Results 51 to 60 of about 20,810 (248)
Bioluminescence emission of the firefly [PDF]
, 2007 We have recorded _in vivo_ emission and time-resolved spectra of the firefly species _Pyrophorus noctilucus_. The emission spectrum shows the FWHM value for this particular species to be 55 nm, which is significantly smaller than the half widths reported
Anurup Gohain Barua +3 more
core +1 more source
Programmable probiotics for detection of cancer in urine [PDF]
, 2014 Rapid advances in the forward engineering of genetic circuitry in living cells has positioned synthetic biology as a potential means to solve numerous biomedical problems, including disease diagnosis and therapy.
Allen, Kaitlin N. +7 more
core +1 more source
Advanced Science, EarlyView.This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu +17 more
wiley +1 more source
Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin
eLife, 2019 Bioluminescence imaging (BLI) is ubiquitous in scientific research for the sensitive tracking of biological processes in small animal models. However, due to the attenuation of visible light by tissue, and the limited set of near-infrared bioluminescent ...
Cassandra L Stowe +14 more
doaj +1 more source
Stereoisomeric bio‐inversion key to biosynthesis of firefly
FEBS Letters, 2006 The chirality of the luciferin substrate is critical to the luciferin–luciferase reaction producing bioluminescence. In firefly, the biosynthetic pathway of d‐luciferin is still unclear, although it can be synthesized in vitro from d‐cysteine. Here, we show that the firefly produces both d‐ and l‐luciferin, and that the amount of active d‐luciferin ...
Niwa, Kazuki +2 more
openaire +2 more sources
Light detection instrument Patent [PDF]
, 1970 Detection instrument for light emitted from ATP biochemical ...
Chappelle, E. W., Hoffman, D. G.
core +1 more source
Synthesis and Luminescence Properties of Near-Infrared N-Heterocyclic Luciferin Analogues for In Vivo Optical Imaging [PDF]
, 2019 As a means of achieving highly sensitive bioluminescence imaging of deep tissues utilizing the firefly luciferin-luciferase (L-L) reaction, we previously reported a luciferin analogue, AkaLumine, which exhibits high cell-permeability and emits near ...
Masahiro Kiyama +9 more
core +2 more sources
NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation
Advanced Science, EarlyView.NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi +14 more
wiley +1 more source
Reversible low-light induced photoswitching of crowned spiropyran-DO3A complexed with gadolinium(III) ions. [PDF]
, 2012 Photoswitchable spiropyran has been conjugated to the crowned ring system DO3A, which improves its solubility in dipolar and polar media and stabilizes the merocyanine isomer. Adding the lanthanide ion gadolinium(III) to the macrocyclic ring system leads
Brueggemann, Chantal +6 more
core +4 more sources
PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy
Advanced Science, EarlyView.The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao +24 more
wiley +1 more source