Results 121 to 130 of about 11,014 (267)
Human and murine IFIT1 proteins do not restrict infection of negative-sense RNA viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae families [PDF]
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amarasinghe, Gaya +12 more
core +3 more sources
There are continuous efforts to improve total syntheses of natural products, particularly their sustainability, such as developing effective chiral pool approaches relying on a wide spectrum of natural chirons, including (−)‐sclareol as one of the most useful natural chirons.
Ayyoub Selka +5 more
wiley +1 more source
Filoviruses: One of These Things is (not) Like the Other
The family Filoviridae contains several of the most deadly pathogens known to date and the current Ebola virus disease (EVD) outbreak in Western Africa, due to Ebola virus (EBOV) infection, highlights the need for active and broad research into filovirus
Scott M. Anthony, Steven B. Bradfute
doaj +1 more source
Filoviruses, including Ebola, Marburg, Sudan, and Taï Forest viruses, are zoonotic pathogens that can cause severe viral hemorrhagic fever and death. Developing vaccines that provide durable, broad immunity against multiple filoviruses is a high global ...
C. Rostad +26 more
semanticscholar +1 more source
Ebolavirus evolution and emergence are associated with land use change
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange +8 more
wiley +1 more source
A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection. [PDF]
Asymptomatic ebolavirus infection could greatly influence transmission dynamics, but there is little consensus on how frequently it occurs or even if it exists. This paper summarises the available evidence on seroprevalence of Ebola, Sudan and Bundibugyo
Bower, Hilary, Glynn, Judith R
core +2 more sources
There are a number of vaccine candidates under development against a small number of the most common outbreak filoviruses all employing the virus glycoprotein (GP) as the vaccine immunogen.
Md Niaz Rahim +11 more
doaj +1 more source
TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine [PDF]
Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue ...
Ahmed, Asim Aminsharif +11 more
core +3 more sources
Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir
The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screening ...
Jason E. Comer +11 more
doaj +1 more source
Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999. [PDF]
Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo.
Borchert, M +10 more
core +2 more sources

