Results 31 to 40 of about 7,695 (151)

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Filoviruses: Interactions with the host cell [PDF]

Cellular and Molecular Life Sciences, 2007
The highly pathogenic filoviruses, Marburg and Ebola virus, are difficult to handle and knowledge of the interactions between filoviruses and their host cells remained enigmatic for many years. Two developments were crucial for the presented advances in our understanding of the cell biology of filoviruses, which is still fragmentary.
Olga Dolnik, Larissa Kolesnikova, Stephan Becker   +2 more
openaire   +3 more sources

Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses. [PDF]

, 2014
Budding of filoviruses, arenaviruses, and rhabdoviruses is facilitated by subversion of host proteins, such as Nedd4 E3 ubiquitin ligase, by viral PPxY late (L) budding domains expressed within the matrix proteins of these RNA viruses.
Davis, Benjamin, Freedman, Bruce D, Han, Ziying, Harty, Ronald N, Lee, Michael S, Liu, Yuliang, Lu, Jianhong, Olson, Mark A, Reitz, Allen B, Ruthel, Gordon, Schnell, Matthias J, Wrobel, Jay E   +11 more
core   +2 more sources

Potential mammalian filovirus reservoirs [PDF]

, 2010
Centers for Disease Control and Prevention http://www.cdc.gov/ncidod/EID/vol10no12/04-0346.htmEbola and Marburg viruses are maintained in unknown reservoir species; spillover into human populations results in occasional human cases or epidemics.
Carroll, Darin S., Johnson, Karl M., Mills, James N., Peterson, A. Townsend   +3 more
core   +4 more sources

Recommendations for dealing with waste contaminated with Ebola virus: a Hazard Analysis of Critical Control Points approach [PDF]

, 2016
Objective To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks.
Ahmed A Mohamedani, Benedict M Mutua, Brainard, Chepurnov, Diana J Bell, Edward Muchiri, Guy Howard, Harvey Minnigh, Iain Lake, Joseph Matofari, Julii Brainard, Julius M Ndambuki, Katherine Pond, Kelly L Edmunds, Lutendo S Mudau, Maggie Montgomery, Mark D Sobsey, Mark Zeitoun, Mike van der Es, Paul R Hunter, Peter Maes, Roger Few, Samir Dervisevic, Samira Abd Elrahman, Sarah Morter, Tsimbiri P Fedha   +25 more
core   +2 more sources

Recent Advances in Sustainable Total Synthesis and Chiral Pool Strategies with Emphasis on (−)‐Sclareol in Natural Products Synthesis

European Journal of Organic Chemistry, Volume 28, Issue 8, February 24, 2025.
There are continuous efforts to improve total syntheses of natural products, particularly their sustainability, such as developing effective chiral pool approaches relying on a wide spectrum of natural chirons, including (−)‐sclareol as one of the most useful natural chirons.
Ayyoub Selka, Abdelnasser Abidli, Lucie Schiavo, Loïc Jeanmart, Gilles Hanquet, William D. Lubell   +5 more
wiley   +1 more source

Undiscovered Bat Hosts of Filoviruses

PLOS Neglected Tropical Diseases, 2016
Ebola and other filoviruses pose significant public health and conservation threats by causing high mortality in primates, including humans. Preventing future outbreaks of ebolavirus depends on identifying wildlife reservoirs, but extraordinarily high biodiversity of potential hosts in temporally dynamic environments of equatorial Africa contributes to
Barbara A. Han, John Paul Schmidt, Laura W. Alexander, Sarah E. Bowden, David T. S. Hayman, John M. Drake   +5 more
openaire   +6 more sources

Ebolavirus evolution and emergence are associated with land use change

Ecological Monographs, Volume 95, Issue 1, February 2025.
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange, Thomas R. Barnum, David J. McIver, Matthew LeBreton, Karen Saylors, Charles Kumakamba, Sara Lowes, Eduardo Montero, Robert L. Cohen   +8 more
wiley   +1 more source

“Filoviruses”: a real pandemic threat?

EMBO Molecular Medicine, 2009
Filoviruses are zoonotic and among the deadliest viruses known to mankind, with mortality rates in outbreaks reaching up to 90%. Despite numerous efforts to identify the host reservoir(s), the transmission cycle of filoviruses between the animal host(s) and humans remains unclear.
Byron E. E. Martina, Albert D. M. E. Osterhaus   +1 more
openaire   +3 more sources

Modern building structures are a landscape‐level driver of bat–human exposure risk in Kenya

Frontiers in Ecology and the Environment, Volume 23, Issue 1, February 2025.
Identifying the locations and drivers of high‐risk interfaces between humans and wildlife is crucial for managing zoonotic disease risk. We suggest that continent‐wide improvements to residential housing in Africa are inadvertently creating artificial roosting habitat for synanthropic free‐tailed bats (family Molossidae), and that improved buildings ...
Tamika J Lunn, Reilly T Jackson, Paul W Webala, Joseph G Ogola, Kristian M Forbes   +4 more
wiley   +1 more source