Results 51 to 60 of about 4,010 (187)

Viral fossils in marsupial genomes: secret cellular guardians [PDF]

open access: yesMicrobiology Australia, 2021
Genomic viral integrations, termed endogenous viral elements (EVEs), are fragments of viruses in host chromosomes that provide information about viral evolution and could even help protect the host from infection. In the present study we examined EVEs in
Peter A White   +2 more
doaj  

Marburg Virus Reverse Genetics Systems

open access: yesViruses, 2016
The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
doaj   +1 more source

Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing

open access: yesmBio, 2018
Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used cholesterol-lowering drugs, have pleiotropic mechanisms of action and were suggested as potential adjunct ...
Punya Shrivastava-Ranjan   +7 more
doaj   +1 more source

Potential Vaccines and Post-Exposure Treatments for Filovirus Infections

open access: yesViruses, 2012
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger   +6 more
doaj   +1 more source

Ebola virus: A global public health menace: A narrative review

open access: yesJournal of Family Medicine and Primary Care, 2019
Ebola virus disease (EVD), a fatal viral hemorrhagic illness, is due to infection with the Ebola virus of the Filoviridae family. The disease has evolved as a global public health menace due to a large immigrant population.
Shamimul Hasan   +3 more
doaj   +1 more source

Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19

open access: yesFrontiers in Immunology, 2023
Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber   +2 more
doaj   +1 more source

Phosphatidylethanolamine: A key player in lung disease

open access: yesClinical and Translational Discovery, Volume 5, Issue 4, August 2025.
Implication of PE in the aetiology of diverse diseases. The pivotal role of PE in driving lipid peroxidation during ferroptosis. Implications of PE metabolic dysregulation in pulmonary epithelial cells. Abstract Phosphatidylethanolamine (PE) is a pivotal glycerophospholipid that constitutes a significant portion of cellular membranes, playing a crucial
Linlin Zhang, Wanxin Duan, Liyang Li
wiley   +1 more source

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Land Use Change and Infectious Disease Emergence

open access: yesReviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli   +6 more
wiley   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

open access: yesMedicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi   +9 more
wiley   +1 more source

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