Results 91 to 100 of about 6,479 (200)
A small nonhuman primate model for filovirus-induced disease
, 2011 Ebolavirus and Marburgvirus are members of the filovirus family and induce a fatal hemorrhagic disease in humans and nonhuman primates with 90% case fatality.
Mansfield, Keith +15 more
core +1 more source
Filoviruses belong to a virus family called Filoviridae and can cause severe hemorrhagic fever in humans and nonhuman primates. So far, only two members of this virus family have been identified: Marburg virus and Ebola virus. Four species of Ebola virus
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Filovirus Strategies to Escape Antiviral Responses [PDF]
, 2017 This chapter describes the various strategies filoviruses use to escape host immune responses with a focus on innate immune and cell death pathways. Since filovirus replication can be efficiently blocked by interferon (IFN), filoviruses have evolved mechanisms to counteract both type I IFN induction and IFN response signaling pathways.
Judith, Olejnik +5 more
openaire +2 more sources
Mécanismes d’échappement des filovirus à l’immunité innée
, 2018 International audienceEbola virus is an important pathogen that emerged in Central Africa where it was responsible of numerous outbreaks of haemorrhagic fevers associated with a extremely high mortality rate (up to 90%).
Baptiste Martin +3 more
core +1 more source
Magnified range maps of known and predicted filovirus-positive bat species.
, 2016 Magnifications of hotspots of filovirus-positive bat species in sub-Saharan Africa (left), and hotspots in Southeast Asia showing overlapping geographic ranges for predicted new filovirus carriers within the 90th percentile probability (right).
Sarah E. Bowden (3153924) +5 more
core +1 more source
Intracellular events and cell fate in filovirus infection
, 2021 Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Olejnik J.
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Evasion of the Interferon-Mediated Antiviral Response by Filoviruses
Viruses, 2010 The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
doaj +1 more source
Elucidation of molecular mechanism of filovirus entry.
, 2005 Elucidation of molecular mechanism of filovirus ...
Balaji. Manicassamy (7977065)
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Summary of filovirus sequelae and persistence in animal models.
Summary of filovirus sequelae and persistence in animal models.
Andrea Marzi (146489) +1 more
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Discovery of sclareol and sclareolide as filovirus entry inhibitors
, 2019 Filoviruses cause severe hemorrhagic fever in humans. Ebola virus (EBOV) is the most contagious filovirus. Although compassionate treatments have been used during the latest Ebola outbreak, novel anti-EBOV agents are still urgently needed. In this study,
Ke Tang (39453) +2 more
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