Results 91 to 100 of about 6,894 (200)
Evolutionary maintenance of filovirus-like genes in bat genomes [PDF]
Background Little is known of the biological significance and evolutionary maintenance of integrated non-retroviral RNA virus genes in eukaryotic host genomes.
Derek J Taylor +7 more
core +1 more source
Evasion of the Interferon-Mediated Antiviral Response by Filoviruses
The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
doaj +1 more source
Magnified range maps of known and predicted filovirus-positive bat species.
Magnifications of hotspots of filovirus-positive bat species in sub-Saharan Africa (left), and hotspots in Southeast Asia showing overlapping geographic ranges for predicted new filovirus carriers within the 90th percentile probability (right).
Sarah E. Bowden (3153924) +5 more
core +1 more source
Intracellular events and cell fate in filovirus infection
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Olejnik J.
core
Ebola and Marburg viruses, biosafety level 4 pathogens, cause severe hemorrhaging and organ failure with high mortality. Although some FDA-approved vaccines or therapeutics like Ervebo for Zaire Ebola virus exist, still there is a lack of effective ...
W. Tamilarasi, B. J. Balamurugan
doaj +1 more source
Filovirus infections: science and innovation
Epidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva +2 more
doaj +1 more source
Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito +13 more
doaj +1 more source
Summary of filovirus sequelae and persistence in animal models.
Summary of filovirus sequelae and persistence in animal models.
Andrea Marzi (146489) +1 more
core +1 more source
Discovery of sclareol and sclareolide as filovirus entry inhibitors
Filoviruses cause severe hemorrhagic fever in humans. Ebola virus (EBOV) is the most contagious filovirus. Although compassionate treatments have been used during the latest Ebola outbreak, novel anti-EBOV agents are still urgently needed. In this study,
Ke Tang (39453) +2 more
core +1 more source
Doença Causada por Filovírus: Uma Atualização
Os vírus Marburgo e Ébola pertencem à família Filoviridae e são conhecidos por causar doenças zoonóticas emergentes. Estes vírus apresentam alta letalidade e são facilmente transmissíveis de pessoa para pessoa, o que os torna potencialmente capazes de ...
Rafael Marx de Andrade +3 more
doaj +1 more source

