Results 101 to 110 of about 6,479 (200)

Filovirus surveillance of bats in Zambia

open access: yes, 2018
Bats are suspected to play important roles in the ecology of filoviruses, including ebolaviruses and marburgviruses. A cave-dwelling fruit bat, Rousettus aegyptiacus, has been shown to be a reservoir of marburgviruses.
Qiu, Yongjin   +51 more
core   +1 more source

Production of Filovirus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus for Study of Filovirus Entry Mechanisms

open access: yes, 2017
Members of the family Filoviridae are filamentous, enveloped, and nonsegmented negative-stranded RNA viruses that can cause severe hemorrhagic disease in humans and nonhuman primates with high mortality rates. Current efforts to analyze the structure and biology of these viruses as well as the development of antivirals have been hindered by the ...
Rachel B, Brouillette, Wendy, Maury
openaire   +3 more sources

Peripheral immune responses to filoviruses in a reservoir versus spillover hosts reveal transcriptional correlates of disease

open access: yesFrontiers in Immunology
Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito   +13 more
doaj   +1 more source

Evolutionary maintenance of filovirus-like genes in bat genomes

open access: yes, 2011
Background Little is known of the biological significance and evolutionary maintenance of integrated non-retroviral RNA virus genes in eukaryotic host genomes.
Derek J Taylor   +7 more
core   +1 more source

Emerging Challenges in Filovirus Infections

open access: yes, 2020
This book discusses the emerging challenges of the filovirus infections Ebola and Marburg virus disease. It reviews the complex ecology and role played by bats and other suspected intermediate hosts, including pigs.

core   +1 more source

Doença Causada por Filovírus: Uma Atualização

open access: yesActa Médica Portuguesa
Os vírus Marburgo e Ébola pertencem à família Filoviridae e são conhecidos por causar doenças zoonóticas emergentes. Estes vírus apresentam alta letalidade e são facilmente transmissíveis de pessoa para pessoa, o que os torna potencialmente capazes de ...
Rafael Marx de Andrade   +3 more
doaj   +1 more source

Filovirus infections: science and innovation

open access: yesСибирский научный медицинский журнал
Epidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva   +2 more
doaj   +1 more source

Production and Purification of Filovirus Glycoproteins in Insect and Mammalian Cell Lines

open access: yes, 2017
Filoviruses are highly virulent pathogens capable of causing severe disease. The glycoproteins of filoviruses are the only virally expressed proteins on the virion surface and are required for receptor binding.
Derek Rinaldi   +12 more
core   +1 more source

A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus

open access: yeseLife
Marburg virus (MARV) is one of the filovirus species that cause deadly hemorrhagic fever in humans, with mortality rates up to 90%. Neutralizing antibodies represent ideal candidates to prevent or treat virus disease.
Yuting Zhang   +17 more
doaj   +1 more source

The trait profile of filovirus-positive bat species.

open access: yes, 2016
Partial dependence plots of the top 8 predictor variables from a generalized boosted regression analysis illustrate the trait profile of bat species that are positive for filoviruses in the wild.
Sarah E. Bowden (3153924)   +5 more
core   +1 more source

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