i biofilm formation
Increased resistance and survival, as well as immune evasion, play a significant role in the pathogenicity of Acinetobacter baumannii. Here, we report on the adhesion of the bacterium to epithelial cells and formation of biofilm on abiotic surfaces. We identificed autotransporter (AT) genes that encode homologues (Fha-like) of the two-partner secretion
Shakiba, Darwish Alipour Astaneh +2 more
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