Results 11 to 20 of about 6,479 (200)

Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]

open access: yesViruses, 2014
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists. Sequencing duration and costs are rapidly decreasing, sequencing hardware is under modification for use by non-experts, and software is constantly being improved to ...
Jens Kuhn   +75 more
core   +13 more sources

Establishment of pseudovirus infection mouse models for in vivo pharmacodynamics evaluation of filovirus entry inhibitors

open access: yesActa Pharmaceutica Sinica B, 2018
Filoviruses cause severe and fatal viral hemorrhagic fever in humans. Filovirus research has been extensive since the 2014 Ebola outbreak. Due to their high pathogenicity and mortality, live filoviruses require Biosafety Level-4 (BSL-4) facilities, which
Qing Chen   +4 more
doaj   +2 more sources

Clinical Management of Filovirus-Infected Patients

open access: yesViruses, 2012
Filovirus infection presents many unique challenges to patient management. Currently no approved treatments are available, and the recommendations for supportive care are not evidence based.
Danielle V. Clark   +2 more
doaj   +2 more sources

Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

open access: yesViruses, 2019
Filoviruses cause lethal hemorrhagic fever in humans. The filovirus nucleoprotein (NP) is expressed in high abundance in infected cells and is essential for virus replication.
Md Niaz Rahim   +8 more
doaj   +2 more sources

Potential Mammalian Filovirus Reservoirs [PDF]

open access: yesEmerging Infectious Diseases, 2004
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Peterson, A. Townsend   +3 more
openaire   +4 more sources

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats [PDF]

open access: yeseLife, 2015
Biological factors that influence the host range and spillover of Ebola virus (EBOV) and other filoviruses remain enigmatic. While filoviruses infect diverse mammalian cell lines, we report that cells from African straw-colored fruit bats (Eidolon helvum)
Melinda Ng   +20 more
doaj   +2 more sources

Filovirus Disease Outbreaks: A Chronological Overview [PDF]

open access: yesVirology: Research and Treatment, 2019
Filoviruses cause outbreaks which lead to high fatality in humans and non-human primates, thus tagging them as major threats to public health and species conservation. In this review, we give account of index cases responsible for filovirus disease outbreaks that have occurred over the past 52 years in a chronological fashion, by describing the ...
Sylvester Languon, Osbourne Quaye
openaire   +5 more sources

A Call to Action to Enhance Filovirus Disease Outbreak Preparedness and Response

open access: yesViruses, 2014
The frequency and magnitude of recognized and declared filovirus-disease outbreaks have increased in recent years, while pathogenic filoviruses are potentially ubiquitous throughout sub-Saharan Africa.
Paul Roddy
doaj   +2 more sources

Intracellular Events and Cell Fate in Filovirus Infection

open access: yesViruses, 2011
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Elena Ryabchikova   +3 more
doaj   +2 more sources

An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures

open access: yesViruses, 2012
The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj   +2 more sources

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