Results 61 to 70 of about 3,948 (186)
Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015
Emerging Infectious Diseases, 2017 Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%–99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism.
Xing-Lou Yang +13 more
doaj +1 more source
Ebola virus disease: past, present and future
Asian Pacific Journal of Tropical Biomedicine, 2015 Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak +4 more
doaj +1 more source
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier +4 more
wiley +1 more source
CryoEM structure of the Nipah virus nucleocapsid assembly.
PLoS Pathogens, 2021 Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral immunogen.
De-Sheng Ker +3 more
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A public, cross‐reactive glycoprotein epitope confounds Ebola virus serology
Journal of Medical Virology, Volume 96, Issue 10, October 2024.Abstract Ebola disease (EBOD) in humans is a severe disease caused by at least four related viruses in the genus Orthoebolavirus, most often by the eponymous Ebola virus. Due to human‐to‐human transmission and incomplete success in treating cases despite promising therapeutic development, EBOD is a high priority in public health research.
Markus H. Kainulainen +17 more
wiley +1 more source
Проблемы особо опасных инфекций, 2018 Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova +2 more
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Ecography, Volume 2024, Issue 10, October 2024.Habitat degradation can increase zoonotic disease risks by altering infection dynamics in wildlife and increasing wildlife–human interactions. Bats are an important taxonomic group to consider these effects, because they harbour many relevant zoonotic viruses and have species‐ and context‐dependent responses to degradation that could affect zoonotic ...
Alexis M. Heckley +2 more
wiley +1 more source
Ebolavirus and Haemorrhagic Syndrome
Sultan Qaboos University Medical Journal, 2015 The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in
Gerald A. Matua +2 more
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Carbon‐Based Nanomaterials for Antiviral Applications
Advanced Functional Materials, Volume 34, Issue 38, September 18, 2024.Carbon‐based nanomaterials (CBNs), including fullerenes, carbon dots, graphene, and their derivatives, show promise as antiviral tools in the antimicrobial resistance era. They exhibit broad‐spectrum antiviral activity with a low risk of resistance development. CBNs also enhance efficacy under light exposure and support antiviral immune responses. CBNs
Ángel Serrano‐Aroca +3 more
wiley +1 more source
Ecology and Evolution, Volume 14, Issue 6, June 2024.Bats are reservoirs for emerging pathogens and may pose significant risks to human health. Understanding spatial overlap between bats and humans across landscapes is a necessary requirement for developing exposure prevention strategies against bat‐borne zoonotic pathogens.
Ruut J. Uusitalo +7 more
wiley +1 more source