Results 91 to 100 of about 6,894 (200)

Evolutionary maintenance of filovirus-like genes in bat genomes [PDF]

open access: yes, 2011
Background Little is known of the biological significance and evolutionary maintenance of integrated non-retroviral RNA virus genes in eukaryotic host genomes.
Derek J Taylor   +7 more
core   +1 more source

Evasion of the Interferon-Mediated Antiviral Response by Filoviruses

open access: yesViruses, 2010
The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
doaj   +1 more source

Magnified range maps of known and predicted filovirus-positive bat species.

open access: yes, 2016
Magnifications of hotspots of filovirus-positive bat species in sub-Saharan Africa (left), and hotspots in Southeast Asia showing overlapping geographic ranges for predicted new filovirus carriers within the 90th percentile probability (right).
Sarah E. Bowden (3153924)   +5 more
core   +1 more source

Intracellular events and cell fate in filovirus infection

open access: yes, 2021
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Olejnik J.
core  

New reverse sum Revan indices for physicochemical and pharmacokinetic properties of anti-filovirus drugs

open access: yesFrontiers in Chemistry
Ebola and Marburg viruses, biosafety level 4 pathogens, cause severe hemorrhaging and organ failure with high mortality. Although some FDA-approved vaccines or therapeutics like Ervebo for Zaire Ebola virus exist, still there is a lack of effective ...
W. Tamilarasi, B. J. Balamurugan
doaj   +1 more source

Filovirus infections: science and innovation

open access: yesСибирский научный медицинский журнал
Epidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva   +2 more
doaj   +1 more source

Peripheral immune responses to filoviruses in a reservoir versus spillover hosts reveal transcriptional correlates of disease

open access: yesFrontiers in Immunology
Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito   +13 more
doaj   +1 more source

Summary of filovirus sequelae and persistence in animal models.

open access: yes
Summary of filovirus sequelae and persistence in animal models.
Andrea Marzi (146489)   +1 more
core   +1 more source

Discovery of sclareol and sclareolide as filovirus entry inhibitors

open access: yes, 2019
Filoviruses cause severe hemorrhagic fever in humans. Ebola virus (EBOV) is the most contagious filovirus. Although compassionate treatments have been used during the latest Ebola outbreak, novel anti-EBOV agents are still urgently needed. In this study,
Ke Tang (39453)   +2 more
core   +1 more source

Doença Causada por Filovírus: Uma Atualização

open access: yesActa Médica Portuguesa
Os vírus Marburgo e Ébola pertencem à família Filoviridae e são conhecidos por causar doenças zoonóticas emergentes. Estes vírus apresentam alta letalidade e são facilmente transmissíveis de pessoa para pessoa, o que os torna potencialmente capazes de ...
Rafael Marx de Andrade   +3 more
doaj   +1 more source

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