Marburg Virus Reverse Genetics Systems
Viruses, 2016 The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
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Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature [PDF]
, 2020 In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is
Aly, Besma +9 more
core
Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 [PDF]
, 2014 In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa.
Andersen, Kristian G. +43 more
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Investigation of the Lipid Binding Properties of the Marburg Virus Matrix Protein VP40 [PDF]
, 2015 Marburg virus (MARV), which belongs to the virus family Filoviridae, causes hemorrhagic fever in humans and nonhuman primates that is often fatal. MARV is a lipid-enveloped virus that during the replication process extracts its lipid coat from the plasma
Stahelin, Robert V. +1 more
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Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing
mBio, 2018 Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used cholesterol-lowering drugs, have pleiotropic mechanisms of action and were suggested as potential adjunct ...
Punya Shrivastava-Ranjan +7 more
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Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19
Frontiers in Immunology, 2023 Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber +2 more
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Cell Reports, 2023 Summary: Ebola virus (EBOV) and Bundibugyo virus (BDBV) belong to the family Filoviridae and cause a severe disease in humans. We previously isolated a large panel of monoclonal antibodies from B cells of human survivors from the 2007 Uganda BDBV ...
Rodrigo I. Santos +8 more
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Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone [PDF]
, 2017 A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of
Antonella Minutolo +13 more
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Plant phenology supports the multi-emergence hypothesis for ebola spillover events [PDF]
, 2017 Ebola virus disease outbreaks in animals (including humans and great apes) start with sporadic host switches from unknown reservoir species. The factors leading to such spillover events are little explored.
Douglas, Noah E. +6 more
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Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Viruses, 2012 Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger +6 more
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