Results 41 to 50 of about 3,948 (186)

Luminescent reporter cells enable the identification of broad‐spectrum antivirals against emerging viruses

open access: yesJournal of Medical Virology, Volume 95, Issue 11, November 2023., 2023
Abstract The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and hemorrhagic diseases, respectively. The production of infectious particles of both viruses and virus spread in tissues requires cleavage of surface glycoproteins (GPs) by host proprotein convertases (PCs).
Karin Löw   +10 more
wiley   +1 more source

The West African ebola virus disease epidemic 2014–2015: A commissioned review

open access: yesNigerian Postgraduate Medical Journal, 2016
The first epidemic of Ebola haemorrhagic disease in West Africa is the largest and longest Ebola epidemic till date, where the outbreak notably involved three countries with distant spread to other countries.
S A Omilabu   +3 more
doaj   +1 more source

An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells.

open access: yesPLoS ONE, 2021
Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved.
Yingyun Cai   +5 more
doaj   +1 more source

Communicating the risks of handling bats: analysing approaches used by Australian stakeholders in the context of Australian bat lyssavirus

open access: yesAustralian Veterinary Journal, Volume 101, Issue 11, Page 430-439, November 2023., 2023
Australian bat lyssavirus (ABLV) is a member of the Lyssavirus genus of the Rhabdoviridae family and is found in Australian bat species. It is of public health concern because of the rabies‐like syndrome it causes in humans, resulting in government health and wildlife agencies using varied communication approaches to inform targeted audiences about ...
BP Liang   +3 more
wiley   +1 more source

The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]

open access: yesPLoS ONE, 2016
Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann   +4 more
doaj   +1 more source

The mortality, modes of infection, diagnostic tests, and treatments of Marburg virus disease: A systematic review

open access: yesHealth Science Reports, Volume 6, Issue 9, September 2023., 2023
Abstract Background and Aims Marburg virus (MARV) has regularly affected people since 1967 causing multiple outbreaks. There are presently no authorized therapies for the fatal Marburg virus disease (MVD), which poses an imminent risk to global public health.
Deekshitha Alla   +10 more
wiley   +1 more source

Exploring the human-animal interface of Ebola virus disease outbreaks

open access: yesMathematical Biosciences and Engineering, 2019
Whereas the prevention and treatment of Ebola virus disease (EVD) have been well studied after the 2013–16 outbreak in West Africa, the emergence of human outbreaks and their mechanisms have yet to be explored in detail.
Luis Ponce   +2 more
doaj   +1 more source

Highly Effective xMAP Multiplex Assay for the Detection and Identification of Hemorrhagic Fever Agents, Including Ebola Virus

open access: yesПроблемы особо опасных инфекций, 2015
Developed has been the oligonucleotide liquid biochip based on xMAP technology, designed for the laboratory detection of particularly dangerous viral pathogens such as Ebola and Marburg filoviruses, and Machupo , Junin, and Lassa arenaviruses.
V. A. Ternovoy   +5 more
doaj   +1 more source

Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria

open access: yesJournal of Epidemiology and Global Health, 2018
Ebola viruses (family: Filoviridae) are the cause of Ebola virus disease (EVD), a highly fatal illness characterised by haemorrhagic fever syndrome in both humans and non-human primates (NHPs).
B.N. Ogunro   +5 more
doaj   +1 more source

Morphologic Differentiation of Viruses beyond the Family Level

open access: yesViruses, 2014
Electron microscopy has been instrumental in the identification of viruses by being able to characterize a virus to the family level. There are a few cases where morphologic or morphogenesis factors can be used to differentiate further, to the genus ...
Cynthia S. Goldsmith
doaj   +1 more source

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