Results 41 to 50 of about 5,812 (161)

Heparin-inhibitable lectin activity of the filamentous hemagglutinin adhesin of Bordetella pertussis [PDF]

Infection and Immunity, 1994
Bordetella pertussis, the etiologic agent of whooping cough, produces an outer membrane-associated filamentous hemagglutinin (FHA) which is the major adhesin of this organism. FHA exhibits a lectin-like activity for heparin and dextran sulfate. By using in vitro adherence assays to cultured epithelial cells, the attachment of B.
F D, Menozzi, R, Mutombo, G, Renauld, C, Gantiez, J H, Hannah, E, Leininger, M J, Brennan, C, Locht   +7 more
openaire   +2 more sources

New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates

Vaccines, 2015
Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of ...
Valérie Bouchez, Nicolas Hegerle, Francesco Strati, Elisabeth Njamkepo, Nicole Guiso   +4 more
doaj   +1 more source

Contribution of Bordetella bronchiseptica filamentous hemagglutinin and pertactin to respiratory disease in swine. [PDF]

Infect Immun, 2009
ABSTRACTBordetella bronchisepticais pervasive in swine populations and plays multiple roles in respiratory disease. Most studies addressing virulence factors ofB. bronchisepticaare based on isolates derived from hosts other than pigs. Two well-studied virulence factors implicated in the adhesion process are filamentous hemagglutinin (FHA) and pertactin
Nicholson TL, Brockmeier SL, Loving CL.
europepmc   +4 more sources

A filamentous hemagglutinin-like protein of Xanthomonas axonopodis pv. citri, the phytopathogen responsible for citrus canker, is involved in bacterial virulence. [PDF]

PLoS ONE, 2009
Xanthomonas axonopodis pv. citri, the phytopathogen responsible for citrus canker has a number of protein secretion systems and among them, at least one type V protein secretion system belonging to the two-partner secretion pathway. This system is mainly
Natalia Gottig, Betiana S Garavaglia, Cecilia G Garofalo, Elena G Orellano, Jorgelina Ottado   +4 more
doaj   +1 more source

Inhibition of avian influenza virus H9N2 infection by antiviral hexapeptides that target viral attachment to epithelial cells

Virus Research, 2022
The H9N2 subtype of influenza A virus circulates frequently among poultry in Asian and North African countries causing economic loss in the poultry sector. The antigenic variations of the H9N2 virus were at the origin of its genetic evolution through the
Marwa Arbi, Imen Larbi, Jihen Nsiri, Imen El Behi, Ahmed Rejeb, Khaled Miled, Adeljelil Ghram, Mehdi Houimel   +7 more
doaj   +1 more source

Adhesion and host cell modulation: critical pathogenicity determinants of Bartonella henselae

Parasites & Vectors, 2011
Bartonella henselae, the agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis, contains to date two groups of described pathogenicity factors: adhesins and type IV secretion systems.
Kempf Volkhard AJ, Franz Bettina
doaj   +1 more source

Transposon mutagenesis of atypical enteroaggregative Escherichia coli reveals a hemagglutinin-associated protein that mediates cell adhesion and contributes to the Galleria mellonella virulence

Frontiers in Cellular and Infection Microbiology, 2023
Twenty-two atypical enteroaggregative Escherichia coli isolates from a previous epidemiological study harboring EAEC virulence genes were examined for their adhesion properties.
Mariane V. Monfardini, Renata T. Souza, Thais C. G. Rojas, Caroline G. Guerrieri, Cristina Orikaza, Isabel C. A. Scaletsky   +5 more
doaj   +1 more source

Filamentous hemagglutinin adhesin FhaB limits i A baumannii i biofilm formation

Frontiers in Bioscience, 2017
Increased resistance and survival, as well as immune evasion, play a significant role in the pathogenicity of Acinetobacter baumannii. Here, we report on the adhesion of the bacterium to epithelial cells and formation of biofilm on abiotic surfaces. We identificed autotransporter (AT) genes that encode homologues (Fha-like) of the two-partner secretion
Shakiba, Darwish Alipour Astaneh, Iraj, Rasooli, Seyed Latif, Mousavi Gargari   +2 more
openaire   +2 more sources

Multiplex Point-of-Care Tests for the Determination of Antibodies after Acellular Pertussis Vaccination

Diagnostics, 2020
Most of the current serological diagnosis of pertussis is based on pertussis toxin (PT) IgG antibodies and does not differentiate between vaccination and infection-induced antibodies. PT is included in all of acellular pertussis vaccines available in the
Aapo Knuutila, Carita Rautanen, Jussi Mertsola, Qiushui He   +3 more
doaj   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source