Results 21 to 30 of about 7,064 (200)

Filovirus infections in travellers

Filovirus disease (FVD) outbreaks present significant public health challenges when they occur in West and Central Africa. FVD includes Ebola and Marburg disease that carry high case fatality rates and significant nosocomial risk, with limited proven ...
Fletcher, Tom
core   +2 more sources

Elucidation of molecular mechanism of filovirus entry.

, 2005
Elucidation of molecular mechanism of filovirus ...
Balaji. Manicassamy (7977065)
core   +4 more sources

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates. [PDF]

PLoS ONE, 2018
The search for a universal filovirus vaccine that provides protection against multiple filovirus species has been prompted by sporadic but highly lethal outbreaks of Ebolavirus and Marburgvirus infections.
Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn   +20 more
doaj   +1 more source

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses

Viruses, 2017
The mononegaviral family Filoviridae has eight members assigned to three genera and seven species. Until now, genus and species demarcation were based on arbitrarily chosen filovirus genome sequence divergence values (≈50% for genera, ≈30% for species ...
Yīmíng Bào, Gaya K. Amarasinghe, Christopher F. Basler, Sina Bavari, Alexander Bukreyev, Kartik Chandran, Olga Dolnik, John M. Dye, Hideki Ebihara, Pierre Formenty, Roger Hewson, Gary P. Kobinger, Eric M. Leroy, Elke Mühlberger, Sergey V. Netesov, Jean L. Patterson, Janusz T. Paweska, Sophie J. Smither, Ayato Takada, Jonathan S. Towner, Viktor E. Volchkov, Victoria Wahl-Jensen, Jens H. Kuhn   +22 more
doaj   +1 more source

Assays for the Evaluation of the Immune Response to Marburg and Ebola Sudan Vaccination—Filovirus Animal Nonclinical Group Anti-Marburg Virus Glycoprotein Immunoglobulin G Enzyme-Linked Immunosorbent Assay and a Pseudovirion Neutralization Assay

Vaccines, 2022
Since the discovery of the Marburg virus (MARV) in 1967 and Ebola virus (EBOV) in 1976, there have been over 40 reported outbreaks of filovirus disease with case fatality rates greater than 50%.
Thomas L. Rudge, Nicholas J. Machesky, Karen A. Sankovich, Erin E. Lemmon, Christopher S. Badorrek, Rachel Overman, Nancy A. Niemuth, Michael S. Anderson   +7 more
doaj   +1 more source

Identifying Suspect Bat Reservoirs of Emerging Infections

Vaccines, 2020
Bats host a number of pathogens that cause severe disease and onward transmission in humans and domestic animals. Some of these pathogens, including henipaviruses and filoviruses, are considered a concern for future pandemics.
Daniel Crowley, Daniel Becker, Alex Washburne, Raina Plowright   +3 more
doaj   +1 more source

Filoviruses are ancient and integrated into mammalian genomes

BMC Evolutionary Biology, 2010
Background Hemorrhagic diseases from Ebolavirus and Marburgvirus (Filoviridae) infections can be dangerous to humans because of high fatality rates and a lack of effective treatments or vaccine.
Bruenn Jeremy, Leach Robert W, Taylor Derek J   +2 more
doaj   +1 more source

Assembly and transport of filovirus nucleocapsids

PLOS Pathogens, 2022
Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is induced mainly by the accumulation of the filoviral nucleoprotein NP, which recruits the other nucleocapsid proteins, the polymerase co-factor VP35, the polymerase L, the transcription factor VP30 and
Olga Dolnik, Stephan Becker
openaire   +3 more sources

Challenges, Progress, and Opportunities: Proceedings of the Filovirus Medical Countermeasures Workshop

Viruses, 2014
On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filovirus ...
Rona Hirschberg, Lucy A. Ward, Nicole Kilgore, Rebecca Kurnat, Helen Schiltz, Mark T. Albrecht, George W. Christopher, Ed Nuzum   +7 more
doaj   +1 more source

Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis). [PDF]

J Fish Dis
Journal of Fish Diseases, Volume 49, Issue 5, May 2026.
Perschthaler J, Wildi N, Matthiss LK, Seuberlich T, Schmidt-Posthaus H.   +4 more
europepmc   +2 more sources