Results 71 to 80 of about 6,894 (200)

Cellular Factors Implicated in Filovirus Entry [PDF]

Advances in Virology, 2013
Although filoviral infections are still occurring in different parts of the world, there are no effective preventive or treatment strategies currently available against them. Not only do filoviruses cause a deadly infection, but they also have the potential of being used as biological weapons.
Suchita Bhattacharyya, Thomas J. Hope
openaire   +3 more sources

Investigating Filovirus Expression in Monodelphis domestica

, 2015
In this study, we explored the expression of a filovirus nucleoprotein (NP) gene and a filovirus RNA dependent RNA polymerase (L) gene in Monodelphis domestica. While we know that these filovirus genes are maintained within M.
Stuff, Daniel
core   +1 more source

Identification of Filovirus Entry Inhibitors from Marine Fungus-Derived Indole Alkaloids

Marine Drugs
Filoviruses, mainly consisting of the two genera of Ebolavirus and Marburgvirus, are enveloped negative-strand RNA viruses that can infect humans to cause severe hemorrhagic fevers and outbreaks with high mortality rates.
Leah Liu Wang, Javier Seravalli, Brett Eaton, Yi Liu, Michael R. Holbrook, Wen-Jian Lan, Shi-Hua Xiang   +6 more
doaj   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, Volume 39, Issue 3, Page 346-367, April 2026.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

mBio, 2016
The filovirus surface glycoprotein (GP) mediates viral entry into host cells. Following viral internalization into endosomes, GP is cleaved by host cysteine proteases to expose a receptor-binding site (RBS) that is otherwise hidden from immune ...
Zachary A. Bornholdt, Esther Ndungo, Marnie L. Fusco, Shridhar Bale, Andrew I. Flyak, James E. Crowe, Kartik Chandran, Erica Ollmann Saphire   +7 more
doaj   +1 more source

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

New filovirus disease classification and nomenclature [PDF]

Nature Reviews Microbiology, 2019
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Kuhn, Jens H., Adachi, Takuya, Adhikari, Neill K.J., Arribas, Jose R., Bah, Ibrahima E., Bausch, Daniel G., Bhadelia, Nahid, Borchert, Matthias, Brantsæter, Arne Broch, Brett-Major, David M., Burgess, Timothy H., Castro-Ria, Lado Marta, Chertow, Daniel S., Chute, Christopher G., Cieslak, Theodore J., Colebunders, Robert, Crozier, Ian, Davey, Richard T., De Clerck, Hilde, Delgado, Rafael, Evans, Laura, Fallah, Mosoka, Fischer, William A., II, Fischer, Fletcher, Tom E., Fowler, Robert A., Grunewald, Thomas, Hall, Andy, Hewlett, Angela, Hoepelman, Andy I.M., Houlihan. Catherine F., Ippolito, Giuseppe, Jacob, Shevin T., Jacobs, Michael, Jakob, Robert, Jacquerioz, Frederique A., Kaiser, Laurent, Kalil, Andre C., Kamara, Rashidatu F., Kapetshi, Jimmy, Klenk, Hans-Dieter, Kobinger, Gary, Kortepeter, Mark G., Kraft, Colleen S., Kratz, Thomas, Bosa, Henry S. Kyobe, Lamontagne, Francois, Lane, H. Cliff, Lobel, Leslie, Lutwama, Julius, III, G. Marshall Lyon, Massaquoi, Moses B.F., Massaquoi, Thomas A., Mehta, Aneesh K., Makuma, Vital Mondonge, Murthy, Srinivas, Musoke, Tonny Seikikongo, Muyembe-Tamfum, Jean-Jacques, Nakyeyune, Phiona, Nanclares, Carolina, Nanyunja, Miriam, Nsio-Mbeta, Justus, O’Dempsey, Tim, Pawęska, Janusz T., Peters, Clarence J., Piot, Peter, Rapp, Christophe, Renaud, Bertrand, Ribner, Bruce, Sabeti, Pardis C., Schieffelin, John S., Slenczka, Werner, Soka, Moses J., Sprecher, Armand, Strong, James, Swanepoel, Robert, Uyeki, Timothy M., Van Herp, Michel, Vetter, Pauline, Wohl, David A., Wolf, Timo, Wolz, Anja, Wurie, Alie H., Yoti, Zabulon   +83 more
openaire   +9 more sources

A small nonhuman primate model for filovirus-induced disease [PDF]

, 2011
Ebolavirus and Marburgvirus are members of the filovirus family and induce a fatal hemorrhagic disease in humans and nonhuman primates with 90% case fatality.
Mansfield, Keith, Patterson, Jean L., Ticer, Anysha, Ricardo Carrion, Brasky, Kathy, de la Garza, Melissa, Youngtae Ro, Kareema Hoosien, Anysha Ticer, Ro, Youngtae, Kathy Brasky, Jean L. Patterson, Hoosien, Kareema, Keith Mansfield, Carrion, Ricardo, Melissa de la Garza   +15 more
core   +1 more source

Filoviruses: One of These Things is (not) Like the Other

Viruses, 2015
The family Filoviridae contains several of the most deadly pathogens known to date and the current Ebola virus disease (EVD) outbreak in Western Africa, due to Ebola virus (EBOV) infection, highlights the need for active and broad research into filovirus
Scott M. Anthony, Steven B. Bradfute
doaj   +1 more source

Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology

Journal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley, Caylee A. Falvo, Chris K. Grant, Benny Borremans, Tamika J. Lunn, Manuel Ruiz‐Aravena, Evelyn Benson, Clifton D. McKee, Daniel J. Becker, Devin N. Jones, Trenton Bushmaker, Y. Tina Yu, Michelle Michie, Adrienne S. Dale, Lianying Yan, Spencer L. Sterling, Christopher C. Broder, Laura B. Goodman, Rasa Petraityte‐Burneikiene, Eric D. Laing, Ina L. Smith, Vincent J. Munster, Agnieszka Rynda‐Apple, Alison J. Peel, Raina Plowright   +24 more
wiley   +1 more source