Results 21 to 30 of about 9,748 (234)

Detection of Filoviruses in Bats in Vietnam

Viruses, 2023
A new filovirus named Měnglà virus was found in bats in southern China in 2015. This species has been assigned to the new genus Dianlovirus and has only been detected in China.
M. Makenov, L. T. Le, O. Stukolova, Ekaterina V. Radyuk, E. Morozkin, Nga T. T. Bui, O. Zhurenkova, Manh N Dao, C. V. Nguyen, M. T. Luong, D. T. Nguyen, M. Fedorova, A. Valdokhina, V. Bulanenko, V. Akimkin, L. Karan   +15 more
semanticscholar   +1 more source

Emerging viruses: Cross-species transmission of coronaviruses, filoviruses, henipaviruses, and rotaviruses from bats

Cell Reports, 2022
Emerging infectious diseases, especially if caused by bat-borne viruses, significantly affect public health and the global economy. There is an urgent need to understand the mechanism of interspecies transmission, particularly to humans.
Jin Tian, Jiumeng Sun, Dongyan Li, Ningning Wang, Lifang Wang, Chang Zhang, Xiaorong Meng, Xiang Ji, M. Suchard, Xu Zhang, A. Lai, Shuo Su, M. Veit   +12 more
semanticscholar   +1 more source

Genomic transfers help to decipher the ancient evolution of filoviruses and interactions with vertebrate hosts

bioRxiv, 2023
Although several filoviruses are dangerous human pathogens, there is conflicting evidence regarding their origins and interactions with animal hosts. Here we attempt to improve this understanding using the paleoviral record over a geological time scale ...
Derek J. Taylor, Max H Barnhart
semanticscholar   +1 more source

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats [PDF]

, 2015
Biological factors that influence the host range and spillover of Ebola virus (EBOV) and other filoviruses remain enigmatic. While filoviruses infect diverse mammalian cell lines, we report that cells from African straw-colored fruit bats (Eidolon helvum)
Agnarsson, Allison, Almeida, Amman, Amman, Baker, Biesold, Bolger, Carette, Carroll, Carstea, Chandran, Cui, Côté, Daugherty, Deffieu, Delport, Demogines, Demogines, Drexler, Ebihara, Feldmann, Ge, Gire, Grabherr, He, Herbert, Hueffer, Jahrling, Jangra, Jayme, Jones, Kaelber, Kamins, Katzourakis, Krishnan, Kugelman, Kuhn, Kühl, Lee, Leroy, Li, Mali, Maruyama, Meyerson, Miller, Miller, Miller-Butterworth, Murrell, Negredo, Ng, Olival, Park, Parker, Paweska, Peel, Pond, Radoshitzky, Radoshitzky, Raj, Ren, Robertson, Ross, Runz, Ruxton, Sheahan, Swenson, Swenson, Takada, Taylor, Taylor, Taylor, Tong, Towner, Vanier, Volchkov, Wahl-Jensen, Wong, Yang   +78 more
core   +2 more sources

Emergent Risk Group-4 (RG-4) Filoviruses: A paradox in progress

Bioinformation, 2023
Filoviruses, categorized as World Health Organization (WHO) Risk Group 4 (RG-4) pathogens, represent significant global health risks due to their extraordinary virulence.
John T. Sinnott, Kami Kim, C. Somboonwit, Conor Cosnett, David Segal, P. Shapshak   +5 more
semanticscholar   +1 more source

Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism

Cell Reports, 2020
Summary: Fruit bats are suspected to be natural hosts of filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV). Interestingly, however, previous studies suggest that these viruses have different tropisms depending on the bat species.
Yoshihiro Takadate, Tatsunari Kondoh, Manabu Igarashi, Junki Maruyama, Rashid Manzoor, Hirohito Ogawa, Masahiro Kajihara, Wakako Furuyama, Masahiro Sato, Hiroko Miyamoto, Reiko Yoshida, Terence E. Hill, Alexander N. Freiberg, Heinz Feldmann, Andrea Marzi, Ayato Takada   +15 more
doaj   +1 more source

Development and Structural Analysis of Antibody Therapeutics for Filoviruses

Pathogens, 2022
The filoviruses, including ebolaviruses and marburgviruses, are among the world’s deadliest pathogens. As the only surface-exposed protein on mature virions, their glycoprotein GP is the focus of current therapeutic monoclonal antibody discovery efforts.
Xiaoying Yu, E. Saphire
semanticscholar   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet, Barnard, Dale, Carrion, Ricardo, Lu, Kai, McKerrow, James H, Nunneley, Jerritt W, Pöhlmann, Stefan, Renslo, Adam R, Simmons, Graham, Vedantham, Punitha, Zhou, Yanchen   +10 more
core   +1 more source

Novel Filoviruses, Hantavirus, and Rhabdovirus in Freshwater Fish, Switzerland, 2017

Emerging Infectious Diseases, 2021
European perch (Perca fluviatilis) are increasingly farmed as a human food source. Viral infections of European perch remain largely unexplored, thereby putting farm populations at incalculable risk for devastating fish epizootics and presenting a ...
Melanie M Hierweger, M. Koch, M. Rupp, P. Maes, Nicholas Di Paola, R. Bruggmann, J. Kuhn, H. Schmidt-Posthaus, T. Seuberlich   +8 more
semanticscholar   +1 more source

Filiviruses of southeast Asia, China and Europe (review)

Журнал инфектологии, 2019
Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov, Yu. V. Kononova, T. M. Luong   +2 more
doaj   +1 more source