Results 91 to 100 of about 7,064 (200)
Filovirus tropism: Cellular molecules for viral entry
Frontiers in Microbiology, 2012 In human and nonhuman primates, filoviruses (Ebola and Marburg viruses) cause severe hemorrhagic fever．Recently, other animals such as pigs and some species of fruit bats have also been shown to be susceptible to these viruses. While having a preference
Ayato eTakada
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Evolutionary maintenance of filovirus-like genes in bat genomes [PDF]
, 2011 Background Little is known of the biological significance and evolutionary maintenance of integrated non-retroviral RNA virus genes in eukaryotic host genomes.
Derek J Taylor +7 more
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Mécanismes d’échappement des filovirus à l’immunité innée
, 2018 International audienceEbola virus is an important pathogen that emerged in Central Africa where it was responsible of numerous outbreaks of haemorrhagic fevers associated with a extremely high mortality rate (up to 90%).
Baptiste Martin +3 more
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Evasion of the Interferon-Mediated Antiviral Response by Filoviruses
Viruses, 2010 The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
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Positive Selection Drives Evolution at the Host-Filovirus Interaction Surface
, 2016 Filovirus infection is mediated by engagement of the surface-exposed glycoprotein (GP) by its cellular receptor, NPC1 (Niemann-Pick C1). Two loops in the C domain of NPC1 (NPC1-C) bind filovirus GP.
M. Clerici +7 more
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Viral and host proteins that modulate filovirus budding
, 2010 The filoviruses, Ebola and Marburg, utilize a multifaceted mechanism for assembly and budding of infectious virions from mammalian cells. Growing evidence not only demonstrates the importance of multiple viral proteins for efficient assembly and budding,
Yuliang Liu, Ronald N Harty
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Frontiers in ChemistryEbola and Marburg viruses, biosafety level 4 pathogens, cause severe hemorrhaging and organ failure with high mortality. Although some FDA-approved vaccines or therapeutics like Ervebo for Zaire Ebola virus exist, still there is a lack of effective ...
W. Tamilarasi, B. J. Balamurugan
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Filovirus infections: science and innovation
Сибирский научный медицинский журналEpidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva +2 more
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Filoviruses belong to a virus family called Filoviridae and can cause severe hemorrhagic fever in humans and nonhuman primates. So far, only two members of this virus family have been identified: Marburg virus and Ebola virus. Four species of Ebola virus
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Frontiers in ImmunologySeveral filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito +13 more
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