Results 31 to 40 of about 20,810 (248)
The transcriptome of the Bermuda fireworm Odontosyllis enopla (Annelida: Syllidae): A unique luciferase gene family and putative epitoky-related genes. [PDF]
PLoS ONE, 2018 The Bermuda fireworm Odontosyllis enopla exhibits an extremely tight circalunar circadian behavior that results in an impressive bioluminescent mating swarm, thought to be due to a conventional luciferase-mediated oxidation of a light-emitting luciferin.
Mercer R Brugler +3 more
doaj +1 more source
Molecular Imaging, 2007 Bioluminescence imaging (BLI) of luciferase reporters in small animal models offers an attractive approach to monitor regulation of gene expression, signal transduction, and protein-protein interactions, as well as following tumor progression, cell ...
Shimon Gross +4 more
doaj +1 more source
CBT‐Cys click reaction for optical bioimaging in vivo
View, 2023 Derived from the D‐luciferin regeneration pathway in firefly body, the click condensation reaction between 2‐cyanobenzothiazole (CBT) and D‐cysteine (Cys) (CBT‐Cys click reaction) possesses unique advantages, including superior biocompatibility, high ...
Xinyi Hu +5 more
doaj +1 more source
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
Advanced Functional Materials, EarlyView.FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum. [PDF]
PLoS Neglected Tropical Diseases, 2018 There is need for a more efficient cell-based assay amenable to high-throughput drug screening against Giardia lamblia. Here, we report the development of a screening method utilizing G.
Kelly M Hennessey +10 more
doaj +1 more source
Firefly luciferase can use L-luciferin to produce light [PDF]
Biochemical Journal, 1996 l-Luciferin is a competitive inhibitor of firefly luciferase with a Ki between 3 and 4 μM. Furthermore l-luciferin can serve as an alternative substrate for light production. Catalysis of l-luciferin can be observed in the absence of, or at low concentrations of, d-luciferin.
openaire +2 more sources
ホタル生物発光における発光制御機構の化学生物学的研究 [PDF]
, 2016 Firefly bioluminescence is an enzymatic reaction, which requires Mg2+, ATP, and O2. The mechanism of this bioluminescence is as follows; first, the luciferase catalyzes the adenylylation of the luciferin and then the oxygenation of the adenylylated ...
Satoshi Iwano, 岩野 智
core +2 more sources
Advanced Functional Materials, EarlyView.Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin +4 more
wiley +1 more source
Time Course of Bioluminescent Signal in Orthotopic and Heterotopic Brain Tumors in Nude Mice
BioTechniques, 2003 In vivo bioluminescence imaging is becoming increasingly popular. Quantification of bioluminescent signals requires knowledge of the variability and reproducibility of this technique.
J.S. Burgos +6 more
doaj +1 more source
Protein sterilization method of firefly luciferase using reduced pressure and molecular sieves [PDF]
, 1973 The sterilization of the protein fruitfly luciferase under conditions that prevent denaturation is examined. Denaturation is prevented by heating the protein in contact with molecular seives and under a reduced pressure of the order of 0.00005 ...
Chappelle, E. W., Rich, E., Jr.
core +1 more source