Results 51 to 60 of about 7,064 (200)

Mathematical Modeling of Pulse‐Seeded Metapopulation Dynamics for Andes Hantavirus Border Dispersal

Engineering Reports, Volume 8, Issue 9, September 2026.
A pulse‐seeded metapopulation SEIR model for Andes hantavirus maritime dispersal shows that heterogeneous quarantine compliance determines secondary outbreak risk. The weakest‐compliance country governs global containment, while uniform compliance above ∼65%$$ \sim 65\% $$ reduces the global reproduction number below unity.
Gideon K. Gogovi, Paul Chataa
wiley   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, Volume 3, Issue 3, September 2026.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Filovirus Hemorrhagic Fever Outbreak Case Management: A Review of Current and Future Treatment Options [PDF]

, 2011
: Testing an innovative therapy for filovirus hemorrhagic fever (FHF) in an outbreak setting may be years away. Moreover, beyond anecdotal evidence, little is known about best practice for outbreak case management.
Borchert, M., Roddy, Paul, Jeffs, B., Robert Colebunders, Benjamin Jeffs, van Herp, Michel, Van Herp, M., Pedro Pablo Palma, Roddy, P., Jeffs, Benjamin, Colebunders, Robert, Matthias Borchert, Paul Roddy, Palma, P. P., Borchert, Matthias, Colebunders, R., Michel Van Herp, Palma, Pedro Pablo   +17 more
core   +1 more source

Tuning the Length of Filomicelles Prepared Via Templated Polymerization‐Induced Self‐Assembly

Small, Volume 22, Issue 51, 11 September 2026.
High‐aspect‐ratio polymeric micelles are attractive yet notoriously difficult to control in length. We reveal a counterintuitive and powerful solution: in supramolecularly templated PISA, adding non‐sticker polymer unexpectedly elongates the micelles, while post‐assembly sonication enables precise shortening with reduced dispersity.
Eleonora G. Hochreiner, Wiktoria Pioruńska, Gaëlle Mellot, Bence Fehér, Jean‐Michel Guigner, Viktoriia Drebezghova, Christophe Sinturel, Cornelus F. van Nostrum, Tina Vermonden, Jutta Rieger, Bas G. P. van Ravensteijn   +10 more
wiley   +1 more source

Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors

Viruses, 2019
Filoviruses infect a wide range of cell types with the exception of lymphocytes. The intracellular proteins cathepsin B and L, two-pore channel 1 and 2, and bona fide receptor Niemann–Pick Disease C1 (NPC1) are essential for the endosomal phase of ...
Francisco J. Zapatero-Belinchón, Erik Dietzel, Olga Dolnik, Katinka Döhner, Rui Costa, Barbara Hertel, Barbora Veselkova, Jared Kirui, Anneke Klintworth, Michael P. Manns, Stefan Pöhlmann, Thomas Pietschmann, Thomas Krey, Sandra Ciesek, Gisa Gerold, Beate Sodeik, Stephan Becker, Thomas von Hahn   +17 more
doaj   +1 more source

Fixing Epidemic Risk, Fixing Epidemic Spacetime? How Emerging Disease Science Writes Wild Stories About Pandemic Origins

Antipode, Volume 58, Issue 5, September 2026.
ABSTRACT Using the US Agency for International Development (USAID) PREDICT program as a case study, I argue that mainstream emerging disease science (re)produces Orientalist imaginaries of pandemic risk through narratives about wildlife infections as inherently “backwards” in epidemic time relative to human and domestic animal infections. This temporal
Mollie Holmberg
wiley   +1 more source

Novel Small Molecule Therapeutics and Mechanisms of Action for the Treatment of Filovirus Diseases [PDF]

, 2021
Filoviruses are among the deadliest diseases known to mankind with mortality rates up to 90%. Furthermore, new filoviruses are being discovered in areas such as China where they had not previously been reported.
Adam Michael Schafer (11298372)
core   +1 more source

Development and evaluation of a panel of filovirus sequence capture probes for pathogen detection by next-generation sequencing. [PDF]

PLoS ONE, 2014
A detailed understanding of the circulating pathogens in a particular geographic location aids in effectively utilizing targeted, rapid diagnostic assays, thus allowing for appropriate therapeutic and containment procedures.
Jeffrey W Koehler, Adrienne T Hall, P Alexander Rolfe, Anna N Honko, Gustavo F Palacios, Joseph N Fair, Jean-Jacques Muyembe, Prime Mulembekani, Randal J Schoepp, Adeyemi Adesokan, Timothy D Minogue   +10 more
doaj   +1 more source

Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles

Traffic, Volume 27, Issue 3, September 2026.
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto, Amir Fardin, Matteo Balestra, Pier Paolo Di Fiore, Chiara Tordonato, Sara Sigismund   +5 more
wiley   +1 more source

Magnified range maps of known and predicted filovirus-positive bat species.

, 2016
Magnifications of hotspots of filovirus-positive bat species in sub-Saharan Africa (left), and hotspots in Southeast Asia showing overlapping geographic ranges for predicted new filovirus carriers within the 90th percentile probability (right).
Sarah E. Bowden (3153924), John M. Drake (67554), Laura W. Alexander (683272), Barbara A. Han (294479), David T. S. Hayman (188106), John Paul Schmidt (224953)   +5 more
core   +1 more source