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Rapid assessment of local disease control measures against the Marburg virus outbreak in Ethiopia in late 2025. [PDF]

open access: yesInfect Dis Model
Wu Q   +14 more
europepmc   +1 more source

Měnglà Virus VP40 Localizes to the Nucleus and Impedes the RIG-I Signaling Pathway. [PDF]

open access: yesViruses
Sweeney Gibbons J   +6 more
europepmc   +1 more source
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Filovirus budding

Virus Research, 2004
Family Filoviridae, which includes Ebola virus (EBOV) and Marburg virus (MARV), is a growing threat to human and non-human primate populations in central Africa. Although many facets of the filovirus life cycle remain to be deciphered, a great deal has been learned in recent years. In particular, a clearer understanding of the roles played by viral, as
Yoshihiro Kawaoka
exaly   +3 more sources

Mouse Models for Filovirus Infections [PDF]

open access: yesViruses, 2012
The filoviruses marburg- and ebolaviruses can cause severe hemorrhagic fever (HF) in humans and nonhuman primates. Because many cases have occurred in geographical areas lacking a medical research infrastructure, most studies of the pathogenesis of filoviral HF, and all efforts to develop drugs and vaccines, have been carried out in biocontainment ...
Steven Bradfute   +2 more
exaly   +4 more sources

Filovirus helical nucleocapsid structures

Microscopy, 2022
Abstract Filoviruses are filamentous enveloped viruses belonging to the family Filoviridae, in the order Mononegavirales. Some filovirus members, such as Ebola virus and Marburg virus, cause severe hemorrhagic fever in humans and non-human primates.
Shangfan Hu, Takeshi Noda
openaire   +2 more sources

Polymorphism of Filovirus Glycoproteins

2005
Publisher Summary Filoviral glycoproteins are encoded by gene 4 (GP gene) of the nonsegmented negative-strand RNA genome. Nonstructural glycoprotein (sGP) as well as Ebola virus (EBOV) and Marburgvirus (MBGV) GP undergo several posttranslational processing steps giving rise to a whole series of different glycoproteins.
Viktor E, Volchkov   +4 more
openaire   +2 more sources

Filovirus Filament Proteins

2018
Filoviruses are highly filamentous enveloped animal viruses that can cause severe haemorrhagic fevers. The filovirus ribonucleoprotein forms a highly organized double-layered helical nucleocapsid (NC) containing five different virally encoded proteins. The inner layer consists of NP, the RNA binding protein, complexed with the monopartite linear genome.
Daniel R, Beniac   +2 more
openaire   +2 more sources

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