Results 31 to 40 of about 2,140,934 (313)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Welfare and health of fish fed vegetable oils as alternative lipid sources to fish oil

open access: yes, 2010
Over the last few years, fish health and welfare in aquaculture production have received increasing attention. A well-balanced dietary fatty acid profile is a determinant of animal health and welfare, and thus there is the potential that the replacement ...
Montero, Daniel, Izquierdo, Marisol
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Addition of Fish Oil to Cream Cheese Affects Lipid Oxidation, Sensory Stability and Microstructure

open access: yesAgriculture, 2012
The objective of this study was to investigate the differences in the oxidative stability during storage of fish oil enriched cream cheeses when fish oil was added either as neat oil or pre-emulsified oil with sodium caseinate, whey protein isolate, or a
Andy Horsewell   +7 more
doaj   +1 more source

Index to Anvil Points Oil Shale Research Center files

open access: yes, 2022
Technical memorandum no. 67-41.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated during 1965, 1966 ...

core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the second meeting

open access: yes, 2022
Includes charts.Unscanned charts, contact the Library for more information. These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical ...

core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Evaluation of oil-water separation techniques on retort no. 3

open access: yes, 2022
Technical memorandum no. 67-21.Includes charts.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...

core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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