Results 81 to 90 of about 6,894 (200)
Mécanismes d’échappement des filovirus à l’immunité innée [PDF]
, 2018 International audienceEbola virus is an important pathogen that emerged in Central Africa where it was responsible of numerous outbreaks of haemorrhagic fevers associated with a extremely high mortality rate (up to 90%).
Baptiste Martin +3 more
core +1 more source
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Small Science, Volume 6, Issue 1, January 2026.Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2016 BackgroundThe 2013-15 Ebola outbreak was unprecedented due to sustained transmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance about
Julii Brainard +4 more
doaj +1 more source
Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, Volume 121, Issue 7, Page 923-926, July 2026.
Pierre Tiberghien +4 more
wiley +1 more source
In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP‐40
BioMed Research International, Volume 2026, Issue 1, 2026.The continued reemergence of Ebola virus epidemics remains a global health concern, largely due to limited therapeutic interventions. This study is aimed at identifying and characterizing antiviral peptides as potential lead candidates against the Sudan Ebola virus.
Boniface Omara +13 more
wiley +1 more source
PLoS Pathogens, 2019 There are a number of vaccine candidates under development against a small number of the most common outbreak filoviruses all employing the virus glycoprotein (GP) as the vaccine immunogen.
Md Niaz Rahim +11 more
doaj +1 more source
Positive Selection Drives Evolution at the Host-Filovirus Interaction Surface
, 2016 Filovirus infection is mediated by engagement of the surface-exposed glycoprotein (GP) by its cellular receptor, NPC1 (Niemann-Pick C1). Two loops in the C domain of NPC1 (NPC1-C) bind filovirus GP.
M. Clerici +7 more
core +1 more source
Discovery of an Ebolavirus-Like Filovirus in Europe
PLoS Pathogens, 2011 (Uploaded by Plazi for the Bat Literature Project) Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease.
Negredo, Ana +16 more
openaire +9 more sources
Filoviruses belong to a virus family called Filoviridae and can cause severe hemorrhagic fever in humans and nonhuman primates. So far, only two members of this virus family have been identified: Marburg virus and Ebola virus. Four species of Ebola virus
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