Results 41 to 50 of about 21,222 (177)

Rutin Stabilises β‐Catenin Through GSK3β Inhibition to Promote Hair Follicle Regeneration

Cell Proliferation, EarlyView.
Rutin directly binds to GSK3β, stabilising β‐catenin and activating Wnt/β‐catenin signalling to drive hair cycle.
Yanyan Zhang, Yuanjie Zhu, Mengyu Jin, Jing Chen, Siqi Yuan, Minjia Yuan, Yuou Sha, Qingmei Liu, Wenyu Wu, Juan Wang, Xiaolei Ding   +10 more
wiley   +1 more source

Validirane RP-RP-HPLC i TLC metode za simultano određivanje tamsulozin hidroklorida i finasterida u istom dozirnom pripravku [PDF]

, 2010
Reversed phase high-performance liquid chromatography (RP-HPLC) and thin-layer chromatography (TLC) methods have been developed and validated for simultaneous estimation of tamsulosin hydrochloride and finasteride in bulk drug and in combined dosage ...
A. Sangita, A. Syed, C. Xiaohong, Dipti Patel, F. Guo, J. Hardman, K. Basavaiah, L. Din, M. Constanzer, N. Ramakrishna, Natubhai Patel, P. Keski-Rahkonen, P. Ptacek, Y. Soeishi   +13 more
core   +2 more sources

Efficacy of finasteride for treating patients with androgenetic alopecia who are pileous in other areas: A pilot study in Japan

Indian Journal of Dermatology, 2014
Background: Androgenetic alopecia (AGA) involves androgen-dependent hair loss and finasteride is an established treatment for the disease. However, reports of the influence of finasteride on hair growth in other areas of the body are lacking.
Toru Inadomi
doaj   +1 more source

Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer

EBioMedicine, 2016
Background: In the Prostate Cancer Prevention Trial, finasteride selectively suppressed low-grade prostate cancer and significantly reduced the incidence of prostate cancer in men treated with finasteride compared with placebo.
Jeri Kim, John W. Davis, Eric A. Klein, Cristina Magi-Galluzzi, Yair Lotan, John F. Ward, Louis L. Pisters, Joseph W. Basler, Curtis A. Pettaway, Andrew Stephenson, Elsa M. Li Ning Tapia, Eleni Efstathiou, Xuemei Wang, Kim-Anh Do, J. Jack Lee, Ivan P. Gorlov, Lana A. Vornik, Ashraful M. Hoque, Ina N. Prokhorova, Howard L. Parnes, Scott M. Lippman, Ian M. Thompson, Powel H. Brown, Christopher J. Logothetis, Patricia Troncoso   +24 more
doaj   +1 more source

Prescribing Patterns in Pediatric Hidradenitis Suppurativa

Pediatric Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin condition increasingly diagnosed in pediatric populations; however, data on treatment practices in this group remains limited. In this retrospective study of 163 patients diagnosed with HS ≤ 18 years of age, we found that treatment patterns varied significantly by disease severity.
Hannah Neimy, Courtney L. Walker, Lara Wine Lee, Colleen H. Cotton   +3 more
wiley   +1 more source

A new pharmacological target for Tourette Syndrome? [PDF]

, 2016
Tourette Syndrome (TS) is a childhood-onset neurological disorder characterised by multiple motor tics and one or more phonic tics. Number, frequency and tic complexity vary over time.
Frau, Roberto
core   +1 more source

Comparison between dutasteride and finasteride in hair regrowth and reversal of miniaturization in male and female androgenetic alopecia: a systematic review

Dermatology Reports
Nowadays androgenetic alopecia (AGA) has become a common concern of affected subjects of both sexes. Finasteride is approved by the Food and Drug Administration for the treatment of male AGA.
Almuntaserbellah Almudaimeegh, Hanadi AlMutairi, Fatimah AlTassan, Yomna AlQuraishi, Khalid Nabil Nagshabandi   +4 more
doaj   +1 more source

The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial.

PLoS ONE, 2018
BackgroundFinasteride, a 5-alpha reductase inhibitor may have effects on biomarkers such as prostate-specific antigen (PSA) that could be leveraged to improve screening.ObjectiveTo determine the predictive characteristics of biomarkers for prostate ...
Javier Hernandez, Jonathan Gelfond, Martin Goros, Michael A Liss, Yuanyuan Liang, Donna Ankerst, Ian M Thompson, Robin J Leach   +7 more
doaj   +1 more source

Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase III trial

BJU International, Volume 137, Issue 4, Page 698-707, April 2026.
Objectives To evaluate the efficacy and safety of a fixed‐dose combination (FDC) of dutasteride and tadalafil vs monotherapy in patients with benign prostatic hyperplasia (BPH). Patients and Methods This phase III trial enrolled 667 patients. After screening and washout, eligible patients were stratified by the baseline International Prostate Symptom ...
Seung Wook Lee, Seung Hwan Lee, Jae Heon Kim, Joon Hwa Noh, Jun Ho Lee, U‐Syn Ha, Cheol Young Oh, Taek Won Kang, Gyeongseop Lee, Sangchul Lee, Deok Hyun Han, Jun Hyun Han, Sang Hoon Song, Hyun Jun Park, Byung Ha Chung, Gyeong Eun Min, In Gab Jeong, Kyung Hyun Moon, Won Tae Kim, Ji Youl Lee, Choung‐Soo Kim   +20 more
wiley   +1 more source

Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors:population based cohort study [PDF]

, 2019
OBJECTIVE: To investigate the incidence of new onset type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors (dutasteride or finasteride) for long term treatment of benign prostatic hyperplasia.
Andrew, Ruth, Kao-Yang, Yea-Huei, Lai, Edward Chia-Cheng, MacDonald, Thomas M., Walker, Brian R., Wei, Li   +5 more
core   +4 more sources