Results 31 to 40 of about 5,542 (153)

Serological response to filamentous hemagglutinin and lymphocytosis-promoting toxin of Bordetella pertussis [PDF]

Infection and Immunity, 1983
Serum antibody responses to the filamentous hemagglutinin and the lymphocytosis-promoting toxin of Bordetella pertussis after vaccination with diphtheria and tetanus toxoids and pertussis vaccine, adsorbed, were assayed by using the enzyme-linked immunosorbent assay.
D G, Burstyn, L J, Baraff, M S, Peppler, R D, Leake, J, St Geme, C R, Manclark   +5 more
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Characterization of the Filamentous Hemagglutinin-Like Protein FhaS in Bordetella bronchiseptica [PDF]

Infection and Immunity, 2005
ABSTRACT Filamentous hemagglutinin (FHA) is a large (>200 kDa), rod-shaped protein expressed by bordetellae that is both surface-associated and secreted. FHA mediates bacterial adherence to epithelial cells and macrophages in vitro and is absolutely required for tracheal colonization in vivo. The recently sequenced
Steven M, Julio, Peggy A, Cotter
openaire   +2 more sources

Peroxin 14 tags peroxisomes and interacts with Nbr1 for pexophagy in the filamentous insect pathogenic fungus Beauveria bassiana

Autophagy Reports, 2023
Pexophagy is a main pathway for selective degradation of peroxisomes. However, the molecular mechanisms underlying pexophagy remain fragmented in the filamentous fungi.
Hai-Yan Lin, Jia-Hui Lei, Jin-Li Ding, Yue-Jin Peng, Hao Zhang, Ming-Guang Feng, Sheng-Hua Ying   +6 more
doaj   +1 more source

Identification of a carbohydrate recognition domain in filamentous hemagglutinin from Bordetella pertussis [PDF]

Infection and Immunity, 1993
The adherence of Bordetella pertussis to ciliated cells and macrophages is critical to colonization and infection of the respiratory tract. Adherence to both types of cells involves the recognition of eukaryotic carbohydrates by the bacterial adhesin filamentous hemagglutinin (Fha).
S M, Prasad, Y, Yin, E, Rodzinski, E I, Tuomanen, H R, Masure   +4 more
openaire   +2 more sources

Acellular Pertussis Vaccine Components: Today and Tomorrow

Vaccines, 2020
Pertussis is a highly communicable acute respiratory infection caused by Bordetella pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks occur cyclically worldwide and effective vaccination strategies are needed
Kalyan K. Dewan, Bodo Linz, Susan E. DeRocco, Eric T. Harvill   +3 more
doaj   +1 more source

Proinflammatory and Proapoptotic Activities Associated withBordetella pertussisFilamentous Hemagglutinin [PDF]

Infection and Immunity, 2001
ABSTRACTFilamentous hemagglutinin (FHA) is a dominant cell surface-associatedBordetella pertussisadhesin. Recognition that this protein is secreted in significant amounts and that bacterial adhesins may have other actvities, prompted an assessment of FHA effects on human macrophages.
T, Abramson, H, Kedem, D A, Relman
openaire   +2 more sources

Immunogenicity of a new enhanced tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine against Bordetella pertussis in a murine model

BMC Immunology, 2021
Background The necessity of the tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine in adolescence and adults has been emphasized since the resurgence of small-scale pertussis in Korea and worldwide due to the waning effect of the vaccine ...
Kyu Ri Kang, Dong Ho Huh, Ji Ahn Kim, Jin Han Kang   +3 more
doaj   +1 more source

Identification of immunodominant epitopes in the filamentous hemagglutinin ofBordetella pertussis [PDF]

FEMS Immunology & Medical Microbiology, 1999
The filamentous hemagglutinin (FHA) of Bordetella pertussis is a principal adhesin, which plays a key role in the colonization of the upper respiratory tract. FHA is also a protective antigen, which has been incorporated in the new generation of acellular vaccines against whooping cough. The protein is synthesized as a large 367-kDa precursor, which is
openaire   +3 more sources

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

Computational and Structural Biotechnology Journal, 2022
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim, John Tracey, Manuel Becerra Flores, Kanita Chaudhry, Rafae Nasim, Abraham Correa-Medina, Leslie Knipling, Qing Chen, Scott Stibitz, Lisa M.M. Jenkins, Kyung Moon, Tim Cardozo, Deborah M. Hinton   +12 more
doaj   +1 more source

Mutant of Bordetella pertussis which lacks ability to produce filamentous hemagglutinin [PDF]

Infection and Immunity, 1982
Mutant cultures that lacked the ability to produce filamentous hemagglutinin were obtained by UV irradiation of Bordetella pertussis strain 18-323. Various biological activities of these mutants were compared with those of the parent culture. It was found that the leukocytosis-promoting, histamine-sensitizing, and mouse-protecting activities of the ...
M, Watanabe, Y, Nakase
openaire   +2 more sources