Results 41 to 50 of about 4,457 (158)

Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin

open access: yesCell Reports, 2023
Summary: Ebola virus (EBOV) and Bundibugyo virus (BDBV) belong to the family Filoviridae and cause a severe disease in humans. We previously isolated a large panel of monoclonal antibodies from B cells of human survivors from the 2007 Uganda BDBV ...
Rodrigo I. Santos   +8 more
doaj   +1 more source

Potential Vaccines and Post-Exposure Treatments for Filovirus Infections

open access: yesViruses, 2012
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger   +6 more
doaj   +1 more source

Ebola virus: A global public health menace: A narrative review

open access: yesJournal of Family Medicine and Primary Care, 2019
Ebola virus disease (EVD), a fatal viral hemorrhagic illness, is due to infection with the Ebola virus of the Filoviridae family. The disease has evolved as a global public health menace due to a large immigrant population.
Shamimul Hasan   +3 more
doaj   +1 more source

Ebola hemorrhagic fever outbreaks: strategies for effective epidemic management, containment and control

open access: yesBrazilian Journal of Infectious Diseases, 2015
Ebola hemorrhagic fever, caused by the highly virulent RNA virus of the filoviridae family, has become one of the world's most feared pathogens. The virus induces acute fever and death, often associated with hemorrhagic symptoms in up to 90% of infected ...
Gerald Amandu Matua   +2 more
doaj   +1 more source

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis

open access: yesПроблемы особо опасных инфекций, 2018
Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova   +2 more
doaj   +1 more source

Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015

open access: yesEmerging Infectious Diseases, 2017
Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%–99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism.
Xing-Lou Yang   +13 more
doaj   +1 more source

CryoEM structure of the Nipah virus nucleocapsid assembly.

open access: yesPLoS Pathogens, 2021
Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral immunogen.
De-Sheng Ker   +3 more
doaj   +1 more source

Ebolavirus and Haemorrhagic Syndrome

open access: yesSultan Qaboos University Medical Journal, 2015
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in
Gerald A. Matua   +2 more
doaj  

Ebola virus disease: past, present and future

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak   +4 more
doaj   +1 more source

PAirwise Sequence Comparison (PASC) and Its Application in the Classification of Filoviruses

open access: yesViruses, 2012
PAirwise Sequence Comparison (PASC) is a tool that uses genome sequence similarity to help with virus classification. The PASC tool at NCBI uses two methods: local alignment based on BLAST and global alignment based on Needleman-Wunsch algorithm.
Tatiana Tatusova   +2 more
doaj   +1 more source

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