Results 41 to 50 of about 6,894 (200)

Filovirus Entry [PDF]

, 2013
A number of advances in recent years have significantly furthered our understanding of filovirus attachment and cellular tropism. For example, several cell-surface molecules have been identified as attachment factors with the potential to facilitate the in vivo targeting of particular cell types such as macrophages and hepatic cells.
openaire   +2 more sources

Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover - Fig 2

, 2019
MFI values for sera obtained from humans (A), Eonycteris spelaea (B), Rousettus leschenaultii (C). Antibodies reactive to filovirus GPe from Ebola virus (EBOV), Bundibugyo virus (BDBV), Taï Forest virus (TAFV), Sudan ebolavirus (SUDV), Reston virus ...
B. R. Ansil (7609943), Uma Ramakrishnan (4564), Eric D. Laing (7609940), Yihui Chen (446576), Christopher C. Broder (7609946), Ian H. Mendenhall (7470851), Zhengli Shi (203756), Gavin J. D. Smith (6872954), Pilot Dovih (7609937), Xinglou Yang (6368906), Dolyce H. W. Low (4172911), Martin Linster (343086)   +11 more
core   +1 more source

A high-throughput, polymerase-targeted RT-PCR for broad detection of mammalian filoviruses

Microbiology Spectrum
Filoviruses are some of the most lethal viruses in the modern world, and increasing numbers of filovirus species and genera have been discovered in recent years.
Na Cui, Yael L. Perez, Adam J. Hume, B. Ethan Nunley, Kevin Kong, Margaret G. Mills, Hong Xie, Alexander L. Greninger   +7 more
doaj   +1 more source

Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors

Cell Reports, 2018
Summary: Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can protect against infection. It is currently unknown whether natural infection also induces some antibodies with the capacity for antibody-dependent enhancement
Natalia A. Kuzmina, Patrick Younan, Pavlo Gilchuk, Rodrigo I. Santos, Andrew I. Flyak, Philipp A. Ilinykh, Kai Huang, Ndongala M. Lubaki, Palaniappan Ramanathan, James E. Crowe, Jr., Alexander Bukreyev   +10 more
doaj   +1 more source

A retrospective cohort investigation of seroprevalence of Marburg virus and ebolaviruses in two different ecological zones in Uganda

BMC Infectious Diseases, 2020
Background Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining ...
Luke Nyakarahuka, Ilana J. Schafer, Stephen Balinandi, Sophia Mulei, Alex Tumusiime, Jackson Kyondo, Barbara Knust, Julius Lutwama, Pierre Rollin, Stuart Nichol, Trevor Shoemaker   +10 more
doaj   +1 more source

Filovirus Replication and Transcription [PDF]

Future Virology, 2007
The highly pathogenic filoviruses, Marburg and Ebola virus, belong to the nonsegmented negative-sense RNA viruses of the order Mononegavirales. The mode of replication and transcription is similar for these viruses. On one hand, the negative-sense RNA genome serves as a template for replication, to generate progeny genomes, and, on the other hand, for ...
openaire   +2 more sources

Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover

, 2019
Bats are reservoirs for several zoonotic pathogens, including filoviruses. Recent work highlights the diversity of bat borne filoviruses in Asia. High risk activities at the bat-human interface pose the threat of zoonotic virus transmission.
B. R. Ansil (7609943), Ansil, B. R., Yihui Chen (446576), Pilot Dovih (7609937), Xinglou Yang (6368906), Dolyce H. W. Low (4172911), Mendenhall, I.H., Mendenhall, Ian H., Yang, X., Broder, Christopher C., Eric D. Laing (7609940), Low, D.H.W., Chen, Yihui, Laing, Eric D., Martin Linster (343086), Dovih, Pilot, Mossel, Eric, Smith, G.J.D., Ramakrishnan, U., Christopher C. Broder (7609946), Ian H. Mendenhall (7470851), Ramakrishnan, Uma, Gavin J. D. Smith (6872954), Chen, Y., Shi, Z., Linster, M., Uma Ramakrishnan (4564), Broder, C.C., Laing, E.D., Shi, Zhengli, Ansil, B.R., Zhengli Shi (203756), Yang, Xinglou, Dovih, P., Linster, Martin, Low, Dolyce H. W., Smith, Gavin J. D.   +36 more
core   +1 more source

Endocytic Pathways Involved in Filovirus Entry: Advances, Implications and Future Directions

Viruses, 2012
Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify determinants of viral virulence and host range, and to yield targets for the development of antiviral therapeutics.
Suchita Bhattacharyya, Kartik Chandran, Nirupama Mulherkar   +2 more
doaj   +1 more source

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates.

PLoS ONE, 2014
The filoviruses, Marburg virus (MARV) and Ebola virus, causes severe hemorrhagic fever with high mortality in humans and nonhuman primates. A promising filovirus vaccine under development is based on a recombinant vesicular stomatitis virus (rVSV) that ...
Chad E Mire, Joan B Geisbert, Krystle N Agans, Benjamin A Satterfield, Krista M Versteeg, Elizabeth A Fritz, Heinz Feldmann, Lisa E Hensley, Thomas W Geisbert   +8 more
doaj   +1 more source

Mathematical Modeling of Pulse‐Seeded Metapopulation Dynamics for Andes Hantavirus Border Dispersal

Engineering Reports, Volume 8, Issue 9, September 2026.
A pulse‐seeded metapopulation SEIR model for Andes hantavirus maritime dispersal shows that heterogeneous quarantine compliance determines secondary outbreak risk. The weakest‐compliance country governs global containment, while uniform compliance above ∼65%$$ \sim 65\% $$ reduces the global reproduction number below unity.
Gideon K. Gogovi, Paul Chataa
wiley   +1 more source