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Viral disease outcomes are indistinguishable between experimentally infected bats and rodents
Farrell MJ +3 more
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(Uploaded by Plazi for the Bat Literature Project) Eight viruses are currently assigned to the family Filoviridae. Marburg virus, Sudan virus and, in particular, Ebola virus have received the most attention both by researchers and the public from 1967 to 2013.
Laura Böllinger +2 more
exaly +4 more sources
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2010
Abstract Filoviruses are large RNA viruses, of which Ebola virus and Marburg virus cause the most severe forms of viral haemorrhagic fever and have been best-studied because of fear of their misuse as bioterrorism agents. These are zoonotic viruses with reservoirs, most likely fruit-eating bats, in the rainforests of tropical Africa ...
Dieudonné Nkoghe +3 more
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Abstract Filoviruses are large RNA viruses, of which Ebola virus and Marburg virus cause the most severe forms of viral haemorrhagic fever and have been best-studied because of fear of their misuse as bioterrorism agents. These are zoonotic viruses with reservoirs, most likely fruit-eating bats, in the rainforests of tropical Africa ...
Dieudonné Nkoghe +3 more
+5 more sources
Reverse Genetics Systems for Filoviruses
Methods in Molecular Biology, 2023Filoviruses are causative agents of severe hemorrhagic fevers with high case fatality rates in humans. For studies of virus biology and the subsequent development of countermeasures, reverse genetic systems, and especially those facilitating the generation of recombinant filoviruses, are indispensable.
Bianca S Bodmer +2 more
exaly +3 more sources
Filoviruses: Interactions with the host cell [PDF]
The highly pathogenic filoviruses, Marburg and Ebola virus, are difficult to handle and knowledge of the interactions between filoviruses and their host cells remained enigmatic for many years. Two developments were crucial for the presented advances in our understanding of the cell biology of filoviruses, which is still fragmentary.
Larissa Kolesnikova, Stephan Becker
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2017
(Uploaded by Plazi for the Bat Literature Project) Filoviruses can cause severe and often fatal disease in humans. To date, there have been 47 outbreaks resulting in more than 31,500 cases of human illness and over 13,200 reported deaths. Since their discovery, researchers from many scientific disciplines have worked to better understand the natural ...
Brian R, Amman +3 more
openaire +2 more sources
(Uploaded by Plazi for the Bat Literature Project) Filoviruses can cause severe and often fatal disease in humans. To date, there have been 47 outbreaks resulting in more than 31,500 cases of human illness and over 13,200 reported deaths. Since their discovery, researchers from many scientific disciplines have worked to better understand the natural ...
Brian R, Amman +3 more
openaire +2 more sources
Reverse Genetics Systems for Filoviruses
Methods in Molecular Biology, 2017Filoviruses are among the most pathogenic viruses known to man. Reverse genetics systems, in particular full-length clone systems, allow the generation of recombinant filoviruses, which can be used to study virus biology, but also for applied uses such as screening for countermeasures.
Thomas Hoenen +2 more
exaly +3 more sources
Genomic transfers help to decipher the ancient evolution of filoviruses and interactions with vertebrate hosts [PDF]
Derek J Taylor
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Filoviruses as emerging pathogens
Seminars in Virology, 1994Abstract Of all the animal virus families that cause disease in man least is known about members of Filoviridae. This family, which contains Marburg and Ebola viruses, is one member of the order Mononegavirales, RNA viruses with a single negative genomic strand. The natural history of the filoviruses is unknown, but they have on occasion caused small
C J Peters +2 more
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