Results 11 to 20 of about 5,548 (176)

Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis). [PDF]

J Fish Dis
Journal of Fish Diseases, Volume 49, Issue 5, May 2026.
Perschthaler J, Wildi N, Matthiss LK, Seuberlich T, Schmidt-Posthaus H.   +4 more
europepmc   +2 more sources

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses

Viruses, 2017
The mononegaviral family Filoviridae has eight members assigned to three genera and seven species. Until now, genus and species demarcation were based on arbitrarily chosen filovirus genome sequence divergence values (≈50% for genera, ≈30% for species ...
Yīmíng Bào, Gaya K. Amarasinghe, Christopher F. Basler, Sina Bavari, Alexander Bukreyev, Kartik Chandran, Olga Dolnik, John M. Dye, Hideki Ebihara, Pierre Formenty, Roger Hewson, Gary P. Kobinger, Eric M. Leroy, Elke Mühlberger, Sergey V. Netesov, Jean L. Patterson, Janusz T. Paweska, Sophie J. Smither, Ayato Takada, Jonathan S. Towner, Viktor E. Volchkov, Victoria Wahl-Jensen, Jens H. Kuhn   +22 more
doaj   +1 more source

Identifying Suspect Bat Reservoirs of Emerging Infections

Vaccines, 2020
Bats host a number of pathogens that cause severe disease and onward transmission in humans and domestic animals. Some of these pathogens, including henipaviruses and filoviruses, are considered a concern for future pandemics.
Daniel Crowley, Daniel Becker, Alex Washburne, Raina Plowright   +3 more
doaj   +1 more source

Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

Viruses, 2019
Filoviruses cause lethal hemorrhagic fever in humans. The filovirus nucleoprotein (NP) is expressed in high abundance in infected cells and is essential for virus replication.
Md Niaz Rahim, Min Wang, Tong Wang, Shihua He, Bryan D. Griffin, Darwyn Kobasa, Ruifu Yang, Zongmin Du, Xiangguo Qiu   +8 more
doaj   +1 more source

Assays for the Evaluation of the Immune Response to Marburg and Ebola Sudan Vaccination—Filovirus Animal Nonclinical Group Anti-Marburg Virus Glycoprotein Immunoglobulin G Enzyme-Linked Immunosorbent Assay and a Pseudovirion Neutralization Assay

Vaccines, 2022
Since the discovery of the Marburg virus (MARV) in 1967 and Ebola virus (EBOV) in 1976, there have been over 40 reported outbreaks of filovirus disease with case fatality rates greater than 50%.
Thomas L. Rudge, Nicholas J. Machesky, Karen A. Sankovich, Erin E. Lemmon, Christopher S. Badorrek, Rachel Overman, Nancy A. Niemuth, Michael S. Anderson   +7 more
doaj   +1 more source

Filoviruses are ancient and integrated into mammalian genomes

BMC Evolutionary Biology, 2010
Background Hemorrhagic diseases from Ebolavirus and Marburgvirus (Filoviridae) infections can be dangerous to humans because of high fatality rates and a lack of effective treatments or vaccine.
Bruenn Jeremy, Leach Robert W, Taylor Derek J   +2 more
doaj   +1 more source

Challenges, Progress, and Opportunities: Proceedings of the Filovirus Medical Countermeasures Workshop

Viruses, 2014
On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filovirus ...
Rona Hirschberg, Lucy A. Ward, Nicole Kilgore, Rebecca Kurnat, Helen Schiltz, Mark T. Albrecht, George W. Christopher, Ed Nuzum   +7 more
doaj   +1 more source

Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates. [PDF]

PLoS Neglected Tropical Diseases, 2012
The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (
Chad E Mire, Andrew D Miller, Angela Carville, Susan V Westmoreland, Joan B Geisbert, Keith G Mansfield, Heinz Feldmann, Lisa E Hensley, Thomas W Geisbert   +8 more
doaj   +1 more source

Undiscovered Bat Hosts of Filoviruses.

PLoS Neglected Tropical Diseases, 2016
Ebola and other filoviruses pose significant public health and conservation threats by causing high mortality in primates, including humans. Preventing future outbreaks of ebolavirus depends on identifying wildlife reservoirs, but extraordinarily high ...
Barbara A Han, John Paul Schmidt, Laura W Alexander, Sarah E Bowden, David T S Hayman, John M Drake   +5 more
doaj   +1 more source

Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity

Frontiers in Immunology, 2021
Multiple agents in the family Filoviridae (filoviruses) are associated with sporadic human outbreaks of highly lethal disease, while others, including several recently identified agents, possess strong zoonotic potential. Although viral glycoprotein (GP)-
Ariel S. Wirchnianski, Ariel S. Wirchnianski, Anna Z. Wec, Elisabeth K. Nyakatura, Andrew S. Herbert, Andrew S. Herbert, Megan M. Slough, Ana I. Kuehne, Eva Mittler, Rohit K. Jangra, Jonathan Teruya, John M. Dye, Jonathan R. Lai, Kartik Chandran   +13 more
doaj   +1 more source