Results 11 to 20 of about 126,813 (257)
Dissecting the Fitness Costs of Complex Mutations [PDF]
Molecular Biology and Evolution, 2021 Abstract The fitness cost of complex pleiotropic mutations is generally difficult to assess. On the one hand, it is necessary to identify which molecular properties are directly altered by the mutation. On the other, this alteration modifies the activity of many genetic targets with uncertain consequences.
Pablo Yubero, Juan F Poyatos
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Fitness Costs of Female Reproduction [PDF]
Evolution, 1997 Here we present a method to estimate the fitness costs of trade-offs between reproduction and survival. The approach demonstrates that there is an apparent fitness cost to mating, but not to egg production, in the fruit fly Drosophila melanogaster. In light of this result, we argue that fitness tradeoffs in females that result from resources females ...
Marc, Tatar, Daniel E L, Promislow
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Fitness costs of resistance to insecticides in insects
Frontiers in Physiology, 2023 The chemical application is considered one of the most crucial methods for controlling insect pests, especially in intensive farming practices. Owing to the chemical application, insect pests are exposed to toxic chemical insecticides along with other stress factors in the environment. Insects require energy and resources for survival and adaptation to
Gul, Hina +6 more
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Frontiers in Microbiology, 2022 Daptomycin is a last-line antibiotic used in the treatment of multidrug-resistant Enterococcus faecium infections. Alarmingly, daptomycin-resistant E. faecium isolates have emerged.
Weiliang Zeng +10 more
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Compensating the Fitness Costs of Synonymous Mutations [PDF]
Molecular Biology and Evolution, 2016 Synonymous mutations do not change the sequence of the polypeptide but they may still influence fitness. We investigated in Salmonella enterica how four synonymous mutations in the rpsT gene (encoding ribosomal protein S20) reduce fitness (i.e., growth rate) and the mechanisms by which this cost can be genetically compensated.
Knöppel, Anna +2 more
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Pathogens, 2021 HIV cure studies require patients to enter an analytical treatment interruption (ATI). Here, we describe previously unanalyzed data that sheds light on ATI dynamics in PLHIV (People Living with HIV).
James R. Hunter +7 more
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Frontiers in Microbiology, 2020 Plasmids can provide advantageous traits to host bacteria, although they may impose a fitness cost. Chromosome-encoded factors are important for regulating the expression of genes on plasmids, and host chromosomes may differ in terms of their ...
Hibiki Kawano +8 more
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Biology, 2022 The fall armyworm, Spodoptera frugiperda (J.E. Smith), is a voracious insect pest that is difficult to control due to resistance to insecticides and Bt proteins.
Muhammad Hafeez +14 more
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Frontiers in Plant Science, 2023 IntroductionUnderstanding fitness costs associated with fungicide resistance is critical to improve resistance management strategies. E198A in b-tubulin confers resistance to the fungicide thiophanate-methyl and has been widely reported in several plant ...
Scott D. Cosseboom +2 more
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The Cost of Laboratory Fittings [PDF]
Nature, 1920 IN all directions we have at the present time evidence of a growing enthusiasm for education in the field of natural science. Students are being turned away from our schools and universities for lack of accommodation, and the new Education Act has given great encouragement to science teaching.
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