Results 31 to 40 of about 9,748 (234)

A high-throughput, polymerase-targeted RT-PCR for broad detection of mammalian filoviruses. [PDF]

Microbiol Spectr
Filoviruses are some of the most lethal viruses in the modern world, and increasing numbers of filovirus species and genera have been discovered in recent years.
Cui N, Perez YL, Hume AJ, Nunley BE, Kong K, Mills MG, Xie H, Greninger AL.   +7 more
europepmc   +2 more sources

Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]

, 2016
Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii, Edmunds, Kelly, Hooper, Lee, Hunter, Paul, Pond, Katherine   +4 more
core   +3 more sources

The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]

, 2016
Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S, Farzan, Michael, Gorman, Matthew J, Hyde, Jennifer L, Poddar, Subhajit   +4 more
core   +2 more sources

Sphingosine Kinases Promote Ebola Virus Infection and Can Be Targeted to Inhibit Filoviruses, Coronaviruses, and Arenaviruses Using Late Endocytic Trafficking to Enter Cells

bioRxiv, 2022
Entry of enveloped viruses in host cells requires the fusion of the viral and host cell membranes, a process that is facilitated by viral fusion proteins protruding from the viral envelope.
Corina M Stewart, Yuxia Bo, K. Fu, M. Chan, R. Kozak, K. Y. Apperley, G. Laroche, Redaet Daniel, André M. Beauchemin, G. Kobinger, D. Kobasa, M. Côté   +11 more
semanticscholar   +1 more source

LLOVIU VIRUS - A NOVEL FILOVIRUS, ENDEMIC IN EUROPE

Вопросы вирусологии, 2018
The data on a recently revealed novel filovirus (Lloviu virus, family Filoviridae, genera Cuevavirus) in Europe are viewed in this issue. The molecular-biological properties of genome fragments of Lloviu virus were isolated from perished bats ...
T. E. Sizikova, V. N. Lebedev, N. V. Karulina, S. V. Borisevich   +3 more
doaj   +1 more source

Intracellular Events and Cell Fate in Filovirus Infection

Viruses, 2011
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Elena Ryabchikova, Ronald B. Corley, Elke Mühlberger, Judith Olejnik   +3 more
doaj   +1 more source

AAV Vectored Immunoprophylaxis for Filovirus Infections

Tropical Medicine and Infectious Disease, 2020
Filoviruses are among the deadliest infectious agents known to man, causing severe hemorrhagic fever, with up to 90% fatality rates. The 2014 Ebola outbreak in West Africa resulted in over 28,000 infections, demonstrating the large-scale human health and
Amira D. Rghei, Laura P. van Lieshout, Lisa A. Santry, Matthew M. Guilleman, Sylvia P. Thomas, Leonardo Susta, Khalil Karimi, Byram W. Bridle, Sarah K. Wootton   +8 more
doaj   +1 more source

Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV) [PDF]

, 2017
The International Committee on Taxonomy of Viruses (ICTV) is charged with the task of developing, refining, and maintaining a universal virus taxonomy.
Dempsey, Donald M., Hendrickson, Robert Curtis, Lefkowitz, Elliot J., Orton, Richard J., Siddell, Stuart G., Smith, Donald B.   +5 more
core   +3 more sources

Comparative analyses of small molecule and antibody inhibition on glycoprotein‐mediated entry of Měnglà virus with other filoviruses

Journal of Medical Virology, 2022
The ability of viruses in the Filoviridae family (Ebola virus [EBOV] and Marburg virus [MARV]) to cause severe human disease and their pandemic potential makes all emerging filoviral pathogens a concern to humanity.
L. Cooper, J. G. Achi, Lijun Rong
semanticscholar   +1 more source

Development of a Měnglà virus minigenome and comparison of its polymerase complexes with those of other filoviruses. [PDF]

Virol Sin
Ebola virus (EBOV) and Marburg virus (MARV), members of the Filoviridae family, are highly pathogenic and can cause hemorrhagic fevers, significantly impacting human society.
Xie SZ, Yao K, Li B, Peng C, Yang XL, Shi ZL.   +5 more
europepmc   +2 more sources