Results 181 to 190 of about 2,532,132 (302)

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Effect of fish oil as an adjunct therapy to metformin on vascular and cardiac health in women with polyendocrine metabolic ovarian syndrome: protocol for a randomised, placebo-controlled clinical trial. [PDF]

BMJ Open
Sydora B, Ghosh M, Chambers S, Haase A, Davenport M, Beaulieu C, Thompson R, Windram J, Becher H, Raggi P, Vine D.   +10 more
europepmc   +1 more source

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

Effects of UMP, Choline, and Fish Oil on Synaptic Integrity and Motor Coordination in an Alzheimer's Disease Mouse Model. [PDF]

Int J Mol Sci
Keskinoz EN, Footohi G, Celik M, Acar D, Ozgun G, Elmas MA, Yavuz İ, Ada E, Sari E, Ay B, Unal MC, Ulus İH, Arbak S, Suyen G, Oz-Arslan D.   +14 more
europepmc   +1 more source

Fish Oil [PDF]

, 2020
openaire   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Fish oil-derived fatty acids during pregnancy and risk of neurodevelopmental disorders in children at age 10 - A randomized controlled trial. [PDF]

Transl Psychiatry
Rosenberg JB, Sevelsted A, Jepsen JRM, Vinding R, Mohammadzadeh P, Hernández Lorca M, Horner D, Sørensen ME, Fagerlund B, Bilenberg N, Pantelis C, Glenthøj BY, Chawes B, Stokholm J, Ebdrup BH, Bønnelykke K.   +15 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Omega-3-rich fish oil lipid emulsions prevent sepsis-driven mesenteric hypoperfusion and multiorgan injury in a murine model. [PDF]

Turk J Med Sci
Öz G, Özçelebi E, Göçmen AY, Sökmensüer C, Yildirim S, Topeli A, Iskit AB.   +6 more
europepmc   +1 more source

Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors

Advanced Science, EarlyView.
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu, Yi Lu, Xuetong Shi, Zhangmin Wan, Peijin Jiang, Minke Yang, Qingshi Tu, Orlando J. Rojas   +7 more
wiley   +1 more source