Results 31 to 40 of about 10,264 (194)
Surface-associated filamentous hemagglutinin induces autoagglutination of Bordetella pertussis [PDF]
Filamentous hemagglutinin (FHA) is a major adhesin produced by Bordetella pertussis, the etiologic agent of whooping cough. FHA has been shown to be surface associated but is also secreted by virulent bacteria. Microscopic observations of lungs of mice infected with B. pertussis showed that the bacteria grow as clusters within the alveolar lumen.
F D, Menozzi +4 more
openaire +2 more sources
Proinflammatory and Proapoptotic Activities Associated withBordetella pertussisFilamentous Hemagglutinin [PDF]
ABSTRACTFilamentous hemagglutinin (FHA) is a dominant cell surface-associatedBordetella pertussisadhesin. Recognition that this protein is secreted in significant amounts and that bacterial adhesins may have other actvities, prompted an assessment of FHA effects on human macrophages.
T, Abramson, H, Kedem, D A, Relman
openaire +2 more sources
Background/Purpose: Although assessing the immunogenicity and protective efficacy of acellular pertussis (aP) vaccines via murine model studies faces limitations, preliminary assessments have been achieved by evaluating respiratory challenge and humoral ...
Dong Ho Huh +7 more
doaj +1 more source
Mutant of Bordetella pertussis which lacks ability to produce filamentous hemagglutinin [PDF]
Mutant cultures that lacked the ability to produce filamentous hemagglutinin were obtained by UV irradiation of Bordetella pertussis strain 18-323. Various biological activities of these mutants were compared with those of the parent culture. It was found that the leukocytosis-promoting, histamine-sensitizing, and mouse-protecting activities of the ...
M, Watanabe, Y, Nakase
openaire +2 more sources
Influenza virus morphogenesis and budding. [PDF]
Influenza viruses are enveloped, negative stranded, segmented RNA viruses belonging to Orthomyxoviridae family. Each virion consists of three major sub-viral components, namely (i) a viral envelope decorated with three transmembrane proteins ...
Balogun, Rilwan A +4 more
core +1 more source
Mucosal immunization with filamentous hemagglutinin protects against Bordetella pertussis respiratory infection [PDF]
Mucosal immunization of mice with purified Bordetella pertussis filamentous hemagglutinin (FHA), by either the respiratory or the gut route, was found to protect against B. pertussis infection of the trachea and lungs. Intranasal immunization of BALB/c and (C57BL/6 x C3H/HeN)F1 adult female mice with FHA prior to B. pertussis aerosol challenge resulted
R D, Shahin, D F, Amsbaugh, M F, Leef
openaire +2 more sources
Pexophagy is a main pathway for selective degradation of peroxisomes. However, the molecular mechanisms underlying pexophagy remain fragmented in the filamentous fungi.
Hai-Yan Lin +6 more
doaj +1 more source
Alterations of membrane curvature during influenza virus budding [PDF]
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
core +1 more source
Pasteurella multocida, a Gram-negative nonmotile coccobacillus, is the causative agent of fowl cholera, bovine hemorrhagic septicemia, enzoonotic pneumonia and swine atropic rhinitis.
Dong-chun GUO +9 more
doaj +1 more source
Acellular Pertussis Vaccine Components: Today and Tomorrow
Pertussis is a highly communicable acute respiratory infection caused by Bordetella pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks occur cyclically worldwide and effective vaccination strategies are needed
Kalyan K. Dewan +3 more
doaj +1 more source

