Results 41 to 50 of about 7,064 (200)
Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing? [PDF]
, 2000 The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda.
Boelaert, M +24 more
core +1 more source
, 2013 A number of advances in recent years have significantly furthered our understanding of filovirus attachment and cellular tropism. For example, several cell-surface molecules have been identified as attachment factors with the potential to facilitate the in vivo targeting of particular cell types such as macrophages and hepatic cells.
openaire +2 more sources
Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors
Cell Reports, 2018 Summary: Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can protect against infection. It is currently unknown whether natural infection also induces some antibodies with the capacity for antibody-dependent enhancement
Natalia A. Kuzmina +10 more
doaj +1 more source
BMC Infectious Diseases, 2020 Background Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining ...
Luke Nyakarahuka +10 more
doaj +1 more source
Filovirus Replication and Transcription [PDF]
Future Virology, 2007 The highly pathogenic filoviruses, Marburg and Ebola virus, belong to the nonsegmented negative-sense RNA viruses of the order Mononegavirales. The mode of replication and transcription is similar for these viruses. On one hand, the negative-sense RNA genome serves as a template for replication, to generate progeny genomes, and, on the other hand, for ...
openaire +2 more sources
Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates.
PLoS ONE, 2014 The filoviruses, Marburg virus (MARV) and Ebola virus, causes severe hemorrhagic fever with high mortality in humans and nonhuman primates. A promising filovirus vaccine under development is based on a recombinant vesicular stomatitis virus (rVSV) that ...
Chad E Mire +8 more
doaj +1 more source
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Immunology &Cell Biology, EarlyView.Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
IFITM3 Is Elevated in BAL and Plasma Following Infection in ICU Setting
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.IFITM3 levels in BAL and plasma of critically ill patients. ABSTRACT Interferon‐induced transmembrane protein 3 (IFITM3) is an antiviral protein with emerging roles in regulating inflammatory pathways. Although much is known about the role of IFITM3 in mediating host antiviral defense, its contribution to systemic immune responses during critical ...
Srabani Das +4 more
wiley +1 more source
Clinical documentation and data transfer from Ebola and Marburg virus disease wards in outbreak settings: health care workers' experiences and preferences. [PDF]
, 2014 Understanding human filovirus hemorrhagic fever (FHF) clinical manifestations and evaluating treatment strategies require the collection of clinical data in outbreak settings, where clinical documentation has been limited.
Roddy, Paul +7 more
core +1 more source
BMC Infectious Diseases, 2018 Background Ebolavirus and Marburgvirus are genera of the virus family Filoviridae. Filoviruses cause rare but fatal viral hemorrhagic fevers (VHFs) in remote villages of equatorial Africa with potential for regional and international spread.
Peace Babirye +9 more
doaj +1 more source